22 Results for "

cAMP analogue

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "cAMP analogue" in MCE Product Catalog:

17
17 Publications Verification
Cat. No.: HY-P0036
CAS No.: 83150-76-9
Synonyms: SMS 201-995
Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly .
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3
3 Cited Publications
Cat. No.: HY-108742A
Purity:  99.86%
Synonyms: BA 058 TFA; BIM 44058 TFA
Target:  

Arrestin PTHR

Research Areas:  

Metabolic Disease Endocrinology Cancer

Abaloparatide TFA (BA 058 TFA) is a parathyroid hormone receptor 1 (PTHR1) analogue. Abaloparatide TFA also is a selective PTHR1 activator. Abaloparatide TFA enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide TFA enhances bone formation and cortical structure in mice. Abaloparatide TFA has the potential for the research of osteoporosis .
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Cat. No.: HY-107544
CAS No.: 1152197-23-3
Target:  

PKA

Research Areas:  

Metabolic Disease

8-pCPT-2'-O-Me-cAMP-AM is a cyclic AMP analogue, selectively activates Epac-Rap signaling pathway. 8-pCPT-2'-O-Me-cAMP-AM protects renal function by activating Epac from ischemia injury. 8-pCPT-2'-O-Me-cAMP-AM also stimulates insulin secretion by interaction with PKA pathway .
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Cat. No.: HY-P0036A
CAS No.: 1607842-55-6
Synonyms: SMS 201-995 dihydrochloride
Octreotide (SMS 201-995) hydrochloride is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide hydrochloride can bind to the somatostatin receptors which are mainly subtypes 2, 3 and 5. Octreotide hydrochloride increases Gi activity and reduces intracellular cAMP production. Octreotide hydrochloride has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly .
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Cat. No.: HY-P0036B
CAS No.: 135467-16-2
Synonyms: SMS 201-995 pamoate
Octreotide (SMS 201-995) pamoate is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide pamoate can bind to the somatostatin receptors which are mainly subtypes 2, 3 and 5. Octreotide pamoate increases Gi activity and reduces intracellular cAMP production. Octreotide pamoate has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly .
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Cat. No.: HY-P0036S4
Synonyms: SMS 201-995-d8 acetate
Octreotide-d8 (acetate) (SMS 201-995-d8 (acetate)) is deuterium labeled Octreotide. Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly .
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Cat. No.: HY-P11246
CAS No.: 3057097-31-8
Target:  

RXFP Receptor

Research Areas:  

Metabolic Disease

A13:B7-24-GG is an engineered analogue of insulin-like peptide 5 (INSL5), a selective RXFP4 agonist with a Ki value of 2.29 nM. A13:B7-24-GG has an extremely low binding affinity for RXFP3 (Ki = 602.56 nM) and an inhibitory effect on cAMP (EC50) of 1.17 nM. Activation of RXFP4 by A13:B7-24-GG leads to the recruitment of β-Arrestin2, with an EC50 of 22.39 nM. A13:B7-24-GG can be used for research on chronic constipation .
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Cat. No.: HY-123396
CAS No.: 41941-56-4
Purity:  ≥99.0%
Target:  

PKA

Research Areas:  

Cancer

8-Chloro-cAMP is a cAMP analogue that induces growth arrest, and modulates cAMP-dependent PKA activity. 8-Chloro-cAMP has anticancer activity .
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Cat. No.: HY-123396A
CAS No.: 124705-03-9
Target:  

PKA

Research Areas:  

Cancer

8-Chloro-cAMP sodium is a cAMP analogue that induces growth arrest, and modulates cAMP-dependent PKA activity. 8-Chloro-cAMP sodium has anticancer activity .
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Cat. No.: HY-131766
CAS No.: 40269-29-2
Synonyms: 2'-O-Methyladenosine-3',5'-cyclic monophosphate
Target:  

Ras

Research Areas:  

