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Results for "

fluorescent product

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Fluorescent Dye (89) Akt (1) Amyloid-β (4) Apoptosis (2) Bacterial (5) Bcl-2 Family (1) Biochemical Assay Reagents (11) Btk (1) Caspase (1) Cathepsin (3) Cholinesterase (ChE) (1) ClpP (1) Complement System (1) COX (1) Cytochrome P450 (1) DNA Stain (1) DNA/RNA Synthesis (1) Drug Derivative (4) Drug Intermediate (4) Drug Metabolite (1) Endogenous Metabolite (3) Fungal (3) Glycosidase (1) HDAC (1) HIF/HIF Prolyl-Hydroxylase (1) HIV (2) HSV (1) Influenza Virus (1) Interleukin Related (1) Isotope-Labeled Compounds (1) JNK (1) Monoamine Oxidase (1) Monoamine Transporter (1) Monocarboxylate Transporter (1) mRNA (1) P-glycoprotein (1) p38 MAPK (2) Parasite (1) PSMA (1) Reactive Oxygen Species (ROS) (7) Reference Standards (35) Reverse Transcriptase (1) RSV (1) SARS-CoV (1) Thrombin (1) VSV (1) β-glucuronidase (2)
By Research Areas:	Cancer (10) Cardiovascular Disease (1) Endocrinology (1) Infection (9) Inflammation/Immunology (8) Metabolic Disease (3) Neurological Disease (8)
Click Chemistry:	Labeling and Fluorescence Imaging (5) Azide (2) Tetrazine (2)
Oligonucleotides:	mRNA (1) Reporter Genes (1)

125

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Targets Recommended: Fluorescent Dye

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D1533

RhoNox-1 Maximum Cited Publications 39 Publications Verification	Fluorescent Dye	Others
RhoNox-1 is a fluorescent probe for the specific detection of divalent iron ions, and when RhoNox-1 reacts with Fe ²⁺. RhoNox-1 can generate an irreversible orange (red) fluorescent product (Ex/Em：540/575 nm) . FeRhoNox-1 can enter the cell well, suitable for the detection of Fe ²⁺ in living cells, and tends to be localized in the Golgi apparatus .

HY-D1462

CellTracker Blue CMAC 5+ Cited Publications	Fluorescent Dye	Others
CellTracker Blue CMAC is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels .

HY-100041

Bromobimane 5+ Cited Publications Monobromobimane	Fluorescent Dye	Others
Bromobimane (Monobromobimane) is a nonfluorescent and converts into fluorescent products when reacts with thiols. Bromobimane has potential applications in labeling thiols .

HY-D0715

Fluorescamine 1 Publications Verification Ro 20-7234	Fluorescent Dye	Others
Fluorescamine is a spirocyclic compound that is non-fluorescent. Fluorescamine reacts rapidly with primary amine groups in proteins under alkaline conditions to generate products with strong fluorescence (Ex/Em: 390/475 nm). Fluorescamine can be used to detect amine-containing compounds, including amino acids, peptides, and proteins .

HY-W040143

2',7'-Dichlorofluorescein	Reactive Oxygen Species (ROS) Fluorescent Dye	Inflammation/Immunology
2',7'-Dichlorofluorescein is an important fluorescent product in the detection of oxidative stress and can be used to measure reactive oxygen species (ROS) (Ex=503 nm and Em=523 nm) .

HY-118135

4-Methylumbelliferyl-α-D-galactopyranoside 4MU-α-Gal	Fluorescent Dye	Others
4-Methylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal), a substrate for α-galactosidase A (GLA), is a blue pro-fluorogenic substrate. 4-Methylumbelliferyl-α-D-galactopyranoside forms two products, galactose and fluorescent 4MU, upon cleavage by GLA .

HY-130735

Janelia Fluor® 646, SE JF646, SE; JF646, NHS	Fluorescent Dye	Others
Janelia Fluor 646, SE (JF646, SE) is a red fluorescent dye can be used in cellular imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-134434

Z-Arg-Arg-AMC hydrochloride 1 Publications Verification	Cathepsin Fluorescent Dye	Others
Z-Arg-Arg-AMC hydrochloride is a highly selective fluorescent Cathepsin B substrate. Z-Arg-Arg-AMC hydrochloride can be hydrolyzed by Cathepsin B to produce a fluorescent product for enzyme activity detection .

HY-D0785

NBD-F 4-Fluoro-7-nitrobenzofurazan	Fluorescent Dye	Others
NBD-F (4-Fluoro-7-nitrobenzofurazan) is a pro-fluorescent reagent which is developed for amino acid analysis. NBD-F reacts with primary or secondary amines to produce a fluorescent product and used for analysis of amino acids and low molecular weight amines .

HY-D0073

2,3-Diaminonaphthalene	Fluorescent Dye	Others
2,3-Diaminonaphthalene is a fluorescent reagent used to detect selenium and nitric oxide (NO). 2,3-Diaminonaphthalene binds to selenium to form pyrazolene selenol, with excitation/emission maxima at 365 nm and 525 nm, respectively. 2,3-Diaminonaphthalene binds to NO2− to form the fluorescent product, 1-(H)-napthotriazole, with excitation/emission maxima at 360 nm and 440 nm, respectively .

HY-123645

Rhodamine B hydrazide 1 Publications Verification	Fluorescent Dye	Others
Rhodamine B hydrazide is a fluorescent derivative based on rhodamine B, containing the spirocyclic structure of Rhodamine B (HY-Y0016), which can be used to detect copper ions (Cu ²⁺), mercury ions, peroxynitrite, hydroxyl radicals and nitric oxide (NO) . Excitation/emission wavelength: Conventional detection: 510/578 nm. Sulfite detection: 554 nm absorption, 574 nm emission (due to the formation of Rhodamine B fluorescent product).

HY-P2528

Enhanced Green Fluorescent Protein (EGFP) (200-208)	Fluorescent Dye	Others
Enhanced Green Fluorescent Protein (EGFP) (200-208) is a marker gene product derived from the jellyfish Aequorea Victoria. Enhanced Green Fluorescent Protein (EGFP) (200-208) is a common reporter protein and is easy to detect .

HY-D0055

3-Cyano-7-ethoxycoumarin 1 Publications Verification	Cytochrome P450	Others
3-Cyano-7-ethoxycoumarin is a fluorescent cytochrome P-450 substrate that generates a blue fluorescent product upon enzymatic cleavage. 3-Cyano-7-ethoxycoumarin is used to detect the activity of mixed-function oxidases in isolated rat hepatocytes. 3-Cyano-7-ethoxycoumarin serves as a biological dye and indicator for research .

