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caner

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By Targets:	AMPK (1) Apoptosis (1) Autophagy (1) CXCR (1) Cytochrome P450 (1) Deubiquitinase (1) DNA/RNA Synthesis (3) Endogenous Metabolite (2) Environmental Pollutants (1) Ferroptosis (1) Fungal (1) Glutathione Peroxidase (1) Herbicide (3) Integrin (1) Isotope-Labeled Compounds (2) Parasite (1) Reactive Oxygen Species (ROS) (1) Reference Standards (1)
By Research Areas:	Cancer (6) Cardiovascular Disease (1) Endocrinology (1) Infection (2) Metabolic Disease (3) Neurological Disease (1)

Inhibitors & Agonists

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-19855

AZD-5069 Maximum Cited Publications 11 Publications Verification	CXCR	Endocrinology Cancer
AZD-5069 is a potent CXCR2 chemokine receptor antagonist, used for caner treatment.

HY-P990117

Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10)	Integrin	Cardiovascular Disease Cancer
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) is a mouse-derived Osteopontin/SPP1 IgG1 κ type antibody inhibitor. Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) blocks Angiotensin II (HY-13948)-induced DNA synthesis and collagen gel contraction in cardiac fibroblasts. Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) significantly inhibits tumor growth in CT26 or MC38 tumors mice models .

HY-121267

Dicamba	Environmental Pollutants DNA/RNA Synthesis Herbicide	Others
Dicamba is a herbicide. Dicamba is currently used in agriculture and gardening to control the growth of different unwanted vegetable species, mainly in cereal grain crops, but also on sugar cane and soybeans, among others. Dicambais induces significant DNA damage. Dicambais induces genotoxicity and cytotoxicity.

HY-N6998

Paederosidic acid 1 Publications Verification	Apoptosis	Cancer
Paederosidic acid is isolated from P.?scandens with anticancer and anti‐inflammation activities. Paederosidic acid inhibits lung caner cells via inducing mitochondria-mediated apoptosis .

HY-N7266

Obtusifoliol 1 Publications Verification	Cytochrome P450 Parasite	Infection Cancer
Obtusifoliol is a specific CYP51 inhibitor, Obtusifoliol shows the affinity with K_d values of 1.2 μM and 1.4 μM for Trypanosoma brucei (TB) and human CYP51, respectively .

HY-N8425

Octacosanoic acid Montanic acid	Endogenous Metabolite	Metabolic Disease
Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models .

HY-176557

NCI677397	Deubiquitinase Ferroptosis Reactive Oxygen Species (ROS) Glutathione Peroxidase Autophagy	Cancer
NCI677397 is a USP24 inhibitor. NCI677397 increases lipid ROS, activates cholesterol and fatty acid biosynthesis, degrades ABC transporters, GPX4 and DHFR through the autophagy pathway, decreases the level of P-gp and ultimately leads to ferroptosis in drug-resistant cancer cells. NCI677397 can be used for the study of lung caner and brain cancer .

HY-N7394

Galbacin (3S)-Zuonin A	AMPK	Metabolic Disease Cancer
Galbacin ((3S)-Zuonin A), the epimer of (-)-Zuonin A (HY-N7394A), is a AMPK activator. Galbacin can be isolated from Myristica fragrans (nutmeg). Galbacin stimulates AMPK enzyme in differentiated C2C12 cells. Galbacin also has anticancer activity, and inhibits the proliferation of lymphocyte and tumor cells. Galbacin prevents weight gain in diet-induced mice model. Galbacin can be used for metabolic syndrome (including obesity and type-2 diabetes) and caners research .

HY-117496

Ampelopsin A	Fungal	Infection Neurological Disease
Ampelopsin A is a antifungal agent and can be isolated from the Vitis vinifera canes. Ampelopsin A shows neuroprotective effects .

HY-N8425R

Octacosanoic acid (Standard) Montanic acid (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Octacosanoic acid (Standard) is the analytical standard of Octacosanoic acid. This product is intended for research and analytical applications. Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models .

HY-121267S1

Dicamba-d3	Isotope-Labeled Compounds Herbicide DNA/RNA Synthesis	Others
Dicamba-d₃ is the deuterium labeled Dicamba (HY-121267 ) . Dicamba is a herbicide. Dicamba is currently used in agriculture and gardening to control the growth of different unwanted vegetable species, mainly in cereal grain crops, but also on sugar cane and soybeans, among others. Dicambais induces significant DNA damage. Dicambais induces genotoxicity and cytotoxicity .

