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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
enzyme-substrate complexes
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "enzyme-substrate complexes" in MCE Product Catalog:
Synonyms: Hegzadesil; Trimethylamine hydrochloric acid; Trimethylamine monohydrochloride
Category:
Cardiovascular Disease Digitalis purpurea Linn. Scrophulariaceae Plants Disease Research Fields Steroids
Target:
Cat. No.: HY-Y0504S3
CAS No.: 18856-86-5
Cat. No.: HY-W015616
CAS No.: 2550-26-7
Synonyms: 4-Penylbutan-2-one
Category:
Thymelaeaceae Ketones, Aldehydes, Acids Metabolic Disease Plants Disease Research Fields Aquilaria sinensis (Lour.) Spreng.
Target:
Synonyms: Hegzadesil (Standard); Trimethylamine hydrochloric acid (Standard); Trimethylamine monohydrochloride (Standard)
Category:
Cat. No.: HY-Y0504S
CAS No.: 2483824-12-8
Cat. No.: HY-Y0504S1
CAS No.: 107766-37-0
Synonyms: Hegzadesil-d10; Trimethylamine hydrochloric acid-d10; Trimethylamine monohydrochloride-d10
Cat. No.: HY-126877
CAS No.: 78582-17-9
3-Deaza-2 '-deoxyadenosine is a nucleoside analog synthesized from 2' -deoxyadenosine. 3-Deaza-2 '-deoxyadenosine inhibits RNA synthesis by binding to ribose fragments of ribonucleotides, thereby preventing the formation of enzyme-substrate complexes, thereby preventing chain elongation, It can also inhibit DNA synthesis by binding deoxyribose fragments of DNA and preventing DNA polymerase from adding nucleotides to the growth chain. 3-Deaza-2 '-deoxyadenosine has antiviral activity .
Cat. No.: HY-Y0504S4
CAS No.: 347840-14-6
Synonyms: Hegzadesil-d6; Trimethylamine hydrochloric acid-d6; Trimethylamine monohydrochloride-d6
Cat. No.: HY-W585905
CAS No.: 286013-00-1
Cat. No.: HY-Y0504S2
CAS No.: 108451-51-0
Synonyms: Hegzadesil-15N; Trimethylamine hydrochloric acid-15N; Trimethylamine monohydrochloride-15N
Cat. No.: HY-181744
Target:
Research Areas:
AChE-IN-108 is a potent mixed-type acetylcholinesterase (AChE) inhibitor with an in vitro IC50 of 0.17 nM. AChE-IN-108 acts on both free AChE and the enzyme-substrate complex to exert mixed-type inhibition. AChE-IN-108 can be used for the study of acetylcholinesterase inhibition in Alzheimer’s disease (AD) .
Cat. No.: HY-136933R
CAS No.: 4562-36-1
Target:
Cat. No.: HY-184382
Target:
Research Areas:
α-Amylase-IN-15 is a dual inhibitor of α-amylase and α-glucosidase, with IC50 values of 6.7 μM and 18.55 μM, respectively, and a Ki value of 50.9 μM against α-amylase. α-Amylase-IN-15 binds to both free α-amylase and the enzyme-substrate complex. By inhibiting α-glucosidase, α-Amylase-IN-15 achieves dual inhibition of carbohydrate metabolic enzymes. α-Amylase-IN-15 can be used in the research of type 2 diabetes .
Cat. No.: HY-W714186
CAS No.: 60207-93-4
Synonyms: Etaconazole
Etaconazol (Etaconazole) is an azole fungicide. Etaconazol possesses endocrine-disrupting potential and inhibits placental steroidogenesis by suppressing 3β-hydroxysteroid dehydrogenase (3β-HSD1). Etaconazol binds to the NAD +/steroid-binding site of the target enzyme and acts on both the free enzyme and enzyme-substrate complex to inhibit their activity .
Cat. No.: HY-181161
Target:
Research Areas:
AChE-IN-107 is a selective acetylcholinesterase (AChE) inhibitor with an IC50 of 0.22 μM and a Ki of 0.207 μM. AChE-IN-107 shows no inhibitory effect on equine serum BChE at 10 μM. AChE-IN-107 exhibits mixed-type inhibition of electric eel acetylcholinesterase, binding to both free enzyme and enzyme-substrate complex. AChE-IN-107 acts as a cytotoxin, reduces cell viability in hepatocellular carcinoma HepG2 cells.AChE-IN-107 can be used for the research of alzheimer's disease .
Cat. No.: HY-W015616R
CAS No.: 2550-26-7
Synonyms: 4-Penylbutan-2-one (Standard)
Target:
Cat. No.: HY-182776
Target:
Research Areas:
α-Glucosidase-IN-115 (compound 3m) is a non-competitive α-Glucosidase inhibitor with an IC50 value of 45.07 μM. α-Glucosidase-IN-115 is applicable to the research of type 2 diabetes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