HY-D1506

Fl-DIBO	Fluorescent Dye	Others
Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference . Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W009938

Anthrone 1 Publications Verification Anthracen-9(10H)-one	Biochemical Assay Reagents	Others
Anthrone is an organic compound commonly used as a dye and intermediate. It can be used to make products such as pigments, dyes and fluorescent whitening agents, and is widely used in certain industrial production fields such as textile manufacturing, soap making and paper making. In addition, this compound is also used as a reagent and catalyst in some organic synthesis reactions.

HY-174497

eGFP mRNA	mRNA	Others
eGFP mRNA expresses green fluorescent protein derived from the jellyfish Aequorea victoria. eGFP is a commonly used direct-detection reporter gene in mammalian cell culture, which produces bright green fluorescence. This product is synthesized without modified nucleosides, with a Cap1 version cap analog at the 5' end and a 100nt PolyA tail at the 3' end. It can be used as a positive reference for IVT (in vitro transcription) or LNP delivery systems.

HY-D2869

Ac-H-FluNox	Fluorescent Dye Drug Intermediate	Others
Ac-H-FluNox is an acetylated cell-compatible prodrug of H-FluNox (HY-D2339). Ac-H-FluNox undergoes intracellular hydrolysis of its acetyl group by esterases to generate H-FluNox, which then undergoes a deoxygenation reaction with labile heme to form a fluorescent product. Ac-H-FluNox detects fluctuations of labile heme in living cells, acute labile heme release upon nitric oxide stimulation, and accumulation of labile heme following inhibition of heme export proteins .

HY-DY1030

RhoNox-1 (solution)	Fluorescent Dye	Others
RhoNox-1 (solution) is a fluorescent probe for the specific detection of divalent iron ions, and when RhoNox-1 reacts with Fe ²⁺. RhoNox-1 can generate an irreversible orange (red) fluorescent product (Ex/Em：540/575 nm). FeRhoNox-1 can enter the cell well, suitable for the detection of Fe ²⁺ in living cells, and tends to be localized in the Golgi apparatus . Solvent and concentration: DMSO: 5 mM

HY-W015590

2-Hydroxyphenylacetic acid	Drug Metabolite Fungal	Infection Metabolic Disease
2-Hydroxyphenylacetic acid is a metabolite of Phenylalanine and Tyrosine, as well as a product of the biotransformation of Phenylacetonitrile by marine fungi. 2-Hydroxyphenylacetic acid acts as a potential biomarker for food. 2-Hydroxyphenylacetic acid slightly induces the expression of green fluorescent protein. 2-Hydroxyphenylacetic acid is used in the research of phenylketonuria and related hyperphenylalaninemia .

HY-137855

4-Methylumbelliferyl sulfate potassium	Biochemical Assay Reagents	Others
4-Methylumbelliferyl sulfate (potassium), a fluorescent substrate, is commonly used to detect sulfatase activity in biochemical and biomedical research. It consists of a sulfate group attached to a fluorescent molecule, which can be cleaved by sulfatase enzymes. Upon cleavage, 4-Methylumbelliferyl sulfate releases a highly fluorescent product that can be detected using fluorescence microscopy or spectroscopy. The use of 4-Methylumbelliferyl sulfate as a substrate for sulfatase enzymes allows accurate detection and quantification of these enzymes in a variety of biological samples.

HY-160973

ELF97 phosphate ELFP	Biochemical Assay Reagents	Others
ELF97 phosphate (ELFP) is a phosphatase substrate, which can produced a fluorescent, water-insoluble product ELF97 alcohol after hydrolysis by phosphatases. ELF97 phosphate can be utilized to study and quantify the activity of extracellular phosphatases of algae in natural water .

HY-D0711R

Indocyanine green (Standard) Foxgreen (Standard); IC Green (Standard); Cardiogreen (Standard)	Fluorescent Dye Reference Standards	Others
Indocyanine green (Standard) is the analytical standard of Indocyanine green. This product is intended for research and analytical applications. Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .

HY-131029

Janelia Fluor® 646, Maleimide JF646, Maleimide	Fluorescent Dye	Others
Janelia Fluor® 646, Maleimide (JF646, Maleimide) is a red fluorescent dye that contains a maleimide group. JF646, Maleimide can be used in cellular imaging . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-131028

Janelia Fluor® 646 TFA JF646 TFA	Fluorescent Dye	Others
Janelia Fluor 646 TFA (JF646 TFA), a red fluorogenic fluorescent dye, can be used in the synthesis of Janelia Fluor 646 HaloTag and SNAP-Tag ligands. JF646 TFA is used in live cell imaging experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-114351

BODIPY FL hydrazide	Fluorescent Dye	Others
BODIPY FL Hydrazide is a green-fluorescent dye, BODIPY FL Hydrazide is reactive with aldehyde/ketone on polysaccharides and glycoproteins, yielding a reversible Schiff base product that can be transformed to a stable linkage using a reducing agent like sodium borohydride or sodium cyanoborohydride. (λ_ex=495 nm, λ_em=516 nm) .

HY-P4417

Ac-IEPD-AMC	Fluorescent Dye	Others
Ac-IEPD-AMC is a fluorogenic substrate for the determination of protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-P4419A

Boc-Asp(OBzl)-Pro-Arg-AMC acetate	Fluorescent Dye	Others
Boc-Asp(OBzl)-Pro-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC acetate undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-113033

Pentosidine	Others Biochemical Assay Reagents	Neurological Disease Metabolic Disease Inflammation/Immunology
Pentosidine is a fluorescent advanced glycation end product (AGE) and cross-linker. Pentosidine is a fluorescent cross-linked structure formed by lysine and arginine in sugar oxidation reactions, and it is commonly found in collagen, skin, bone, lens and plasma proteins . Pentosidine is used in research related to type 1 diabetes, brown cataracts, rheumatoid arthritis, atherosclerosis and neurodegenerative diseases .

HY-W011618

N-(9-Acridinyl)maleimide	Fluorescent Dye	Others
N-(9-Acridinyl)maleimide is a maleimide type fluorescent thiol reagent. N-(9-Acridinyl)maleimide shows no substantial fluorescence but its coupling products with thiol compounds exhibit strong blue fluorescence. N-(9-Acridinyl)maleimide is used for fluorometrical analysis of cysteine and glutathione .

