29 Results for "

factor IX

" in MedChemExpress (MCE) Product Catalog:
Products (29)

29 Results for "factor IX" in MCE Product Catalog:

20
20 Publications Verification
Cat. No.: HY-145405
CAS No.: 1220890-25-4
Pureté:  99.91%
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .
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1
1 Cited Publications
Cat. No.: HY-B0924
CAS No.: 117-37-3
Target:  

Thrombin

Domaines de recherche:  

Cardiovascular Disease

Anisindione is an oral indandione anticoagulant. Anisindione inhibits the formation of active procoagulant factors II, VII, IX and X. Anisindione can be used in anticoagulation-related research .
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1 Cited Publications
Cat. No.: HY-P70231
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuCoagulation factor IX/F9, His; F9; Coagulation factor IX; Christmas factor; Plasma thromboplastin component; Coagulation factor IXa light chain; Coagulation factor IXa heavy chain
Species:  
Source:  
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Cat. No.: HY-P9940
CAS No.: 1610943-06-0
Synonyms: ACE-910; RG6013

Target:  

Factor VIII

Domaines de recherche:  

Cardiovascular Disease

Emicizumab is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab can be used for hemophilia A research .
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Cat. No.: HY-E70541B
CAS No.: 9001-28-9
Domaines de recherche:  

Cardiovascular Disease

Canine Factor IX is a functional coagulation factor. Canine Factor IX shortens whole blood clotting time and activated partial thromboplastin time, and restores coagulation function. After intramuscular administration via rAAV vector in hemophilia B dogs, Canine Factor IX maintains a sustained circulating level for at least 1 year, partially corrects the hemophilia B phenotype in a dose-dependent manner, and its plasma expression persists for more than 17 months. Canine Factor IX is applicable to relevant research on hemophilia B .
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Cat. No.: HY-122142A
CAS No.: 127428-47-1
Synonyms: S-2366 (hydrochloride)
Domaines de recherche:  

Others

Pyr-​Pro-​Arg-​pNA (S-2366) hydrochloride is a chromogenic peptidyl substrate, and a noncompetitive inhibitor that occupies the active sites of FXIa and FXIa-LC to block factor IX activation. Pyr-​Pro-​Arg-​pNA hydrochloride functions as a hydrolyzable substrate for FXIa’s catalytic domain, human APC, murine APC, and purified plasma kallikrein .
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Cat. No.: HY-14854
CAS No.: 867257-26-9
Pureté:  98.65%
Synonyms: ATI-5923
Target:  

VKOR

Domaines de recherche:  

Cardiovascular Disease

Tecarfarin (ATI-5923) is an orally active and non-competitive vitamin K epoxide reductase (VKOR) antagonist, and impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X . Tecarfarin has the antithrombotic activity .
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Cat. No.: HY-107966A
CAS No.: 37270-89-6
Synonyms: Nadroparin calcium (MW 3600-5000)
Heparin (Nadroparin) calcium (MW 3600-5000) is an anticoagulant which binds reversibly to antithrombin III (ATIII) to form a heparin-antithrombin III complex. The complex binds to and irreversibly inactivates thrombin and other activated clotting factors IX, X, XI, and XII and prevents the transformation of fibrinogen to fibrin .
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Cat. No.: HY-P4243A
Target:  

Ser/Thr Protease

Domaines de recherche:  

Others

Dansyl-Glu-Gly-Arg-Chloromethylketone TFA is a protease inhibitor, and inhibits serine/threonine proteases. Dansyl-Glu-Gly-Arg-Chloromethylketone TFA inhibits activated porcine factor IX .
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Cat. No.: HY-P4243
CAS No.: 69024-84-6
Target:  

Ser/Thr Protease

Domaines de recherche:  

Others

Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor, and inhibits serine/threonine proteases. Dansyl-Glu-Gly-Arg-Chloromethylketone inhibits activated porcine factor IX .
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Cat. No.: HY-112935
CAS No.: 181054-95-5
Synonyms: BAX326; Coagulation factor IX [Recombinant]; BeneFIX

Target:  

Ser/Thr Protease

Domaines de recherche:  