Others

2'-O-Me-cAMP is an analogue of natural signal molecule cAMP and a selective stimulator of the exchange factors activated by cAMP (Epac) with low membrane permeability .
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Cat. No.: HY-134340
CAS No.: 612513-16-3
Synonyms: 8-(4-Methoxyphenylthio)-2'-O-Me-cAMP
Target:  

Ras

Research Areas:  

Others

8-pMeOPT-2'-O-Me-cAMP is an analogue of the signal molecule cAMP and a potent stimulator of exchange factors activated by cAMP (Epac), while it doesn't activate PKA as cAMP does .
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Cat. No.: HY-134302
CAS No.: 59212-44-1
Synonyms: 8-Hexylamino-cAMP
Target:  

PKA

Research Areas:  

Others

8-HA-cAMP is a membrane-permeable cAMP analogue and an activator of cAMP-dependent protein kinase and PKA I. 8-HA-cAMP exerts metabolic stability towards mammalian cyclic nucleotide-responsive phosphodiesterases .
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Cat. No.: HY-134298
CAS No.: 72549-36-1
Synonyms: 8-(4-Chlorophenylthio)-N6-phenyl-cAMP
Target:  

PKA

Research Areas:  

Others

8-CPT-6-Phe-cAMP is an analogue of signal molecule cAMP and a potent protein kinase A (PKA) activator .
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Cat. No.: HY-131772
CAS No.: 214276-80-9
Target:  

Fluorescent Dye

Research Areas:  

Others

2-AHA-cAMP is an analogue of natural signal molecule cAMP and an activator of cAMP-dependent protein kinase. 2-AHA-cAMP has a free terminal primary amino group, which can be used for coupling to gels or fluorescent dyes .
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Cat. No.: HY-134264
CAS No.: 612513-13-0
Target:  

Ras

8-Br-2'-O-Me-cAMP is an analogue of the signal molecule cyclic AMP (cAMP). 8-Br-2'-O-Me-cAMP is an agonist of exchange factors activated by cAMP (Epac), while it doesn't activate PKA as cAMP do. 8-Br-2'-O-Me-cAMP can be used in cardiovascular disease research .
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Cat. No.: HY-134308
CAS No.: 221905-51-7
Target:  

Fluorescent Dye

Research Areas:  

Others

8-NBD-cAMP sodium is a fluorescently labeled cyclic adenosine phosphate (cAMP) analogue. 8-NBD-cAMP sodium retains a similar biological activity to cAMP, regulating their activity by binding to specific proteins such as EPACs or PKA. 8-NBD-cAMP sodium can be used in fluorescent competitive binding experiments to evaluate the binding affinity of newly synthesized EPAC1 agonists to EPAC1 proteins .
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Cat. No.: HY-134332
CAS No.: 78710-84-6
Synonyms: 8-(4-Chlorophenylthio)-5'-AMP
Target:  

PKA PKG

Research Areas:  

Others

8-pCPT-5'-AMP is an analogue of 5'-AMP and a lipophilic activator of PKA, PKG and Epac (exchange protein activated by cAMP) .
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Cat. No.: HY-106893
CAS No.: 139403-31-9
Synonyms: SM 10902
Pimilprost (SM 10902) is a prostaglandin I1 analogue. Pimilprost exhibits antithrombotic and increases cAMP levels. Pimilprost can promote wound healing through the stimulation of angiogenesis and the improvement of blood flow in diabetic mice. Pimilprost can be used for the research of metabolic and cardiovascular disease, such as diabetes .
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Cat. No.: HY-131844
CAS No.: 40871-55-4
Synonyms: N6-Benzoyladenosine-5'-O-monophosphate
Target:  

Endogenous Metabolite

Research Areas:  

Others

6-Bnz-5'-AMP is a lipophilic analogue of adenosine-5'-O-monophosphate and a potential metabolite of N 6-Benzoyl-cAMP. 6-Bnz-5'-AMP exhibits some cytokinin activity in tobacco and soybean tissue culture assays .
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Cat. No.: HY-P0036S2
CAS No.: 1240797-41-4
Synonyms: SMS 201-995-d8
Octreotide-d8 (SMS 201-995-d8) is deuterium labeled Octreotide. Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly .
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