HY-131026

Janelia Fluor® 635, SE JF635, SE; JF635, NHS	Fluorescent Dye	Others
Janelia Fluor 635, SE (JF635, SE) is a red fluorogenic fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. JF635, SE can be used for live cell imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-137249

Resorufin-β-D-galactopyranoside	Biochemical Assay Reagents	Others
Resorufin-β-D-galactopyranoside is a commonly used substrate in various biochemical assays to measure the activity of β-galactosidase, an important enzyme involved in lactose metabolism and regulation of gene expression. Resorufin-β-D-galactopyranoside has unique chemical properties and can be hydrolyzed by β-galactosidase to form a red fluorescent product called resorufin. This makes it a useful tool for detecting and quantifying β-galactosidase activity in biological samples such as bacteria or mammalian cells.

HY-147889

BBR-BODIPY	Apoptosis Caspase Bcl-2 Family	Others
BBR-BODIPY is a fluorescent probe that allows screening its interaction with the targeted cells. BBR-BODIPY induces apoptosis and changes the expression of apoptosis-related proteins .

HY-111391R

Resazurin sodium (Standard) Diazoresorcinol sodium (Standard)	Reference Standards Bacterial	Others
Resazurin (sodium) (Standard) is the analytical standard of Resazurin (sodium). This product is intended for research and analytical applications. Resazurin sodium (Diazoresorcinol sodium) is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin.

HY-P4406

Abz-AGLA-Nba 1 Publications Verification	Fluorescent Dye	Others
Abz-AGLA-Nba is a fluorogenic substrate for the determination of protease activity. Abz-AGLA-Nba is hydrolyzed to release aminoacyl benzimide (Abz-AGLA) and 2-naphthylaminoacyl (Nba). The product Abz-AGLA produced by this hydrolysis reaction is fluorescent under ultraviolet light and can emit a fluorescent signal .

HY-Y0016R

Rhodamine B (Standard) Basic Violet 10 (Standard); Brilliant Pink B (Standard); Rhodamine O (Standard); Tetraethylrhodamine (Standard)	Fluorescent Dye Reference Standards	Others
Rhodamine B (Standard) is the analytical standard of Rhodamine B. This product is intended for research and analytical applications. Rhodamine B is a staining fluorescent dye, commonly used for dyeing textiles, paper, soap, leather, and agents.

HY-79602

p-Toluenesulfonamide	Biochemical Assay Reagents Drug Derivative Drug Intermediate	Others
p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .

HY-DY1041

CellTracker Blue CMAC (solution)	Fluorescent Dye	Others
CellTracker Blue CMAC (solution) is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels . Solvent and concentration: DMSO: 10 mM

HY-N2011R

Octyl gallate (Standard) n-Octyl gallate (Standard); Stabilizer GA 8 (Standard)	VSV Reference Standards Bacterial HSV Influenza Virus Reactive Oxygen Species (ROS)	Infection
Octyl gallate (Standard) is the analytical standard of Octyl gallate. This product is intended for research and analytical applications. Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity . Octyl gallate (Progallin O) shows selective and sensitive fluorescent property . Octyl gallate shows a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV) and poliovirus .

HY-129887

Fluorescein diphosphate tetraammonium	Fluorescent Dye	Others
Fluorescein diphosphate tetraammonium is a fluorescent dye, it can be used as a fluorogenic substrate and generats fluorescein as a fluorescent product .

HY-P4417A

Ac-IEPD-AMC TFA	Fluorescent Dye	Others
Ac-IEPD-AMC TFA is a fluorescent substrate used to measure protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC fluoresces under UV light irradiation and can emit fluorescent signals .

HY-P4323A

Boc-Gln-Arg-Arg-AMC acetate	Fluorescent Dye	Others
Boc-Gln-Arg-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-D1523

Z-Arg-Arg-4MβNA triacetate	Cathepsin	Others
Z-Arg-Arg-4MβNA triacetate is a cathepsin B-specific substrate and can produce fluorescent end product 4MβNA (λ_ex = 355 nm, λ_em = 430 nm) .

HY-131022

Janelia Fluor® 549 TFA JF549 TFA	Fluorescent Dye	Others
Janelia Fluor® 549 TFA (JF549 TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D0309R

Rhodamine 6G (Standard) Basic Red 1 (Standard)	Fluorescent Dye Reference Standards	Cancer
Rhodamine 6G (Standard) is the analytical standard of Rhodamine 6G. This product is intended for research and analytical applications. Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

HY-D1377

Citrulline-specific probe-rhodamine hydrate	Fluorescent Dye	Others
Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis .

HY-P0128F1

FITC-β-Ala-β-Amyloid (25-35）	Amyloid-β	Neurological Disease
FITC-β-Ala-β-Amyloid (25-35) is a fluorescent product labeled by FITC that can be used in Alzheimer's disease research .

HY-P4406A

Abz-AGLA-Nba TFA	Fluorescent Dye	Others
Abz-AGLA-Nba TFA is a fluorogenic substrate for the determination of protease activity. Abz-AGLA-Nba TFA is hydrolyzed to release aminoacyl benzimide (Abz-AGLA) and 2-naphthylaminoacyl (Nba). The product Abz-AGLA produced by this hydrolysis reaction is fluorescent under ultraviolet light and can emit a fluorescent signal .

HY-145385

Coelenteramide	Fluorescent Dye	Others
Coelenteramide is a oxidative product of Coelenterazine (HY-18743). Coelenteramide can form a complex with apoAequorin/Ca ²⁺, which is known as blue fluorescent protein (BFP) and shows continuous weak luminescence with Coelenterazine like a luciferase. Coelenteramide can be used as an imaging agent .

HY-79602S1

p-Toluenesulfonamide-15N	Isotope-Labeled Compounds Biochemical Assay Reagents Drug Derivative Drug Intermediate	Others
p-Toluenesulfonamide- ¹⁵N is the ¹⁵N-labeled p-Toluenesulfonamide (HY-79602). p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .

HY-N0188R

Esculin (Standard)	Reference Standards p38 MAPK	Inflammation/Immunology Cancer
Esculin (Standard) is the analytical standard of Esculin. This product is intended for research and analytical applications. Esculin is a fluorescent coumarin glucoside, the active ingredient in ash bark. Esculin has antidiabetic effects, improves cognitive impairment in experimental diabetic nephropathy (DN) via the MAPK signaling pathway, and exerts antioxidant stress and anti-inflammatory effects. Esculin also has anticancer, antibacterial, antiviral, neuroprotective, antithrombotic, and therapeutic properties for eye diseases .

