76-54-0
76-54-0
Chemical Structure
2',7'-Dichlorofluorescein
- CAS No.: 76-54-0
- Formula:C20H10Cl2O5
- Molecular Weight:401.20
IUPAC Name: 2',7'-dichloro-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
InChIKey: VFNKZQNIXUFLBC-UHFFFAOYSA-N
SMILES: O=C1OC2(C3=C(OC4=C2C=C(Cl)C(O)=C4)C=C(O)C(Cl)=C3)C5=C1C=CC=C5
Biological Activity: 2',7'-Dichlorofluorescein is an important fluorescent product in the detection of oxidative stress and can be used to measure reactive oxygen species (ROS) (Ex=503 nm and Em=523 nm)[1][2].
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2',7'-Dichlorofluorescein | 99.51% | 2',7'-Dichlorofluorescein is an important fluorescent product in the detection of oxidative stress and can be used to measure reactive oxygen species (ROS) (Ex=503 nm and Em=523 nm). | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.78
HY-D00772',7'-Difluorofluorescein -
Similarity Score 0.74
HY-D1151HKOH-1 -
Similarity Score 0.73
HY-D1244CO probe 1 -
Similarity Score 0.73
HY-1267932′,7′-Dichlorofluorescein diacetate -
Similarity Score 0.72
HY-D0251Fluorescein -
Similarity Score 0.70
HY-W2817133,6-Dichlorofluorescein -
Similarity Score 0.68
HY-130025HKOCl-3 -
Similarity Score 0.66
HY-D0254Gallein -
Similarity Score 0.66
HY-D0208Fluorescein sodium -
Explore the MedChemAI to find more analogs
References
- [1]. Reiniers MJ, et al. Preparation and Practical Applications of 2',7'-Dichlorodihydrofluorescein in Redox Assays. Anal Chem. 2017 Apr 4;89(7):3853-3857. [Content Brief]
- [2]. Xiuping Chen, et al. 2',7'-Dichlorodihydrofluorescein as a fluorescent probe for reactive oxygen species measurement: Forty years of application and controversy. Free Radic Res. 2010 Jun;44(6):587-604. [Content Brief]
