Search Result
Results for "
hydrazide groups
" in MedChemExpress (MCE) Product Catalog:
6
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-W440823A
-
|
DSPE-PEG1000-NH2 ammonium
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-Amine (DSPE-PEG1000-NH2) ammonium is a 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol conjugate with a terminal amino group. DSPE-PEG1000-Amine ammonium can functionalize the surface of PLGA-lecithin-PEG core-shell nanoparticles to introduce positive surface charges. The amino group of DSPE-PEG1000-Amine ammonium can be converted into an aromatic aldehyde to react with the acetone-protected aromatic hydrazide on the surface of bovine carbonic anhydrase (BCA) molecules .
|
-
-
- HY-147168
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biocytin hydrazide is a long-chain biotin-containing hydrazide, serving as a biotin-derived active coupling reagent, selective labeling agent and biotinylating reagent. Biocytin hydrazide targets aldehyde, carboxyl, amino and guanidino groups to biotinylate glycoconjugates, K99 lectin, peptides and proteins through its hydrazide moiety, and achieves nonradioactive detection of sialic acid- and galactose-containing glycoconjugates via the avidin–biotin system .
|
-
-
- HY-140814
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
-
- HY-155907
-
|
DSPE-PEG5000-NH2 ammonium
|
Liposome
|
Others
|
|
DSPE-PEG5000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG5000-Amine ammonium amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
|
-
-
- HY-133427
-
|
|
ADC Linker
|
Cancer
|
|
Propargyl-PEG4-hydrazide is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-hydrazide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
-
- HY-140815
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG8-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
-
- HY-D2502
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 hydrazide is a Cy7 (HY-D0825) dye derivative with hydrazine functionality. The hydrazide group of Cy7 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
|
-
-
- HY-D1324
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5.5 hydrazide, an analog of Cyanine5.5 fluorophore, is a near-infrared (NIR) fluorescent dye. Cyanine5.5 hydrazide is used for labeling of biomolecules through the condensation between the hydrazide groups and the carbonyl groups. (λex=684 nm, λem=710 nm) .
|
-
-
- HY-W800657
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Azido-PEG1-hydrazide hydrochloride is a bifunctional PEG linker containing an azide group and a hydrazide group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Hydrazine moiety reacts with an aldehyde to form semi-permanent hydrazone bonds.
|
-
-
- HY-132263
-
|
|
Fluorescent Dye
|
Others
|
|
FAM hydrazide, 5-isomer is a Fluorescein dye linker containing a hydrazide group. Fluorescein is a universal dye. Hydrazide moieties react with aldehydes to form semi-permanent hydrazone bonds.
|
-
-
- HY-D2388
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy5.5-hydrazide is a Cy5.5 (HY-D0924) dye derivative with hydrazine functionality. The hydrazide group of Sulfo Cy5.5-hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
|
-
-
- HY-133438
-
|
|
PROTAC Linkers
|
Cancer
|
|
BCN-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
-
- HY-133321
-
|
|
PROTAC Linkers
|
Cancer
|
|
N3-PEG24-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG24-Hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
-
- HY-130886
-
|
Azide-PEG12-hydrazide
|
PROTAC Linkers
|
Cancer
|
|
N3-PEG12-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG12-Hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
-
- HY-133320
-
|
|
PROTAC Linkers
|
Cancer
|
|
N3-PEG16-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG16-Hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
-
- HY-140818
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Azido-PEG8-hydrazide-Boc is a PEG linker which contains an azide moiety and a Boc-protected hydrazide. Azido-PEG8-hydrazide-Boc is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups.
|
-
-
- HY-140817
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-hydrazide-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
-
- HY-140816
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG2-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG2-hydrazide-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
-
- HY-D2151
-
|
|
Fluorescent Dye
|
Others
|
|
AF 430 hydrazide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 hydrazide can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) via the Azide group and molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. To achieve specific coupling of dye labels and biomolecules .
|
-
-
- HY-W591969
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Benzyl (6-oxohexyl)carbamate is a linker containing an aldehyde group and a benzyl (Cbz) protecting group. The aldehyde can react with hydrazine or hydrazide to form a hydrolytic acyl hydrozone linkage. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
|
-
-
- HY-D1861
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3 hydrazide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative with hydrazine functionality. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The hydrazide group of Sulfo-Cy3 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds. Therefore, Cy3 azide plus can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
-
- HY-W1048872C
-
|
4-Arm-PEG20000-HZ
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG20000-Hydrazide (4-Arm-PEG20000-HZ) is a four-arm PEG derivative. The core structure of 4-Arm-PEG20000-Hydrazide consists of four PEG chains, each modified at the end with a hydrazide group. 4-Arm-PEG20000-Hydrazide can be used for bioconjugation and drug delivery.