Cat. No.	Product Name	Type

HY-D1533

RhoNox-1 Maximum Cited Publications 39 Publications Verification	Fluorescent Dyes
RhoNox-1 is a fluorescent probe for the specific detection of divalent iron ions, and when RhoNox-1 reacts with Fe ²⁺. RhoNox-1 can generate an irreversible orange (red) fluorescent product (Ex/Em：540/575 nm) . FeRhoNox-1 can enter the cell well, suitable for the detection of Fe ²⁺ in living cells, and tends to be localized in the Golgi apparatus .

HY-D1462

CellTracker Blue CMAC

5+ Cited Publications

Fluorescent Dyes

CellTracker Blue CMAC is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels .

HY-100041

Bromobimane 5+ Cited Publications Monobromobimane	Fluorescent Dyes
Bromobimane (Monobromobimane) is a nonfluorescent and converts into fluorescent products when reacts with thiols. Bromobimane has potential applications in labeling thiols .

HY-D0715

Fluorescamine 1 Publications Verification Ro 20-7234	Fluorescent Dyes
Fluorescamine is a spirocyclic compound that is non-fluorescent. Fluorescamine reacts rapidly with primary amine groups in proteins under alkaline conditions to generate products with strong fluorescence (Ex/Em: 390/475 nm). Fluorescamine can be used to detect amine-containing compounds, including amino acids, peptides, and proteins .

HY-W040143

2',7'-Dichlorofluorescein	Fluorescent Dyes
2',7'-Dichlorofluorescein is an important fluorescent product in the detection of oxidative stress and can be used to measure reactive oxygen species (ROS) (Ex=503 nm and Em=523 nm) .

HY-130735

Janelia Fluor® 646, SE JF646, SE; JF646, NHS	Fluorescent Dyes
Janelia Fluor 646, SE (JF646, SE) is a red fluorescent dye can be used in cellular imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D0785

NBD-F 4-Fluoro-7-nitrobenzofurazan	Fluorescent Dyes
NBD-F (4-Fluoro-7-nitrobenzofurazan) is a pro-fluorescent reagent which is developed for amino acid analysis. NBD-F reacts with primary or secondary amines to produce a fluorescent product and used for analysis of amino acids and low molecular weight amines .

HY-D0073

2,3-Diaminonaphthalene

Fluorescent Dyes

2,3-Diaminonaphthalene is a fluorescent reagent used to detect selenium and nitric oxide (NO). 2,3-Diaminonaphthalene binds to selenium to form pyrazolene selenol, with excitation/emission maxima at 365 nm and 525 nm, respectively. 2,3-Diaminonaphthalene binds to NO2− to form the fluorescent product, 1-(H)-napthotriazole, with excitation/emission maxima at 360 nm and 440 nm, respectively .

HY-123645

Rhodamine B hydrazide

1 Publications Verification

Fluorescent Dyes

Rhodamine B hydrazide is a fluorescent derivative based on rhodamine B, containing the spirocyclic structure of Rhodamine B (HY-Y0016), which can be used to detect copper ions (Cu ²⁺), mercury ions, peroxynitrite, hydroxyl radicals and nitric oxide (NO) .
Excitation/emission wavelength:
Conventional detection: 510/578 nm.
Sulfite detection: 554 nm absorption, 574 nm emission (due to the formation of Rhodamine B fluorescent product).

HY-D0055

3-Cyano-7-ethoxycoumarin 1 Publications Verification	Fluorescent Dyes
3-Cyano-7-ethoxycoumarin is a fluorescent cytochrome P-450 substrate that generates a blue fluorescent product upon enzymatic cleavage. 3-Cyano-7-ethoxycoumarin is used to detect the activity of mixed-function oxidases in isolated rat hepatocytes. 3-Cyano-7-ethoxycoumarin serves as a biological dye and indicator for research .

HY-D1506

Fl-DIBO

Fluorescent Dyes

Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference . Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D2869

Ac-H-FluNox

Fluorescent Dyes

Ac-H-FluNox is an acetylated cell-compatible prodrug of H-FluNox (HY-D2339). Ac-H-FluNox undergoes intracellular hydrolysis of its acetyl group by esterases to generate H-FluNox, which then undergoes a deoxygenation reaction with labile heme to form a fluorescent product. Ac-H-FluNox detects fluctuations of labile heme in living cells, acute labile heme release upon nitric oxide stimulation, and accumulation of labile heme following inhibition of heme export proteins .

HY-131027

Janelia Fluor® 646, Azide

JF646, Azide

Fluorescent Dyes

Janelia Fluor 646, Azide (JF646, Azide) is a red fluorogenic fluorescent dye containing a click chemistry group Azide. Janelia Fluor 646, Azide can be used for live-cell imaging experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-DY1030

RhoNox-1 (solution)

Fluorescent Dyes

RhoNox-1 (solution) is a fluorescent probe for the specific detection of divalent iron ions, and when RhoNox-1 reacts with Fe ²⁺. RhoNox-1 can generate an irreversible orange (red) fluorescent product (Ex/Em：540/575 nm). FeRhoNox-1 can enter the cell well, suitable for the detection of Fe ²⁺ in living cells, and tends to be localized in the Golgi apparatus .
Solvent and concentration: DMSO: 5 mM

HY-D1808

Vari Fluor 488-Streptavidin

1 Publications Verification

Fluorescent Dyes

Vari Fluor 488-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=490 nm/515 nm.
Product Concentration: 0.8 mg/mL

HY-D1805

Vari Fluor 647-Streptavidin

Fluorescent Dyes

Vari Fluor 647-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=650 nm/665 nm.
Product Concentration: 0.8 mg/mL

HY-D1078

5(6)-Carboxy-2',7'-dichlorofluorescein diacetate

Fluorescent Dyes

5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate is a fluorescein-based reactive oxygen species (ROS) probe and also a MRP2 substrate. 5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate serves as a substrate for intracellular esterases, which cleave its acetate groups to generate a fluorescent product capable of detecting intracellular ROS. 5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate is ATP-dependent and is transported via a single MRP2 binding site; it competes with LTC₄ for MRP2 binding sites and inhibits MRP2-mediated LTC₄ transport (Ex/Em = 496/525 nm) .

HY-D0711R

Indocyanine green (Standard) Foxgreen (Standard); IC Green (Standard); Cardiogreen (Standard)	Fluorescent Dyes
Indocyanine green (Standard) is the analytical standard of Indocyanine green. This product is intended for research and analytical applications. Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .

