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gallic

" in MedChemExpress (MCE) Product Catalog:

30

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18

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2

Isotope-Labeled Compounds

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0523
    Gallic acid
    Maximum Cited Publications
    16 Publications Verification

    3,4,5-Trihydroxybenzoic acid

    COX Reactive Oxygen Species (ROS) Apoptosis Ferroptosis Endogenous Metabolite Metabolic Disease Cancer
    Gallic acid (3,4,5-Trihydroxybenzoic acid) is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) . Gallic acid has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities .
    Gallic acid
  • HY-N0527
    Pentagalloylglucose
    10+ Cited Publications

    Penta-O-galloyl-β-D-glucose; 1,2,3,4,6-Pentagalloyl glucose

    JAK Keap1-Nrf2 Apoptosis β-catenin Reactive Oxygen Species (ROS) E1/E2/E3 Enzyme Neurological Disease Inflammation/Immunology Cancer
    Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) is an orally active gallic tannin compound and an inducer of apoptosis and autophagy. Pentagalloglucose induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway. Pentagalloylglucose inhibits UBE2T-mediated p53 ubiquitination, upregulates p53, downregulates RRM1/RRM2 in pancreatic cancer organoids. Pentagalloglucose has antioxidant, anti mutagenic, anti-inflammatory, anticonvulsant, cardioprotective, anti allergic, cholesterol lowering, and anti-tumor activities .
    Pentagalloylglucose
  • HY-N0523A
    Gallic acid hydrate
    15+ Cited Publications

    3,4,5-Trihydroxybenzoic acid hydrate

    COX Reactive Oxygen Species (ROS) Apoptosis Ferroptosis Endogenous Metabolite Inflammation/Immunology Cancer
    Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) . Gallic acid hydrate has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities .
    Gallic acid hydrate
  • HY-P2877

    Endogenous Metabolite Others
    Tannase is a tannin acyl hydrolase. Tannase catalyzes the hydrolysis of ester bonds in gallotannins, complex tannins and gallic acid esters to release gallic acid. Tannase plays a role in industrial production, including the manufacture of instant tea, beer, fruit juice, some wines, and the production of gallic acid .
    Tannase
  • HY-W004486
    Gallic aldehyde
    1 Publications Verification

    HSV MMP ERK p38 MAPK JNK Infection
    Gallic aldehyde (3,4,5-Trihydroxybenzaldehyde) is a phenolic aldehyde. Gallic aldehyde can be isolated from Geum japonicum. Gallic aldehyde inhibits the gelatinolytic activity and expression of MMP-9. Gallic aldehyde also inhibits ERK1/2, p38, and JNK. Gallic aldehyde has potent anti-HSV-1 and antioxidant activities. Gallic aldehyde also exhibits antibacterial activity against Oenococcus oeni VF .
    Gallic aldehyde
  • HY-N0523R

    3,4,5-Trihydroxybenzoic acid (Standard)

    Reference Standards COX Reactive Oxygen Species (ROS) Apoptosis Ferroptosis Endogenous Metabolite Metabolic Disease Cancer
    Gallic acid (Standard) is the analytical standard of Gallic acid. This product is intended for research and analytical applications. Gallic acid (3,4,5-Trihydroxybenzoic acid) is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) . Gallic acid has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities .
    Gallic acid (Standard)
  • HY-N0523S

    3,4,5-Trihydroxybenzoic acid-d2

    Apoptosis COX Ferroptosis Endogenous Metabolite Reactive Oxygen Species (ROS) Cancer
    Gallic acid-d2 is the deuterium labeled Gallic acid . Gallic acid (3,4,5-Trihydroxybenzoic acid) is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) . Gallic acid has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities .
    Gallic acid-d2
  • HY-N3287

    Bacterial Fungal Reactive Oxygen Species (ROS) Infection
    Methyl 3-hydroxy-4,5-dimethoxybenzoate is a gallic acid derivant that can be isolated from myricaria Laxiflora. Methyl 3-hydroxy-4,5-dimethoxybenzoate shows obvious antimicrobial activities. Methyl 3-hydroxy-4,5-dimethoxybenzoate shows fairly active for oxidation resistance in the presence of H2O2 .
    Methyl 3-hydroxy-4,5-dimethoxybenzoate
  • HY-N1652

    3,3′,4-Tri-O-methylellagic acid

    Others Others
    2,3,8-Tri-O-methylellagic acid is a terpenoids that can be isolated from the stem bark of Neoboutonia macrocalyx. 2,3,8-Tri-O-methylellagic acid is found to be 50 times more active than the parent ellagic acid .
    2,3,8-Tri-O-methylellagic acid
  • HY-135652