HY-121267S

Dicamba-13C6	Isotope-Labeled Compounds Herbicide DNA/RNA Synthesis	Others
Dicamba- ¹³C₆ is the ¹³C labeled Dicamba (HY-121267). Dicamba is a herbicide. Dicamba is currently used in agriculture and gardening to control the growth of different unwanted vegetable species, mainly in cereal grain crops, but also on sugar cane and soybeans, among others. Dicambais induces significant DNA damage. Dicambais induces genotoxicity and cytotoxicity .

Cat. No.	Product Name	Target	Research Area	Image

HY-P990117

Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10)	Integrin	Cardiovascular Disease Cancer
Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) is a mouse-derived Osteopontin/SPP1 IgG1 κ type antibody inhibitor. Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) blocks Angiotensin II (HY-13948)-induced DNA synthesis and collagen gel contraction in cardiac fibroblasts. Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) significantly inhibits tumor growth in CT26 or MC38 tumors mice models .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6998

Paederosidic acid 1 Publications Verification	other families Iridoids Classification of Application Fields Terpenoids Paederia scandens (Lour.) Merr. Rubiaceae Plants Disease Research Fields Source Classification Cancer	Apoptosis
Paederosidic acid is isolated from P.?scandens with anticancer and anti‐inflammation activities. Paederosidic acid inhibits lung caner cells via inducing mitochondria-mediated apoptosis .

HY-N7266

Obtusifoliol 1 Publications Verification	Infection Natural Products Human Gut Microbiota Metabolites Sorghum bicolor (Linn.) Moench Microorganisms Classification of Application Fields Gramineae Plants Endogenous metabolite Disease Research Fields Source Classification	Cytochrome P450 Parasite
Obtusifoliol is a specific CYP51 inhibitor, Obtusifoliol shows the affinity with K_d values of 1.2 μM and 1.4 μM for Trypanosoma brucei (TB) and human CYP51, respectively .

HY-N8425

Octacosanoic acid Montanic acid	Croton caudatus Geisel. Croton. Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Euphorbiaceae Plants Disease Research Fields Source Classification	Endogenous Metabolite
Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models .

HY-N7394

Galbacin (3S)-Zuonin A	Natural Products Virola surinamensis (Rol. ex Rottb.) Warb. Myristicaceae Plants Source Classification	AMPK
Galbacin ((3S)-Zuonin A), the epimer of (-)-Zuonin A (HY-N7394A), is a AMPK activator. Galbacin can be isolated from Myristica fragrans (nutmeg). Galbacin stimulates AMPK enzyme in differentiated C2C12 cells. Galbacin also has anticancer activity, and inhibits the proliferation of lymphocyte and tumor cells. Galbacin prevents weight gain in diet-induced mice model. Galbacin can be used for metabolic syndrome (including obesity and type-2 diabetes) and caners research .

HY-117496

Ampelopsin A	Polygonaceae Phenols Polyphenols Fallopia multiflora (Thunb.) Harald. Plants Source Classification	Fungal
Ampelopsin A is a antifungal agent and can be isolated from the Vitis vinifera canes. Ampelopsin A shows neuroprotective effects .

HY-N8425R

Octacosanoic acid (Standard) Montanic acid (Standard)	Croton caudatus Geisel. Croton. Ketones, Aldehydes, Acids Euphorbiaceae Plants Source Classification	Reference Standards Endogenous Metabolite
Octacosanoic acid (Standard) is the analytical standard of Octacosanoic acid. This product is intended for research and analytical applications. Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models .

Cat. No.	Product Name	Chemical Structure

HY-121267S1

Dicamba-d3
Dicamba-d₃ is the deuterium labeled Dicamba (HY-121267 ) . Dicamba is a herbicide. Dicamba is currently used in agriculture and gardening to control the growth of different unwanted vegetable species, mainly in cereal grain crops, but also on sugar cane and soybeans, among others. Dicambais induces significant DNA damage. Dicambais induces genotoxicity and cytotoxicity .

HY-121267S

Dicamba-13C6
Dicamba- ¹³C₆ is the ¹³C labeled Dicamba (HY-121267). Dicamba is a herbicide. Dicamba is currently used in agriculture and gardening to control the growth of different unwanted vegetable species, mainly in cereal grain crops, but also on sugar cane and soybeans, among others. Dicambais induces significant DNA damage. Dicambais induces genotoxicity and cytotoxicity .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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