HY-131029

Janelia Fluor® 646, Maleimide JF646, Maleimide	Fluorescent Dyes
Janelia Fluor® 646, Maleimide (JF646, Maleimide) is a red fluorescent dye that contains a maleimide group. JF646, Maleimide can be used in cellular imaging . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-131028

Janelia Fluor® 646 TFA JF646 TFA	Fluorescent Dyes
Janelia Fluor 646 TFA (JF646 TFA), a red fluorogenic fluorescent dye, can be used in the synthesis of Janelia Fluor 646 HaloTag and SNAP-Tag ligands. JF646 TFA is used in live cell imaging experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D1191

SYBR green I chloride

3 Publications Verification

Fluorescent Dyes

SYBR Green I chloride is a highly sensitive fluorescent nucleic acid dye that binds specifically to the minor groove of double-stranded DNA or intercalates between base pairs. SYBR Green I chloride exhibits weak fluorescence in the unbound state but emits bright fluorescence upon binding, and it preferentially binds to large-fragment DNA and DNA with high G+C content. SYBR Green I chloride is suitable for real-time PCR technology; its fluorescence intensity correlates with the amount and size of amplification products, enabling accurate quantification of gene expression and discrimination of amplicons via melting curve analysis without additional post-processing. SYBR Green I chloride is widely used in preclinical in vitro nucleic acid detection .

HY-114351

BODIPY FL hydrazide	Fluorescent Dyes
BODIPY FL Hydrazide is a green-fluorescent dye, BODIPY FL Hydrazide is reactive with aldehyde/ketone on polysaccharides and glycoproteins, yielding a reversible Schiff base product that can be transformed to a stable linkage using a reducing agent like sodium borohydride or sodium cyanoborohydride. (λ_ex=495 nm, λ_em=516 nm) .

HY-W011618

N-(9-Acridinyl)maleimide	Fluorescent Dyes
N-(9-Acridinyl)maleimide is a maleimide type fluorescent thiol reagent. N-(9-Acridinyl)maleimide shows no substantial fluorescence but its coupling products with thiol compounds exhibit strong blue fluorescence. N-(9-Acridinyl)maleimide is used for fluorometrical analysis of cysteine and glutathione .

HY-131026

Janelia Fluor® 635, SE JF635, SE; JF635, NHS	Fluorescent Dyes
Janelia Fluor 635, SE (JF635, SE) is a red fluorogenic fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. JF635, SE can be used for live cell imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-138659

Janelia Fluor® 646, Tetrazine

JF646, Tetrazine

Fluorescent Dyes

Janelia Fluor 646, Tetrazine (JF646, Tetrazine) a red fluorescent dye that contains a tetrazine group. JF646, Tetrazine can be used in cellular imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-131021

Janelia Fluor® 549, Azide

1 Publications Verification

JF549, Azide

Fluorescent Dyes

Janelia Fluor? 549, Azide (JF549, Azide) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor? products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-D1807

Vari Fluor 555-Streptavidin

Fluorescent Dyes

Vari Fluor 555-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=555 nm/565 nm.
Product Concentration: 0.8 mg/mL

HY-147889

BBR-BODIPY	Fluorescent Dyes
BBR-BODIPY is a fluorescent probe that allows screening its interaction with the targeted cells. BBR-BODIPY induces apoptosis and changes the expression of apoptosis-related proteins .

HY-111391R

Resazurin sodium (Standard) Diazoresorcinol sodium (Standard)	Fluorescent Dyes
Resazurin (sodium) (Standard) is the analytical standard of Resazurin (sodium). This product is intended for research and analytical applications. Resazurin sodium (Diazoresorcinol sodium) is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin.

HY-Y0016R

Rhodamine B (Standard) Basic Violet 10 (Standard); Brilliant Pink B (Standard); Rhodamine O (Standard); Tetraethylrhodamine (Standard)	Fluorescent Dyes
Rhodamine B (Standard) is the analytical standard of Rhodamine B. This product is intended for research and analytical applications. Rhodamine B is a staining fluorescent dye, commonly used for dyeing textiles, paper, soap, leather, and agents.

HY-DY1041

CellTracker Blue CMAC (solution)

Fluorescent Dyes

CellTracker Blue CMAC (solution) is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels .
Solvent and concentration: DMSO: 10 mM

HY-131030

Janelia Fluor® 669, SE JF669, SE; JF669, NHS	Fluorescent Dyes
Janelia Fluor 669, SE (JF669, SE), a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm) . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D1632

4-MU-α-GlcNS sodium

Fluorescent Dyes

4-MU-α-GlcNS sodium is a fluorogenic substrate of heparin sulphamidase, is desulfurized into 4-MU-α-GlcNH₂. 4-MU-α-GlcNH₂ can liberate 4-methylumbelliferone (4-MU, fluorescent product) via α-glucosaminidase catalysis, with the emission wavelength maxima of 445-454 nm. 4-MU-α-GlcNS sodium can be used to heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders researches .

HY-D1806

Vari Fluor 594-Streptavidin

1 Publications Verification

Fluorescent Dyes

Vari Fluor 594-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=590 nm/617 nm.
Product Concentration: 0.8 mg/mL

HY-129887

Fluorescein diphosphate tetraammonium	Fluorescent Dyes
Fluorescein diphosphate tetraammonium is a fluorescent dye, it can be used as a fluorogenic substrate and generats fluorescein as a fluorescent product .

HY-D1523

Z-Arg-Arg-4MβNA triacetate	Fluorescent Dyes
Z-Arg-Arg-4MβNA triacetate is a cathepsin B-specific substrate and can produce fluorescent end product 4MβNA (λ_ex = 355 nm, λ_em = 430 nm) .

HY-131022

Janelia Fluor® 549 TFA JF549 TFA	Fluorescent Dyes
Janelia Fluor® 549 TFA (JF549 TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D0309R

Rhodamine 6G (Standard)

Basic Red 1 (Standard)

Fluorescent Dyes

Rhodamine 6G (Standard) is the analytical standard of Rhodamine 6G. This product is intended for research and analytical applications. Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

HY-D1377

Citrulline-specific probe-rhodamine hydrate

Fluorescent Dyes

Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis .

HY-D1809

Vari Fluor 405-Streptavidin

Fluorescent Dyes

Vari Fluor 405-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=405 nm/431 nm.
Product Concentration: 0.8 mg/mL

HY-D1804

Vari Fluor 680-Streptavidin

Fluorescent Dyes

Vari Fluor 680-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=680 nm/701 nm.
Product Concentration: 0.8 mg/mL

HY-145385

Coelenteramide	Fluorescent Dyes
Coelenteramide is a oxidative product of Coelenterazine (HY-18743). Coelenteramide can form a complex with apoAequorin/Ca ²⁺, which is known as blue fluorescent protein (BFP) and shows continuous weak luminescence with Coelenterazine like a luciferase. Coelenteramide can be used as an imaging agent .