    Hexyl 3,4,5-trihydroxybenzoate

    Bacterial Parasite Infection
    Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) shows antibacterial activity and inhibits the production of rhamnolipid and pyocyanin by inhibiting RhlR . Hexyl gallate, a alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum, with IC50 of 0.11 mM .
    Hexyl gallate
  • HY-W004486R

    Reference Standards HSV MMP ERK p38 MAPK JNK Infection
    Gallic aldehyde (Standard) is an analytical standard of Gallic aldehyde (HY-W004486). This product is intended for research and analytical applications. Gallic aldehyde (3,4,5-Trihydroxybenzaldehyde) is a phenolic aldehyde. Gallic aldehyde can be isolated from Geum japonicum. Gallic aldehyde inhibits the gelatinolytic activity and expression of MMP-9. Gallic aldehyde also inhibits ERK1/2, p38, and JNK. Gallic aldehyde has potent anti-HSV-1 and antioxidant activities. Gallic aldehyde also exhibits antibacterial activity against Oenococcus oeni VF .
    Gallic aldehyde (Standard)
  • HY-N6877

    Others Cancer
    Purpurogallin carboxylic acid, isolated from Macleaya microcarpa (Maxim.) Fedde, is an oxidation product of gallic acid in fermented tea. Purpurogallin carboxylic acid has anti-cancer activity .
    Purpurogallin carboxylic acid
  • HY-N2044

    Others Others
    Methyl 3,4,5-trimethoxybenzoate can be synthesized from Gallic acid. Methyl 3,4,5-trimethoxybenzoate is mainly used in the production of Trimethoprim (TMP), Sulfa synergistic intermediates, and many other agents.
    Methyl 3,4,5-trimethoxybenzoate
  • HY-N0523AR

    3,4,5-Trihydroxybenzoic acid hydrate (Standard)

    Reference Standards COX Reactive Oxygen Species (ROS) Apoptosis Ferroptosis Endogenous Metabolite Inflammation/Immunology Cancer
    Gallic acid (hydrate) (Standard) is the analytical standard of Gallic acid (hydrate). This product is intended for research and analytical applications. Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) . Gallic acid hydrate has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities .
    Gallic acid hydrate (Standard)
  • HY-N0527R

    Penta-O-galloyl-β-D-glucose (Standard); 1,2,3,4,6-Pentagalloyl glucose (Standard)

    Reference Standards JAK Keap1-Nrf2 Apoptosis β-catenin Reactive Oxygen Species (ROS) Neurological Disease Inflammation/Immunology Cancer
    Pentagalloylglucose (Standard) is the analytical standard of Pentagalloylglucose. This product is intended for research and analytical applications. Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) is an orally active gallic tannin compound and an inducer of apoptosis and autophagy. Pentagalloglucose induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway. Pentagalloylglucose inhibits UBE2T-mediated p53 ubiquitination, upregulates p53, downregulates RRM1/RRM2 in pancreatic cancer organoids. Pentagalloglucose has antioxidant, anti mutagenic, anti-inflammatory, anticonvulsant, cardioprotective, anti allergic, cholesterol lowering, and anti-tumor activities .
    Pentagalloylglucose (Standard)
  • HY-P1934AR

    Reference Standards Fungal Bacterial IFNAR Reactive Oxygen Species (ROS) Infection Inflammation/Immunology Cancer
    Gallic acid (hydrate) (Standard) is the analytical standard of Gallic acid (hydrate). This product is intended for research and analytical applications. Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC50 of 24 µM in the DPPH assay .
    Cyclo(L-Phe-L-Pro) (Standard)
  • HY-147666

    α-synuclein Neurological Disease
    α-Synuclein inhibitor 4 (compound 3gh) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 0.98 μM and inhibition ratio at 30 μM of 91.2% .
    α-Synuclein inhibitor 4
  • HY-147667

    α-synuclein Neurological Disease
    α-Synuclein inhibitor 5 (compound 4aa) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 1.22 μM and inhibition ratio at 30 μM of 94.3% .
    α-Synuclein inhibitor 5
  • HY-147669

    α-synuclein Neurological Disease
    α-Synuclein inhibitor 7 (compound 3gf) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 1.95 μM and inhibition ratio at 30 μM of 85.8% .
    α-Synuclein inhibitor 7
  • HY-147668