|
-
-
- HY-W1048872A
-
|
4-Arm-PEG5000-HZ
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG5000-Hydrazide (4-Arm-PEG5000-HZ) is a four-arm PEG derivative. The core structure of 4-Arm-PEG5000-Hydrazide consists of four PEG chains, each modified at the end with a hydrazide group. 4-Arm-PEG5000-Hydrazide can be used for bioconjugation and drug delivery.
|
-
-
- HY-W1048872E
-
|
4-Arm-PEG2000-HZ
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG2000-Hydrazide (4-Arm-PEG2000-HZ) is a four-arm PEG derivative. The core structure of 4-Arm-PEG2000-Hydrazide consists of four PEG chains, each modified at the end with a hydrazide group. 4-Arm-PEG2000-Hydrazide can be used for bioconjugation and drug delivery.
|
-
-
- HY-W1048872B
-
|
4-Arm-PEG10000-HZ
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG10000-Hydrazide (4-Arm-PEG10000-HZ) is a four-arm PEG derivative. The core structure of 4-Arm-PEG10000-Hydrazide consists of four PEG chains, each modified at the end with a hydrazide group. 4-Arm-PEG10000-Hydrazide can be used for bioconjugation and drug delivery.
|
-
-
- HY-D2388A
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy5.5-hydrazide sodium is a Cy5.5 (HY-D0924) dye derivative with hydrazine functionality. The hydrazide group of Sulfo Cy5.5-hydrazide sodium can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
|
-
-
- HY-W840196
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Hex-5-ynehydrazide is a bifunctional linker reagent with a terminal hydrazide group and a propargyl group. The hydrazide group can react with an aldehyde to form a semi-permanent hydrozone bond. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry.
|
-
-
- HY-W190720
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Fmoc-NH-PEG4-HZ-BOC is a PEG reagent containing an Fmoc-protected amine and a Boc-protected hydrazide. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc can be deprotected under mild acidic conditions to form a reactive hydrazide, which can then be coupled with various carbonyl groups.
|
-
-
- HY-W143230
-
|
4-Benzyloxybutanal
|
Biochemical Assay Reagents
|
Others
|
|
4-(Benzyloxy)butanal (4-Benzyloxybutanal) is a linker with an acid labile, benzyl protecting group and a reactive primary aldehyde. The primary aldehyde can react with hydrazide and aminooxy groups which are commonly used in biomolecular probes for labeling and crosslinking carbonyls (oxidized carbohydrates).
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D2502
-
|
|
Fluorescent Dye
|
|
Cy7 hydrazide is a Cy7 (HY-D0825) dye derivative with hydrazine functionality. The hydrazide group of Cy7 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
|
-
- HY-D1324
-
|
|
Fluorescent Dye
|
|
Cyanine5.5 hydrazide, an analog of Cyanine5.5 fluorophore, is a near-infrared (NIR) fluorescent dye. Cyanine5.5 hydrazide is used for labeling of biomolecules through the condensation between the hydrazide groups and the carbonyl groups. (λex=684 nm, λem=710 nm) .
|
-
- HY-132263
-
|
|
Fluorescent Dye
|
|
FAM hydrazide, 5-isomer is a Fluorescein dye linker containing a hydrazide group. Fluorescein is a universal dye. Hydrazide moieties react with aldehydes to form semi-permanent hydrazone bonds.
|
-
- HY-D2388
-
|
|
Fluorescent Dye
|
|
Sulfo Cy5.5-hydrazide is a Cy5.5 (HY-D0924) dye derivative with hydrazine functionality. The hydrazide group of Sulfo Cy5.5-hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
|
-
- HY-D2151
-
|
|
Fluorescent Dye
|
|
AF 430 hydrazide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 hydrazide can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) via the Azide group and molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-D1861
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy3 hydrazide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative with hydrazine functionality. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The hydrazide group of Sulfo-Cy3 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds. Therefore, Cy3 azide plus can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D2388A
-
|
|
Fluorescent Dye
|
|
Sulfo Cy5.5-hydrazide sodium is a Cy5.5 (HY-D0924) dye derivative with hydrazine functionality. The hydrazide group of Sulfo Cy5.5-hydrazide sodium can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
|
-
- HY-W840196
-
|
|
Fluorescent Dye
|
|
Hex-5-ynehydrazide is a bifunctional linker reagent with a terminal hydrazide group and a propargyl group. The hydrazide group can react with an aldehyde to form a semi-permanent hydrozone bond. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry.