HY-131025

Janelia Fluor® 585, SE

JF585, SE; JF585, NHS

Fluorescent Dyes

Janelia Fluor 585, SE (JF585, SE) is an orange fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. Janelia Fluor 585, SE can be used immediately for structured illumination (SIM) and stimulated emission depletion (STED) imaging and could be converted to photoactivatable derivative for single-molecule localization microscopy (SMLM) experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D0251R

Fluorescein (Standard)

Uranine (Standard)

Fluorescent Dyes

Fluorescein (Standard) is the analytical standard of Fluorescein. This product is intended for research and analytical applications. Fluorescein (Uranine) is widely used as a fluorescent tracer in medicinal and biological applications and tumor infected tissues tracer. Fluorescein (Uranine) is a representative green fluorophore that has been widely used as a scaffold of practically useful green fluorescent probes .

HY-131024

Janelia Fluor® 549, Tetrazine JF549, Tetrazine	Fluorescent Dyes
Janelia Fluor® 549, Tetrazine (JF549, Tetrazine) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-131023

Janelia Fluor® 549, Maleimide TFA JF549, Maleimide TFA	Fluorescent Dyes
Janelia Fluor® 549, Maleimide TFA (JF549, Maleimide TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D2338

PMBD

Fluorescent Dyes

PMBD is a lysosome (Lyso)-targeting fluorescent probe. PMBD selectively and sensitively detects endogenous N-acylethanolamine amidase (NAAA), allowing real-time visual monitoring of endogenous NAAA in living cells. PMBD has a maximum absorption peak at 350 nm. After the metabolism of NAAA, the maximum absorption peak of the product AMBD shifts red to 450 nm, and a significant fluorescence emission signal appears at 550 nm .

HY-D0310R

Fluorescent Brightener 135 (Standard)	Fluorescent Dyes
Fluorescent Brightener 135 (Standard) is the analytical standard of Fluorescent Brightener 135. This product is intended for research and analytical applications. Fluorescent Brightener 135 is an optical brightener dye.

HY-D0715R

Fluorescamine (Standard)

Ro 20-7234 (Standard)

Fluorescent Dyes

Fluorescamine (Standard) is the analytical standard of Fluorescamine (HY-D0715). This product is intended for research and analytical applications. Fluorescamine is a spirocyclic compound that is non-fluorescent. Fluorescamine reacts rapidly with primary amine groups in proteins under alkaline conditions to generate products with strong fluorescence (Ex/Em : 390/475 nm). Fluorescamine can be used to detect amine-containing compounds, including amino acids, peptides, and proteins .

HY-D0113

7-Hydroxy-4-methyl-2(1H)-quinolone	Fluorescent Dyes
7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b) is a fluorescent hydroxylated product. 7-Hydroxy-4-methyl-2(1H)-quinolone can be used for detecting hydroxyl radicals of DNA damage .

Cat. No.	Product Name	Type

HY-W009938

Anthrone 1 Publications Verification Anthracen-9(10H)-one	Biochemical Assay Reagents
Anthrone is an organic compound commonly used as a dye and intermediate. It can be used to make products such as pigments, dyes and fluorescent whitening agents, and is widely used in certain industrial production fields such as textile manufacturing, soap making and paper making. In addition, this compound is also used as a reagent and catalyst in some organic synthesis reactions.

HY-D1078

5(6)-Carboxy-2',7'-dichlorofluorescein diacetate

Biochemical Assay Reagents

HY-137855

4-Methylumbelliferyl sulfate potassium

Biochemical Assay Reagents

4-Methylumbelliferyl sulfate (potassium), a fluorescent substrate, is commonly used to detect sulfatase activity in biochemical and biomedical research. It consists of a sulfate group attached to a fluorescent molecule, which can be cleaved by sulfatase enzymes. Upon cleavage, 4-Methylumbelliferyl sulfate releases a highly fluorescent product that can be detected using fluorescence microscopy or spectroscopy. The use of 4-Methylumbelliferyl sulfate as a substrate for sulfatase enzymes allows accurate detection and quantification of these enzymes in a variety of biological samples.

HY-137249

Resorufin-β-D-galactopyranoside

Biochemical Assay Reagents

Resorufin-β-D-galactopyranoside is a commonly used substrate in various biochemical assays to measure the activity of β-galactosidase, an important enzyme involved in lactose metabolism and regulation of gene expression. Resorufin-β-D-galactopyranoside has unique chemical properties and can be hydrolyzed by β-galactosidase to form a red fluorescent product called resorufin. This makes it a useful tool for detecting and quantifying β-galactosidase activity in biological samples such as bacteria or mammalian cells.

HY-79602

p-Toluenesulfonamide	Biochemical Assay Reagents
p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .

HY-W283888

5-Bromo-4-chloro-1H-indol-3-yl nonanoate	Biochemical Assay Reagents
5-Bromo-4-chloro-1H-indol-3-yl nonanoate is a fluorescent substrate used to detect enzymes. The substrate reacts with various enzymes to produce a fluorescent product, which has been shown to be active against β-galactosidase, α-chymotrypsin, and β-glucuronidase.

HY-79602R

p-Toluenesulfonamide (Standard)

Biochemical Assay Reagents

p-Toluenesulfonamide (Standard) is the analytical standard of p-Toluenesulfonamide (HY-79602). This product is intended for research and analytical applications. p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .

HY-W012669R

Phthalaldehyde (Standard) Phthaldialdehyde (Standard)	Biochemical Assay Reagents
Phthalaldehyde (Standard) is the analytical standard of Phthalaldehyde. This product is intended for research and analytical applications. Phthalaldehyde is a biochemical assay reagent, which modifies the amino acid and measure the derivative through HPLC. Phthalaldehyde forms a fluorescent compound with α-amino group .

Cat. No.	Product Name	Target	Research Area

HY-134434

Z-Arg-Arg-AMC hydrochloride 1 Publications Verification	Cathepsin Fluorescent Dye	Others
Z-Arg-Arg-AMC hydrochloride is a highly selective fluorescent Cathepsin B substrate. Z-Arg-Arg-AMC hydrochloride can be hydrolyzed by Cathepsin B to produce a fluorescent product for enzyme activity detection .

HY-P2528

Enhanced Green Fluorescent Protein (EGFP) (200-208)	Fluorescent Dye	Others
Enhanced Green Fluorescent Protein (EGFP) (200-208) is a marker gene product derived from the jellyfish Aequorea Victoria. Enhanced Green Fluorescent Protein (EGFP) (200-208) is a common reporter protein and is easy to detect .