    α-synuclein Neurological Disease
    α-Synuclein inhibitor 6 (compound 3ge) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 1.70 μM and inhibition ratio at 30 μM of 94.4% .
    α-Synuclein inhibitor 6
  • HY-N17526

    Others Others
    Gallic acid 3-O-(6′-O-galloyl)-β-D-glucopyranoside is a polyphenol that can be found in the fruits of Camellia japonica L. .
    Gallic acid 3-O-(6′-O-galloyl)-β-D-glucopyranoside
  • HY-N18064

    Others Others
    Mudanoside B is a gallic acid glycoside found in the dried root cortex of Paeonia suffruticosa .
    Mudanoside B
  • HY-185044

    Drug Intermediate Others
    Galloyl-coenzyme A thioester is a CoA-thioester of Gallic acid (HY-N05230) that can be found in plants as an intermediate in gallotannin biosynthesis.Galloyl-coenzyme A thioester possesses spectral properties that support photometric assay use in enzymatic studies .
    Galloyl-coenzyme A thioester
  • HY-P2877A

    Biochemical Assay Reagents Metabolic Disease
    Tannase, Aspergillus oryzae (EC 3.1.1.20) catalyzes the hydrolysis of tannic acid to produce gallic acid and glucose.
    Tannase, Aspergillus oryzae
  • HY-N19081

    Bacterial Infection Inflammation/Immunology
    Terminalia belerica extract is rich in various bioactive compounds, such as tannins, gallic acid, ellagic acid, chebulic acid, and various sugars including glucose and fructose. Terminalia belerica extract possesses antioxidant, antibacterial, anti-inflammatory, and hepatoprotective effects.
    Terminalia belerica extract
  • HY-N18727

    Bacterial Infection Inflammation/Immunology
    Emblic extract is derived from the fruit of a small tree native to India. Its active ingredients include vitamin C, tannins, flavonoids, polyphenols, and gallic acid, which give it powerful antioxidant, anti-inflammatory, and antibacterial properties.
    Emblic extract
  • HY-N18782

    Others Inflammation/Immunology
    Quercus infectoria extract is an extract from the fruit of the oak tree (Quercus infectoria) known for its powerful astringent, anti-inflammatory, and antioxidant properties. The active ingredients in Quercus infectoria extract include tannins (such as ellagic acid and gallic acid), flavonoids, and catechins.
    Quercus infectoria extract
  • HY-N2044S

    Isotope-Labeled Compounds Others
    Methyl 3,4,5-trimethoxybenzoate-d9 is the deuterium labeled Methyl 3,4,5-trimethoxybenzoate . Methyl 3,4,5-trimethoxybenzoate can be synthesized from Gallic acid. Methyl 3,4,5-trimethoxybenzoate is mainly used in the production of Trimethoprim (TMP), Sulfa synergistic intermediates, and many other agents .
    Methyl 3,4,5-trimethoxybenzoate-d9
  • HY-N17855

    Glycosidase Reactive Oxygen Species (ROS) Metabolic Disease
    Guavinoside B is an orally active α-glucosidase inhibitor with an IC50 of 0.21 mM. Guavinoside B upregulates the expressions of Nrf2, GCLC and NQO1 induced by Acetaminophen (HY-66005), downregulates the expression of p-JNK, and reduces intracellular ROS levels. Guavinoside B decreases serum TNF-α levels induced by Acetaminophen, alleviates hepatocellular infiltration and necrosis, and improves liver-related biochemical parameters. Guavinoside B is applicable to the research of diabetes and Acetaminophen-induced liver injury .
    Guavinoside B
  • HY-N18656

    Bacterial Infection
    Terminalia chebula extract, derived from the fruit of the Terminalia chebula tree. Rich in bioactive compounds such as tannins, flavonoids, phenols, and organic acids like gallic acid and ellagic acid, this extract demonstrates a wide range of pharmacological activities. It acts as a natural laxative, supports digestive health, and exhibits potent antioxidant, anti-inflammatory, and antibacterial properties, effectively targeting various pathogenic bacteria, including Helicobacter pylori, Staphylococcus aureus, and Escherichia coli. Terminalia Chebula Extract also shows significant hepatoprotective effects, shielding the liver from damage through antioxidant and anti-inflammatory mechanisms. It has nephroprotective properties, alleviating renal dysfunction and enhancing kidney health by modulating inflammatory pathways. Additionally, the extract demonstrates neuroprotective activity, reducing neuronal damage and improving memory function. It has potential anti-diabetic effects, enhancing glucose uptake and reducing oxidative stress.
    Terminalia chebula extract

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