|
| Cat. No. |
Product Name |
Type |
-
- HY-W440823A
-
|
DSPE-PEG1000-NH2 ammonium
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-Amine (DSPE-PEG1000-NH2) ammonium is a 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol conjugate with a terminal amino group. DSPE-PEG1000-Amine ammonium can functionalize the surface of PLGA-lecithin-PEG core-shell nanoparticles to introduce positive surface charges. The amino group of DSPE-PEG1000-Amine ammonium can be converted into an aromatic aldehyde to react with the acetone-protected aromatic hydrazide on the surface of bovine carbonic anhydrase (BCA) molecules .
|
-
- HY-155907
-
|
DSPE-PEG5000-NH2 ammonium
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG5000-Amine ammonium amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
|
-
- HY-W1048872C
-
|
4-Arm-PEG20000-HZ
|
Biochemical Assay Reagents
|
|
4-Arm-PEG20000-Hydrazide (4-Arm-PEG20000-HZ) is a four-arm PEG derivative. The core structure of 4-Arm-PEG20000-Hydrazide consists of four PEG chains, each modified at the end with a hydrazide group. 4-Arm-PEG20000-Hydrazide can be used for bioconjugation and drug delivery.
|
-
- HY-W1048872A
-
|
4-Arm-PEG5000-HZ
|
Biochemical Assay Reagents
|
|
4-Arm-PEG5000-Hydrazide (4-Arm-PEG5000-HZ) is a four-arm PEG derivative. The core structure of 4-Arm-PEG5000-Hydrazide consists of four PEG chains, each modified at the end with a hydrazide group. 4-Arm-PEG5000-Hydrazide can be used for bioconjugation and drug delivery.
|
-
- HY-W1048872E
-
|
4-Arm-PEG2000-HZ
|
Biochemical Assay Reagents
|
|
4-Arm-PEG2000-Hydrazide (4-Arm-PEG2000-HZ) is a four-arm PEG derivative. The core structure of 4-Arm-PEG2000-Hydrazide consists of four PEG chains, each modified at the end with a hydrazide group. 4-Arm-PEG2000-Hydrazide can be used for bioconjugation and drug delivery.
|
-
- HY-W1048872B
-
|
4-Arm-PEG10000-HZ
|
Biochemical Assay Reagents
|
|
4-Arm-PEG10000-Hydrazide (4-Arm-PEG10000-HZ) is a four-arm PEG derivative. The core structure of 4-Arm-PEG10000-Hydrazide consists of four PEG chains, each modified at the end with a hydrazide group. 4-Arm-PEG10000-Hydrazide can be used for bioconjugation and drug delivery.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-140814
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133427
-
|
|
|
Alkynes
ADC Synthesis
|
|
Propargyl-PEG4-hydrazide is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-hydrazide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140815
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG8-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W800657
-
|
|
|
Azide
|
|
Azido-PEG1-hydrazide hydrochloride is a bifunctional PEG linker containing an azide group and a hydrazide group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Hydrazine moiety reacts with an aldehyde to form semi-permanent hydrazone bonds.
|
-
- HY-133321
-
|
|
|
Azide
PROTAC Synthesis
|
|
N3-PEG24-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG24-Hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130886
-
|
Azide-PEG12-hydrazide
|
|
PROTAC Synthesis
Azide
|
|
N3-PEG12-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG12-Hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133320
-
|
|
|
Azide
PROTAC Synthesis
|
|
N3-PEG16-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG16-Hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140818
-
|
|
|
Azide
|
|
Azido-PEG8-hydrazide-Boc is a PEG linker which contains an azide moiety and a Boc-protected hydrazide. Azido-PEG8-hydrazide-Boc is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups.
|
-
- HY-140817
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG4-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-hydrazide-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140816
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG2-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG2-hydrazide-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W840196
-
|
|
|
Alkynes
|
|
Hex-5-ynehydrazide is a bifunctional linker reagent with a terminal hydrazide group and a propargyl group. The hydrazide group can react with an aldehyde to form a semi-permanent hydrozone bond. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-W440823A
-
|
DSPE-PEG1000-NH2 ammonium
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-Amine (DSPE-PEG1000-NH2) ammonium is a 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol conjugate with a terminal amino group. DSPE-PEG1000-Amine ammonium can functionalize the surface of PLGA-lecithin-PEG core-shell nanoparticles to introduce positive surface charges. The amino group of DSPE-PEG1000-Amine ammonium can be converted into an aromatic aldehyde to react with the acetone-protected aromatic hydrazide on the surface of bovine carbonic anhydrase (BCA) molecules .
|
-
- HY-155907
-
|
DSPE-PEG5000-NH2 ammonium
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG5000-Amine ammonium amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
|
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
