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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
diosgenin
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "diosgenin" in MCE Product Catalog:
11
5
5 Cited Publications
Cat. No.: HY-N2389
CAS No.: 50773-42-7
Category:
Paris polyphylla Smith var. chinensis (Franch.) Hara Plants Liliaceae Extract Disease Research Fields Saccharides Cancer
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Cat. No.: HY-N0730
CAS No.: 14144-06-0
Category:
Human Gut Microbiota Metabolites Plants Other Families Extract Endogenous metabolite Steroids
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Cat. No.: HY-N0730R
CAS No.: 14144-06-0
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Cat. No.: HY-N12002
CAS No.: 1072072-37-7
Category:
Plants Melanthiaceae Extract Paris polyphylla var. yunnanensis (Franch.) Hand.-Mzt. Steroids
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Cat. No.: HY-151286
CAS No.: 2812356-72-0
Antitumor agent-73 is a Diosgenin (HY-N0177) derivative, which inhibits STAT3 signaling and activates Pdia3/ERp57 exogenously. Antitumor agent-73 shows potent anti-tumor activity against various cancer cell lines, 7.9-341.7-fold stronger than Diosgenin .
Cat. No.: HY-N2389R
CAS No.: 50773-42-7
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Cat. No.: HY-147538
CAS No.: 2396562-55-1
Antitumor agent-64 (Compound 8d) is a diosgenin derivative. Antitumor agent-64 exhibits potent cytotoxic activity against A549 cell line. Antitumor agent-64 induces A549 cells apoptosis via the mitochondria-related pathway .
Cat. No.: HY-W145687
CAS No.: 32471-99-1
Synonyms: diosgenin-3-O-Β-D-glucuronide
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Category:
Cat. No.: HY-N20657
CAS No.: 1644058-82-1
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Cat. No.: HY-184737
Target:
Drug Derivative Bcl-2 Family Caspase PARP Mitochondrial Metabolism ATP Synthase Reactive Oxygen Species (ROS) Apoptosis
Research Areas:
TPP-C8-CO-DSG bromide is a derivative of Diosgenin (HY-N0177) and an anticancer agent. TPP-C8-CO-DSG bromide downregulates Bcl-2 expression and upregulates Bax expression. TPP-C8-CO-DSG bromide promotes the cleavage of Caspase 9, Caspase 3 and PARP-1. TPP-C8-CO-DSG bromide depolarizes mitochondrial membrane potential, reduces intracellular ATP production, and induces intracellular ROS accumulation. TPP-C8-CO-DSG bromide promotes Apoptosis. TPP-C8-CO-DSG bromide exhibits anticancer activity against prostate cancer, breast cancer, lung adenocarcinoma, cervical cancer and colorectal cancer. TPP-C8-CO-DSG bromide can be used in the research of cervical cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
