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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
lipopolysaccharide-induced macrophages
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "lipopolysaccharide-induced macrophages" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: Hexadecadrol(Standard); Prednisolone F (Standard)
Target:
Reference Standards Exosomes Glucocorticoid Receptor SARS-CoV Autophagy Complement System Mitophagy Bacterial Antibiotic ADC Payloads
Research Areas:
Dexamethasone (Standard) is the analytical standard of Dexamethasone. This product is intended for research and analytical applications. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.
1
1 Cited Publications
Category:
Bletilla striata (Thunb. ex Murray) Rchb. f. Orchidaceae Ketones, Aldehydes, Acids Other Diseases Plants Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-N9447
CAS No.: 79595-97-4
Category:
Target:
Research Areas:
15-LOX-1 inhibitor 1 is a potent inhibitor of 15-LOX-1 (15-lipoxygenase-1) with an IC50 value of 0.19 μM. 15-LOX-1 inhibitor 1 protects macrophages from lipopolysaccharide-induced cytotoxicity. 15-LOX-1 inhibitor 1 inhibits NO formation and lipid peroxidation .
Synonyms: Hexadecadrol-d5; Prednisolone F-d5
Cat. No.: HY-14648S5
Purity: 98.02%
Synonyms: Hexadecadrol-d3-1; Prednisolone F-d3-1
Cat. No.: HY-N8160
CAS No.: 38230-32-9
Cat. No.: HY-14648S2
CAS No.: 2305607-27-4
Synonyms: Hexadecadrol-d4; Prednisolone F-d4
Cat. No.: HY-14648S1
Synonyms: Hexadecadrol-d5-1; Prednisolone F-d5-1
Cat. No.: HY-121892
CAS No.: 1646795-60-9
Cat. No.: HY-187062
CAS No.: 209969-75-5
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Cat. No.: HY-184337
CAS No.: 143111-84-6
Target:
Research Areas:
Dihydroparadol is a iNOS inhibitor with an IC50 of 7.24 μM, and it is found in ginger. Dihydroparadol partially inhibits the catalytic activity of iNOS, blocks the nuclear translocation of NF-κB p65, reduces NF-κB activity, and attenuates lipopolysaccharide-induced degradation of IκB-α, thereby inhibiting NF-κB-mediated iNOS gene expression and protein production. Dihydroparadol inhibits lipopolysaccharide-induced nitric oxide production in macrophages and exhibits anti-inflammatory activity. Dihydroparadol increases ABCA1 protein abundance by elevating mRNA levels and reducing proteasomal degradation, and also increases ABCG1 protein abundance by enhancing protein stability. Dihydroparadol promotes cholesterol efflux from cholesterol-loaded macrophages via apolipoprotein A1-mediated and plasma-mediated pathways. Dihydroparadol inhibits PDGF-induced vascular smooth muscle cell proliferation, shows no cytotoxicity to vascular smooth muscle cells within the tested concentration range, and does not interfere with endothelial cell proliferation. Dihydroparadol can be used in the research of inflammatory diseases, atherosclerosis and cardiovascular diseases .
Cat. No.: HY-N19813
CAS No.: 1807855-01-1
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Cat. No.: HY-182282
Target:
Research Areas:
PI3K/AKT-IN-6 is an orally effective PI3K/AKT signaling pathway inhibitor and anti-inflammatory agent. PI3K/AKT-IN-6 inhibits the production of pro-inflammatory cytokines TNF-α and IL-6, and downregulates the expression of inflammatory mediators COX-2 and iNOS. PI3K/AKT-IN-6 improves related symptoms in colitis mice. PI3K/AKT-IN-6 can be used for the research of inflammatory diseases such as colitis .
Cat. No.: HY-N21744
CAS No.: 54781-72-5
Target:
Cat. No.: HY-N7423A
CAS No.: 97966-29-5
Synonyms: (E)-Isoferulic acid methyl ester
Cat. No.: HY-N21746
CAS No.: 798558-82-4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