Others

Nonacog alfa (BAX326) is a recombinant human factor IX that can be used for the research of haemophilia B .
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Cat. No.: HY-122142
CAS No.: 72194-57-1
Synonyms: S-2366
Domaines de recherche:  

Inflammation/Immunology

Pyr-​Pro-​Arg-​pNA (S-2366) is a chromogenic peptidyl substrate, and a noncompetitive inhibitor that occupies the active sites of FXIa and FXIa-LC to block factor IX activation. Pyr-​Pro-​Arg-​pNA functions as a hydrolyzable substrate for FXIa’s catalytic domain, human APC, murine APC, and purified plasma kallikrein .
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Cat. No.: HY-174232
Domaines de recherche:  

Cancer

EGFR/CA-IX-IN-1 (Compound 14) is a dual inhibitor against epidermal growth factor receptor (EGFR) and carbonic anhydrase IX (CA-IX) with IC50 values of 5.92 nM and 63 nM, respectively. EGFR/CA-IX-IN-1 shows strong cytotoxicity against breast cancer cells (MDA-MB-231, MCF-7) with IC50 values of 5.78 μM and 8.05 μM, respectively. EGFR/CA-IX-IN-1 inhibits the catalytic activity of CA-IX, up-regulates BAX/Bcl-2, activates caspases, and arrests the cell cycle at the G1 phase. EGFR/CA-IX-IN-1 is promising for research of breast cancer .
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Cat. No.: HY-E70541A
CAS No.: 9001-28-9
Domaines de recherche:  

Cardiovascular Disease

Bovine Factor IX is prepared from freshly collected bovine plasma. Factor IX activated by the Factor VIIa/tissue factor/phospholipid complex is responsible for the activation of Factor X to Factor Xa .
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Cat. No.: HY-107966
CAS No.: 37270-89-6
Synonyms: Nadroparin calcium (MW 15000-19000)
Heparin calcium (MW 15000-19000) is an anticoagulant which binds reversibly to antithrombin III (ATIII) to form a heparin-antithrombin III complex. The complex binds to and irreversibly inactivates thrombin and other activated clotting factors IX, X, XI, and XII and prevents the transformation of fibrinogen to fibrin .
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Cat. No.: HY-121244
CAS No.: 117-52-2
Target:  

Factor Xa

Coumafuryl is a kind of coumarin rodenticide. Coumafuryl inhibits the metabolic cycle of vitamin K that causes the interference with protein biosynthesis of vitamin K-dependent coagulant factors (II, VII, IX, and X factors) in the liver .
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Cat. No.: HY-E70393J
Target:  

Factor XI

Domaines de recherche:  

Others

Bovine Factor XIa is an enzyme, which is involved in the intrinsic pathway of blood coagulation. Bovine Factor XIa is highly selective and exhibits a minimal extended substrate recognition site of at least five residues long. Bovine Factor XIa is reactive as Bovine Factor IXa (HY-E70393I) does, that it cleaves all the peptides bearing factor IX activation site sequences .
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Cat. No.: HY-P991213
Synonyms: RIXubis

Target:  

Factor XI

Domaines de recherche:  

Cardiovascular Disease

Nonacog gamma is a coagulation factor IX (FIX) supplement. Nonacog gamma activates coagulation factor X (FX), promotes the generation of thrombin, and then converts fibrinogen into fibrin, forming a stable blood clot to exert hemostatic activity. Nonacog gamma is promising for research of hemophilia B .
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Cat. No.: HY-B0924R
CAS No.: 117-37-3
Domaines de recherche:  

Cardiovascular Disease

Anisindione (Standard) is the analytical standard of Anisindione. This product is intended for research and analytical applications. Anisindione is an oral indandione anticoagulant. Anisindione inhibits the formation of active procoagulant factors II, VII, IX and X. Anisindione can be used in anticoagulation-related research.
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Cat. No.: HY-P9940A

Target:  

Factor VIII

Domaines de recherche:  

Cardiovascular Disease

Emicizumab (Anti-F9 & Factor IX) is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab (Anti-F9 & Factor IX) can be used for hemophilia A research .
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