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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
hCE1
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "hCE1" in MCE Product Catalog:
1
Tefinostat (CHR-2845) is a monocyte/macrophage targeted histone deacetylase (HDAC) inhibitor. Tefinostat can be cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Tefinostat can be used for the research of leukaemias [1].
Cat. No.: HY-N1377
CAS No.: 10176-66-6
Synonyms: Lysionotin
Cat. No.: HY-N10686
CAS No.: 61077-78-9
Target:
Target:
Research Areas:
1-Methylisatin is a potent and selective CE (carboxylesterases) inhibitor, with Kis of 38.2 and 5.38 μM for hiCE and hCE1, respectively. 1-Methylisatin interacts with Hb (human adult hemoglobin) by hydrophobic binding and electrostatic attraction. 1-Methylisatin can be used in the study of regulation of agent metabolism in vivo [1] .
Target:
Research Areas:
Dibromsalicil (Compound 31) is a carboxylesterase (CES) inhibitor with activity of 72.7 nM against hiCE (human intestinal carboxylesterase) and 53.5 nM against rCE (rabbit liver carboxylesterase). Dibromsalicil has almost no activity against hCE1 (human liver carboxylesterase) and cholinesterase [1].
Target:
Research Areas:
Pancreatic lipase/Carboxylesterase 1-IN-1 (Compound 39) is a potent dual inhibitor of pancreatic lipase (PL) and human carboxylesterase 1A (hCES1A) with IC50 values of 2.13 µM and 0.055 µM against PL and hCES1A [1].
Cat. No.: HY-N1377R
CAS No.: 10176-66-6
Synonyms: Lysionotin (Standard)
Cat. No.: HY-106409R
CAS No.: 914382-60-8
Synonyms: CHR-2845 (Standard)
Target:
Research Areas:
Tefinostat (Standard) is the analytical standard of Tefinostat (HY-106409). This product is intended for research and analytical applications. Tefinostat (CHR-2845) is a monocyte/macrophage targeted histone deacetylase (HDAC) inhibitor. Tefinostat can be cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Tefinostat can be used for the research of leukaemias [1].
Cat. No.: HY-RS12099
Target:
Research Areas:
RNGTT Human Pre-designed siRNA Set A contains three designed siRNAs for RNGTT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02543
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Research Areas:
CES1 Human Pre-designed siRNA Set A contains three designed siRNAs for CES1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P7730
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CES1; Cocaine Carboxylesterase; Carboxylesterase 1; Retinyl Ester Hydrolase; HMSE; Serine Esterase 1; CES2; CES1A1; SES1; CES1A2; CEH; Egasyn; HMSE1; hCE-1; Carboxylesterase 1 (Monocyte/Macrophage Serine Esterase 1); ACAT; Human Monocyte/Macrophage Serine
Species:
Human
Source:
HEK293
Cat. No.: HY-P703886
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CES1; Cocaine Carboxylesterase; Carboxylesterase 1; Retinyl Ester Hydrolase; HMSE; Serine Esterase 1; CES2; CES1A1; SES1; CES1A2; CEH; Egasyn; HMSE1; hCE-1; Carboxylesterase 1 (Monocyte/Macrophage Serine Esterase 1); ACAT; Human Monocyte/Macrophage Serine
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