HY-P4417

Ac-IEPD-AMC	Fluorescent Dye	Others
Ac-IEPD-AMC is a fluorogenic substrate for the determination of protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-P4419A

Boc-Asp(OBzl)-Pro-Arg-AMC acetate	Fluorescent Dye	Others
Boc-Asp(OBzl)-Pro-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC acetate undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-P4406

Abz-AGLA-Nba 1 Publications Verification	Fluorescent Dye	Others
Abz-AGLA-Nba is a fluorogenic substrate for the determination of protease activity. Abz-AGLA-Nba is hydrolyzed to release aminoacyl benzimide (Abz-AGLA) and 2-naphthylaminoacyl (Nba). The product Abz-AGLA produced by this hydrolysis reaction is fluorescent under ultraviolet light and can emit a fluorescent signal .

HY-P4417A

Ac-IEPD-AMC TFA	Fluorescent Dye	Others
Ac-IEPD-AMC TFA is a fluorescent substrate used to measure protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC fluoresces under UV light irradiation and can emit fluorescent signals .

HY-P4323A

Boc-Gln-Arg-Arg-AMC acetate	Fluorescent Dye	Others
Boc-Gln-Arg-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-P0128F1

FITC-β-Ala-β-Amyloid (25-35）	Amyloid-β	Neurological Disease
FITC-β-Ala-β-Amyloid (25-35) is a fluorescent product labeled by FITC that can be used in Alzheimer's disease research .

HY-P4406A

Abz-AGLA-Nba TFA	Fluorescent Dye	Others
Abz-AGLA-Nba TFA is a fluorogenic substrate for the determination of protease activity. Abz-AGLA-Nba TFA is hydrolyzed to release aminoacyl benzimide (Abz-AGLA) and 2-naphthylaminoacyl (Nba). The product Abz-AGLA produced by this hydrolysis reaction is fluorescent under ultraviolet light and can emit a fluorescent signal .

HY-P4443

Ac-GAK-AMC	Fluorescent Dye	Others
Ac-GAK-AMC is a fluorescent substrate that can be used to measure protease activity. AMC (7-amino-4-methylcoumarin) is a fluorescent group. In the presence of protease, the protease will hydrolyze Ac-GAK-AMC into a fluorescent product .

HY-P1388F

FITC-Ahx-β-Amyloid (1-42), (rat/mouse) tris FITC-Ahx-Amyloid β-peptide (1-42) (rat/mouse) tris	Amyloid-β	Neurological Disease
FITC-Ahx-β-Amyloid (1-42), (rat/mouse) (tris) is a fluorescently labeled (FITC) form of β-Amyloid (1-42), (rat/mouse) (HY-P1388), which can be used in Alzheimer's disease-related research, such as aggregation, fiber formation, cellular uptake or imaging experiments. This product is provided in the form of Tris salt.

HY-P4465

Gly-Arg-pNA	Fluorescent Dye	Others
Gly-Arg-pNA is a fluorogenic substrate for the measurement of protease activity. Gly-Arg-pNA undergoes hydrolysis and releases the fluorescent product p-nitroaniline. p-nitroaniline is in a fluorescent state under ultraviolet light irradiation and can emit a fluorescent signal .

HY-P4408

Ac-Arg-Gly-Lys-AMC	Fluorescent Dye	Others
Ac-Arg-Gly-Lys-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Arg-Gly-Lys-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-P4323

Boc-Gln-Arg-Arg-AMC	Fluorescent Dye	Others
Boc-Gln-Arg-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-P4416

Ac-Gly-Ala-Lys(Ac)-AMC	Fluorescent Dye	Others
Ac-Gly-Ala-Lys(Ac)-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Gly-Ala-Lys(Ac)-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-P4404

Abz-GIVRAK(Dnp)	Cathepsin	Others
Abz-GIVRAK(Dnp) is the most efficient substrate for cathepsin B and is highly selective for this enzyme among lysosomal cysteine proteases. After Abz-GIVRAK(Dnp) is hydrolyzed, aminoacylbenziminosulfosuccinic acid (Abz-SAS) is released, and dinitrobenzoyl (Dnp) is also released. The product of this hydrolysis reaction, Abz-SAS, is fluorescent under ultraviolet light and can emit a fluorescent signal .

HY-P4419

Boc-Asp(OBzl)-Pro-Arg-AMC	Fluorescent Dye	Others
Boc-Asp(OBzl)-Pro-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). The excitation and emission wavelengths are 351 nm and 430 nm, respectively .

HY-P5295

Cy3-Ova (323-339)	Fluorescent Dye	Others
Cy3-Ova (323-339) is an Cy3 labled OVA Peptide (323-339) (HY-P0286). Cy3 is a fluorescent dye belonging to the Cyanine family and is a fluorescent light product of Cy5. Cyanine is commonly used in fluorescence microscopy, cell imaging, and molecular biology experiments. OVA Peptide (323-339) represents the T and B cell epitopes of ovalbumin (OVA). OVA Peptide (323-339) has limited immunogenic efficacy in activating OVA-sensitized and attacked mouse spleen cells .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W015590

2-Hydroxyphenylacetic acid	Structural Classification Monophenols Ketones, Aldehydes, Acids Disease markers Phenols Endocrine diseases Nervous System Disorder Endogenous metabolite Source Classification	Drug Metabolite Fungal
2-Hydroxyphenylacetic acid is a metabolite of Phenylalanine and Tyrosine, as well as a product of the biotransformation of Phenylacetonitrile by marine fungi. 2-Hydroxyphenylacetic acid acts as a potential biomarker for food. 2-Hydroxyphenylacetic acid slightly induces the expression of green fluorescent protein. 2-Hydroxyphenylacetic acid is used in the research of phenylketonuria and related hyperphenylalaninemia .

HY-113033

Pentosidine	Structural Classification Natural Products Disease markers Endogenous metabolite Source Classification	Others Biochemical Assay Reagents
Pentosidine is a fluorescent advanced glycation end product (AGE) and cross-linker. Pentosidine is a fluorescent cross-linked structure formed by lysine and arginine in sugar oxidation reactions, and it is commonly found in collagen, skin, bone, lens and plasma proteins . Pentosidine is used in research related to type 1 diabetes, brown cataracts, rheumatoid arthritis, atherosclerosis and neurodegenerative diseases .

