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Cat. No.: HY-N21744

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Rhodomollein XIII

Rhodomollein XIII is a grayanane diterpenoid found in Rhododendron molle and is the 6-O-acetyl derivative of Grayanotoxin III.

For research use only. We do not sell to patients.

CAS No.: 54781-72-5
Formula: C₂₂H₃₆O₇
Molecular Weight:412.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Rhodomollein XIII Chemical Structure

CAS No.: 54781-72-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Rhodomollein XIII is a grayanane diterpenoid found in Rhododendron molle and is the 6-O-acetyl derivative of Grayanotoxin III^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC50	>40 μM	Inhibition of nitric oxide production in lipopolysaccharide-stimulated RAW264.7 mouse macrophages. Inhibition of nitric oxide production in lipopolysaccharide-stimulated RAW264.7 mouse macrophages.	29272126

In Vitro

Rhodomollein XIII (compound 27) shows no significant inhibitory effect on nitric oxide production in LPS-induced RAW264.7 mouse macrophages, with an IC₅₀ greater than 40 μM^[1].
Rhodomollein XIII is initially identified as the 6-O-acetyl derivative of Grayanotoxin III^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 54781-72-5
Molecular Weight 412.52
Formula C₂₂H₃₆O₇
SMILES

O[C@H]1[C@@]23[C@](CC[C@@]1([H])[C@](O)(C3)C)([H])[C@@](O)([C@@]4([H])[C@]([C@@H](C2)OC(C)=O)(C(C)([C@H](C4)O)C)O)C
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhou J, et al. Anti-inflammatory Grayanane Diterpenoids from the Leaves of Rhododendron molle. Journal of natural products. 2018 Jan 26;81(1):151-161. [Content Brief]

[2]. Zheng G, et al. Structurally diverse analgesic diterpenoids from the flowers of Rhododendron molle. Fitoterapia. 2024 Jan;172:105770.

[3]. Zou HY, et al. Tandem solid-phase extraction followed by HPLC-ESI/QTOF/MS/MS for rapid screening and structural identification of trace diterpenoids in flowers of Rhododendron molle. Phytochemical analysis : PCA. 2014;25(3):255-65.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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