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Results for "

fluorinated amino acid

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

3

Biochemical Assay Reagents

1

Peptides

Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-W002291

    4-Fluoro-L-phenylalanine

    Drug Derivative Infection
    p-Fluoro-L-phenylalanine (4-Fluoro-L-phenylalanine) is a fluorinated derivative of L-phenylalanine (HY-N0215). p-Fluoro-L-phenylalanine specifically binds to the L-leucine-specific receptor of Escherichia coli, with a Kd value of 0.26 μM .
    p-Fluoro-L-phenylalanine
  • HY-W010023

    3-Bromo-5-fluoro-2-pyridinamine

    Drug Intermediate Others
    2-Amino-3-bromo-5-fluoropyridine (3-Bromo-5-fluoro-2-pyridinamine) is a drug intermediate that can be used for the synthesis fluorinated pyridines .
    2-Amino-3-bromo-5-fluoropyridine
  • HY-65254

    Biochemical Assay Reagents Drug Intermediate Others
    5-Amino-2-fluoropyridine is a fluorinated heterocyclic compound, which can be used for the synthesis of other active compounds .
    5-Amino-2-fluoropyridine
  • HY-W040279

    Herbicide Acetolactate Synthase (ALS) Others
    Prosulfuron is a fluorinated sulfonylurea herbicide with a reported acute oral LD50 of 546 mg/kg in female rats. Prosulfuron acts by inhibiting acetolactate synthase (ALS) to block the biosynthesis of branched-chain amino acids (valine, leucine and isoleucine) in plants, thereby suppressing weed growth. Prosulfuron may disrupt the soil microbial community balance in alkaline soils with minimal chemical degradation. Prosulfuron has low toxicity to humans and mammals, and can be used for the research of broadleaf weed control in maize and sweet corn .
    Prosulfuron
  • HY-P11615

    Bacterial Infection
    FuK is a WK2-analog antimicrobial peptide modified with fluorinated unnatural amino acids. FuK has an LD50 of 72.34 mg/kg in mice, shows no hemolytic activity, with high stability against trypsin, chymotrypsin, and saline environments. FuK exerts bactericidal effects by enhancing the permeability of bacterial outer membranes, inducing depolarization of cytoplasmic membranes, and disrupting membrane potential balance against bacterias such as Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, and MRSA. FuK exhibits synergistic antimicrobial activity with polymyxin B (HY-149179), vancomycin (HY-B0671), and ciprofloxacin (HY-B0356), and also inhibits Ciprofloxacin-induced bacterial drug resistance. FuK has in vivo safety, effectively reduces bacterial load and inflammatory cell infiltration in a mouse MRSA model, and promotes collagen fiber formation in skin wounds .
    FuK

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