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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
extrapyramidal
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "extrapyramidal" in MCE Product Catalog:
1
Research Areas:
Blonanserin (AD-5423) is a potent and orally active 5-HT2A (Ki=0.812 nM) and dopamine D2 receptor (Ki =0.142 nM) antagonist. Blonanserin is usually acts as an atypical antipsychotic agent and can be used for the research of extrapyramidal symptoms, excessive sedation, or hypotension .
Target:
Research Areas:
Pericyazine (Propericiazine) is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis . Pericyazine is a selective D2-dopamine receptor antagonist . Pericyazine has adrenolytic, anticholinergic, and extrapyramidal effects .
Target:
Research Areas:
Tropatepine is an orally active anticholinergic agent and can be used in the research of neurological diseases such as Parkinson's disease and extrapyramidal syndromes .
Cat. No.: HY-106584
CAS No.: 89419-40-9
Synonyms: Clospipramine
Research Areas:
Mosapramine (Clospipramine) is an orally active antipsychotic agent and one of the metabolites of Clocapramine (HY-B2073) after oral absorption. Mosapramine exerts its effects by specifically binding to striatal dopamine D2 receptors and frontal lobe 5-HT2 receptors, with a D2/5-HT2 receptor occupancy ratio of 7.4. Mosapramine induces typical neuropharmacological responses in rat brain regions, including extrapyramidal symptoms, hyperprolactinemia, increased salivation, constipation, and upregulated Fos protein expression. Mosapramine also features a reduced incidence of weight loss. Mosapramine is applicable to research related to schizophrenia .
Cat. No.: HY-106605
CAS No.: 61325-80-2
Synonyms: LY 120363
Target:
Research Areas:
Flumezapine (LY 120363) is a potent and balanced antagonist of the dopamine D2 receptor and the 5-hydroxytryptamine receptor (5-HT receptor). Flumezapine does not alter the increase in serum cortisol caused by κ-opioid receptor agonists. Flumezapine inhibits the conditioned avoidance response in rats and has a low risk of extrapyramidal side effects. Flumezapine can be used in antipsychotic research .
Cat. No.: HY-115192
CAS No.: 100935-99-7
Synonyms: ent-MK-458 hydrochloride; ent-L-647339 hydrochloride
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Research Areas:
ent-Naxagolide (ent-MK-458) hydrochloride is a dopamine D2-receptor agonist. ent-Naxagolide hydrochloride can be used in the study of extrapyramidal diseases and Parkinson's syndrome.
Cat. No.: HY-106820
CAS No.: 86580-77-0
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Research Areas:
BRL 34778 is a potent, selective and orally active dopamine D2 receptor antagonist with a Ki of 2.14 nM. BRL 34778 exhibits antipsychotic activity with low activity for extrapyramidal effects and sedation. BRL 34778 can be used for the research of neurological disease, such as schizophrenia .
Cat. No.: HY-13575A
CAS No.: 132812-45-4
Synonyms: AD-5423 dihydrochloride
Research Areas:
Blonanserin dihydrochloride is a potent and orally active 5-HT2A and dopamine D2 receptor antagonist, with Ki values of 0.812 and 0.142 nM, respectively. Blonanserin dihydrochloride is usually acts as an atypical antipsychotic agent, and can be used for the research of extrapyramidal symptoms, excessive sedation, or hypotension .
Cat. No.: HY-119385
CAS No.: 79262-47-8
Target:
Research Areas:
Savoxepin mesylate is a D2 dopamine receptor (D2 Dopamine Receptor) antagonist with antipsychotic activity. Savoxepin mesylate selectively blocks dopamine D2 receptors in the hippocampus while having no significant effect on D2 receptors in the striatum. This selective blockade helps reduce the risk of extrapyramidal side effects (EPS) .
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Pericyazine (Standard) is the analytical standard of Pericyazine. This product is intended for research and analytical applications. Pericyazine (Propericiazine) is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis . Pericyazine is a selective D2-dopamine receptor antagonist . Pericyazine has adrenolytic, anticholinergic, and extrapyramidal effects .
Cat. No.: HY-13575R
CAS No.: 132810-10-7
Synonyms: AD-5423 (Standard)
Research Areas:
Blonanserin (Standard) is the analytical standard of Blonanserin. This product is intended for research and analytical applications. Blonanserin (AD-5423) is a potent and orally active 5-HT2A (Ki=0.812 nM) and dopamine D2 receptor (Ki =0.142 nM) antagonist. Blonanserin is usually acts as an atypical antipsychotic agent and can be used for the research of extrapyramidal symptoms, excessive sedation, or hypotension .
Cat. No.: HY-106605S
Synonyms: LY 120363-d8 hydrochloride
Cat. No.: HY-W740116
CAS No.: 10488-36-5
Synonyms: TOF hydrochloride
Target:
Research Areas:
Tofenacin hydrochloride (TOF hydrochloride) is an orally active weak anticholinergic compound. Tofenacin hydrochloride can be used to study extrapyramidal symptoms and depressive side effects associated with the use of Fluphenazine decanoate (HY-B1904) .
Cat. No.: HY-W740116A
CAS No.: 15301-93-6
Synonyms: TOF
Target:
Research Areas:
Tofenacin (TOF) is an orally active weak anticholinergic compound. Tofenacin can be used to study extrapyramidal symptoms and depressive side effects associated with the use of Fluphenazine decanoate (HY-B1904) .
Cat. No.: HY-105710R
CAS No.: 27574-24-9
Research Areas:
Tropatepine (Standard) is the analytical standard of Tropatepine (HY-105710). This product is intended for research and analytical applications. Tropatepine is an orally active anticholinergic agent and can be used in the research of neurological diseases such as Parkinson's disease and extrapyramidal syndromes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
