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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
emesis
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "emesis" in MCE Product Catalog:
Synonyms: SCH619734
Target:
Research Areas:
Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model .
Cat. No.: HY-16436
CAS No.: 914462-92-3
Synonyms: SCH619734 hydrochloride hydrate
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Rolapitant hydrochloride hydrate (SCH619734 hydrochloride hydrate) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant hydrochloride hydrate does not interact with CYP3A4. Rolapitant hydrochloride hydrate shows potent anti-emetic activity in a ferret emesis model .
Cat. No.: HY-B1017
CAS No.: 15622-65-8
Synonyms: EN-1733A
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Molindone hydrochloride (EN-1733A) is an orally active and brain-penetrant dopamine D2/D5 receptor antagonist. Molindone hydrochloride shows antipsychotic and antidepressant-like activities. Molindone hydrochloride suppresses spontaneous locomotion, and antagonizes apomorphine-induced emesis. Molindone hydrochloride can be used for the research of neurological disease .
Cat. No.: HY-178269
CAS No.: 2238886-63-8
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SCH-720881 is the active metabolite of Rolapitant (HY-14751). Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model .
Cat. No.: HY-N6799
CAS No.: 36519-25-2
Cat. No.: HY-105201
CAS No.: 129300-27-2
Synonyms: FK1052 free base
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Fabesetron (FK1052) is an orally active 5-HT3 receptor antagonist with 5-HT4 receptor antagonistic activity. Fabesetron (FK1052) can be used in the study for both acute and delayed emesis induced by cancer chemotherapy .
Cat. No.: HY-N1523
CAS No.: 93675-85-5
Category:
Natural Products Neurological Disease Plants Forsythia suspensa (Thunb.) Vahl Oleaceae Extract Disease Research Fields
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Cat. No.: HY-69317
CAS No.: 159925-31-2
Synonyms: PMNPQ
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RS14203 is an orally active type IV cyclic nucleotide phosphodiesterase (PDE IV) inhibitor which can induce emesis .
Cat. No.: HY-129423
CAS No.: 552292-58-7
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Telmapitant is an orally active NK1R antagonist. Telmapitant has antiemetic effect and can be used for the research of delayed onset emesis .
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Haloperidide (R3201) is a neuroleptic compound. Haloperidide is a potent and selective anti-emetic agent. Haloperidide antagonizes Apomorphine (HY-12723)-induced emesis in dogs .
Cat. No.: HY-19456
CAS No.: 1239279-30-1
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SSR-241586 is an antagonist of neurokinin receptors. SSR-241586 is shown to be active in the treatment of depression, schizophrenia, urinary trouble, emesis, and irritable bowel syndrome (IBS) .
Cat. No.: HY-B1573A
CAS No.: 36504-94-6
Synonyms: AY-23,028; dl-Butaclamol hydrochloride
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(±)-Butaclamol hydrochloride (AY-23,028) is the antagonist for adrenergic receptor and dopamine receptor. (±)-Butaclamol hydrochloride antagonizes amphetamine or Apomorphine (HY-12723)-induced stereotyped behaviors and emesis, inhibits discriminative avoidance behavior, and induces catalepsy in rats models .
Cat. No.: HY-105201A
CAS No.: 129299-90-7
Synonyms: FK1052
Target:
Research Areas:
Fabesetron (FK1052) hydrochloride is an orally active 5-HT3 receptor antagonist with 5-HT4 receptor antagonistic activity. Fabesetron hydrochloride can be used in the study for both acute and delayed emesis induced by cancer chemotherapy .
Cat. No.: HY-14751A
CAS No.: 858102-79-1
Synonyms: SCH619734 hydrochloride
Target:
Research Areas:
Rolapitant (SCH619734) hydrochloride is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant hydrochloride does not interact with CYP3A4. Rolapitant hydrochloride shows potent anti-emetic activity in a ferret emesis model .
Cat. No.: HY-116578R
CAS No.: 14008-44-7
Synonyms: EXP999 (Standard); RP9965 (Standard)
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Metopimazine (Standard) is the analytical standard of Metopimazine. This product is intended for research and analytical applications. Metopimazine (EXP999) is a phenothiazine derivative used to prevent emesis during chemotherapy. Metopimazine belongs to the anti-dopaminergic anti-emetics (ADA) class. Metopimazine can be used for the research of gastroenteritis (GE) .
Cat. No.: HY-115895
CAS No.: 23915-73-3
Synonyms: CI-686 free base
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Trebenzomine (CI-686 free base) is a centrally acting psychotropic compound. Trebenzomine has both neuroleptic and stimulant activity. Trebenzomine potentiates Methamphetamine-induced self-stimulation. Trebenzomine reduces septal
hyperirritability, suppression of conditioned avoidance behavior, blocks Apomorphine (HY-12723)-induced emesis in dogs .
Cat. No.: HY-117952
CAS No.: 187724-86-3
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L 743310 is a non-peptide, selective antagonist of the human neurokinin hNK1 receptor, with high affinity for primate and cloned human hNK1 receptors and lower affinity for rodent NK1 receptors. L 743310 inhibits resiniferatoxin-induced plasma protein extravasation in guinea pig esophagus. L 743310 has a dose-dependent inhibitory effect on cisplatin-induced emesis .
Cat. No.: HY-14751R
CAS No.: 552292-08-7
Synonyms: SCH619734 (Standard)
Research Areas:
Rolapitant (Standard) is the analytical standard of Rolapitant. This product is intended for research and analytical applications. Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model .
Cat. No.: HY-106982
CAS No.: 147116-64-1
Synonyms: CJ-11,974
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Ezlopitant (CJ-11,974) is a selective, non-peptidic neurokinin-1 (NK-1)-receptor antagonist. Ezlopitant inhibits both acute and delayed emetic reactions induced by Cisplatin (HY-17394) in ferrets via acting on NK1 receptors in the central nervous system. Ezlopitant has the potential for pain, chemotherapy-induced emesis and irritable bowel syndrome research .
Cat. No.: HY-B1017R
CAS No.: 15622-65-8
Synonyms: EN-1733A (Standard)
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Research Areas:
Molindone hydrochloride (Standard) is the analytical standard of Molindone hydrochloride (HY-B1017). This product is intended for research and analytical applications. Molindone hydrochloride (EN-1733A) is an orally active and brain-penetrant dopamine D2/D5 receptor antagonist. Molindone hydrochloride shows antipsychotic and antidepressant-like activities. Molindone hydrochloride suppresses spontaneous locomotion, and antagonizes apomorphine-induced emesis. Molindone hydrochloride can be used for the research of neurological disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
