5 Results for "

fluorinated amino acid

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "fluorinated amino acid" in MCE Product Catalog:

Cat. No.: HY-W002291
CAS No.: 1132-68-9
Synonyms: 4-Fluoro-L-phenylalanine
p-Fluoro-L-phenylalanine (4-Fluoro-L-phenylalanine) is a fluorinated derivative of L-phenylalanine (HY-N0215). p-Fluoro-L-phenylalanine specifically binds to the L-leucine-specific receptor of Escherichia coli, with a Kd value of 0.26 μM .
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Cat. No.: HY-W010023
CAS No.: 869557-43-7
Synonyms: 3-Bromo-5-fluoro-2-pyridinamine
2-Amino-3-bromo-5-fluoropyridine (3-Bromo-5-fluoro-2-pyridinamine) is a drug intermediate that can be used for the synthesis fluorinated pyridines .
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Cat. No.: HY-65254
CAS No.: 1827-27-6
5-Amino-2-fluoropyridine is a fluorinated heterocyclic compound, which can be used for the synthesis of other active compounds .
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Cat. No.: HY-W040279
CAS No.: 94125-34-5
Research Areas:  

Others

Prosulfuron is a fluorinated sulfonylurea herbicide with a reported acute oral LD50 of 546 mg/kg in female rats. Prosulfuron acts by inhibiting acetolactate synthase (ALS) to block the biosynthesis of branched-chain amino acids (valine, leucine and isoleucine) in plants, thereby suppressing weed growth. Prosulfuron may disrupt the soil microbial community balance in alkaline soils with minimal chemical degradation. Prosulfuron has low toxicity to humans and mammals, and can be used for the research of broadleaf weed control in maize and sweet corn .
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Cat. No.: HY-P11615
Target:  

Bacterial

Research Areas:  

Infection

FuK is a WK2-analog antimicrobial peptide modified with fluorinated unnatural amino acids. FuK has an LD50 of 72.34 mg/kg in mice, shows no hemolytic activity, with high stability against trypsin, chymotrypsin, and saline environments. FuK exerts bactericidal effects by enhancing the permeability of bacterial outer membranes, inducing depolarization of cytoplasmic membranes, and disrupting membrane potential balance against bacterias such as Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, and MRSA. FuK exhibits synergistic antimicrobial activity with polymyxin B (HY-149179), vancomycin (HY-B0671), and ciprofloxacin (HY-B0356), and also inhibits Ciprofloxacin-induced bacterial drug resistance. FuK has in vivo safety, effectively reduces bacterial load and inflammatory cell infiltration in a mouse MRSA model, and promotes collagen fiber formation in skin wounds .
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