HY-N2011R

Octyl gallate (Standard) n-Octyl gallate (Standard); Stabilizer GA 8 (Standard)	Structural Classification Paeonia lactiflora Pall. Phenols Polyphenols Plants Paeoniaceae Source Classification	VSV Reference Standards Bacterial HSV Influenza Virus Reactive Oxygen Species (ROS)
Octyl gallate (Standard) is the analytical standard of Octyl gallate. This product is intended for research and analytical applications. Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity . Octyl gallate (Progallin O) shows selective and sensitive fluorescent property . Octyl gallate shows a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV) and poliovirus .

HY-N0188R

Esculin (Standard)	Structural Classification Monophenols other families Coumarins Phenols Phenylpropanoids Plants Source Classification	Reference Standards p38 MAPK
Esculin (Standard) is the analytical standard of Esculin. This product is intended for research and analytical applications. Esculin is a fluorescent coumarin glucoside, the active ingredient in ash bark. Esculin has antidiabetic effects, improves cognitive impairment in experimental diabetic nephropathy (DN) via the MAPK signaling pathway, and exerts antioxidant stress and anti-inflammatory effects. Esculin also has anticancer, antibacterial, antiviral, neuroprotective, antithrombotic, and therapeutic properties for eye diseases .

HY-N1181R

Tamarixetin (Standard) 4'-O-Methyl Quercetin (Standard)	Flavonols Structural Classification Flavonoids Tamaricaceae Tamarix chinensis Lour. Phenols Polyphenols Plants Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite ClpP Bacterial Apoptosis Akt Interleukin Related COX JNK p38 MAPK Reactive Oxygen Species (ROS)
Tamarixetin (Standard) is the analytical standard of Tamarixetin. This product is intended for research and analytical applications. Tamarixetin (4'-O-Methyl Quercetin) is an orally active natural flavonoid derivative of quercetin and caseinolytic protease p (ClpP) inhibitor with anti-inflammatory, antioxidant and antitumor effects. Tamarixetin inhibits the hydrolytic activity of ClpP to the fluorescent substrate Suc-LY-AMC with an IC₅₀ of 49.73 μM, which can be used for the study of Staphylococcus aureus infection. Tamarixetin inhibits tumor cell growth, induces apoptosis, and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways .

HY-121271

Kadsurin	Classification of Application Fields Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Inflammation/Immunology Schisandra chinensis (Turcz.) Baill. Source Classification	Others
Kadsurin, a natural compound from the stems of Kadsura heteroclita (Schizandraceae), results in significant decreases of CCL₄- induced lipid-peroxidation products, such as thiobarbituric acid reactive substances (TBA-RS), conjugated dienes and fluorescent products in the liver of mice .

HY-Y1309R

1-Naphthol (Standard) Furro ER (Standard); NSC 9586 (Standard); Nako TRB (Standard)	Structural Classification Monophenols Phenols Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
1-Naphthol (Standard) is the analytical standard of 1-Naphthol. This product is intended for research and analytical applications. 1-naphthol is an excited state proton transfer (ESPT) fluorescent molecular probe.

HY-N7131R

Coumarin 6 (Standard)	Alkaloids Structural Classification Umbelliferae Plants Indole Alkaloids Ambrosia hispida Source Classification	Fluorescent Dye Reference Standards
Coumarin 6 (Standard) is the analytical standard of Coumarin 6 (HY-N7131). This product is intended for research and analytical applications. Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λexc=450 nm, λem=505 nm) .

HY-76217

2,5-Furandicarboxaldehyde 2,5-Diformylfuran	Structural Classification Natural Products Animals Source Classification	Drug Derivative
2,5-Furandicarboxaldehyde (2,5-Diformylfuran), a furan derivative, is a volatile organic compound. 2,5-Furandicarboxaldehyde the aerobic oxidation product of 5-Hydroxymethylfurfural (HY-Y0051), and can be used in organic synthesis and functional polymer manufacture, such as fluorescent material, surfactants, and vitrimer .

HY-W091541R

4-Hydroxy-1H-indole-3-carbaldehyde (Standard) 4-Hydroxyindole-3-carboxaldehyde (Standard)	Alkaloids Structural Classification Monophenols Capparis spinosa L. Phenols Capparidaceae Plants Indole Alkaloids Source Classification	Endogenous Metabolite Reference Standards
4-Hydroxy-1H-indole-3-carbaldehyde (Standard) is the analytical standard of 4-Hydroxy-1H-indole-3-carbaldehyde (HY-W091541). This product is intended for research and analytical applications. 4-Hydroxy-1H-indole-3-carbaldehyde (4-Hydroxyindole-3-carboxaldehyde) is a plant metabolite. 4-Hydroxy-1H-indole-3-carbaldehyde can be isolated from Capparis spinosa L. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the synthesis of fluorescent probe. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the study of inflammation-related diseases .

Cat. No.	Product Name	Chemical Structure

HY-79602S1

p-Toluenesulfonamide-15N
p-Toluenesulfonamide- ¹⁵N is the ¹⁵N-labeled p-Toluenesulfonamide (HY-79602). p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .

Cat. No.	Product Name		Classification

HY-D1506

Fl-DIBO		Labeling and Fluorescence Imaging
Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference . Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-131027

Janelia Fluor® 646, Azide JF646, Azide		Azide Labeling and Fluorescence Imaging
Janelia Fluor 646, Azide (JF646, Azide) is a red fluorogenic fluorescent dye containing a click chemistry group Azide. Janelia Fluor 646, Azide can be used for live-cell imaging experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-138659

Janelia Fluor® 646, Tetrazine JF646, Tetrazine		Labeling and Fluorescence Imaging Tetrazine
Janelia Fluor 646, Tetrazine (JF646, Tetrazine) a red fluorescent dye that contains a tetrazine group. JF646, Tetrazine can be used in cellular imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-131021

Janelia Fluor® 549, Azide 1 Publications Verification JF549, Azide		Azide Labeling and Fluorescence Imaging
Janelia Fluor? 549, Azide (JF549, Azide) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor? products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-131024

Janelia Fluor® 549, Tetrazine JF549, Tetrazine		Labeling and Fluorescence Imaging Tetrazine
Janelia Fluor® 549, Tetrazine (JF549, Tetrazine) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

Cat. No.	Product Name		Classification

HY-174497

eGFP mRNA		mRNA Reporter Genes
eGFP mRNA expresses green fluorescent protein derived from the jellyfish Aequorea victoria. eGFP is a commonly used direct-detection reporter gene in mammalian cell culture, which produces bright green fluorescence. This product is synthesized without modified nucleosides, with a Cap1 version cap analog at the 5' end and a 100nt PolyA tail at the 3' end. It can be used as a positive reference for IVT (in vitro transcription) or LNP delivery systems.

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