45 Results for "

mesothelin

" in MedChemExpress (MCE) Product Catalog:
Products (45)

45 Results for "mesothelin" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99006
CAS No.: 931402-35-6
Synonyms: MORab-009

Target:  

Mesothelin

Research Areas:  

Cancer

Amatuximab (MORab-009) is a chimeric, humanized IgG1/k MAb that targets the cell surface mesothelin (MSLN). Mesothelin is a glycosylphosphatidyl inositol (GPI)-anchored membrane glycoprotein, which is present in a restricted set of normal adult tissues such as the mesothelium .
loading...
    loading...
Cat. No.: HY-P99352
CAS No.: 1954758-84-9
Synonyms: Anti-MSLN Antibody

Research Areas:  

Cancer

Anetumab (Anti-MSLN Antibody) is a fully humanized anti mesothelin (MSLN) IgG1 antibody. Anetumab (Anti-MSLN Antibody) can be used to synthesize the ADC molecule Anetumab ravtansine (HY-141606). Anetumab (Anti-MSLN Antibody) can be used for the research of cancer .
loading...
    loading...
Cat. No.: HY-141606
CAS No.: 1375258-01-7
Purity:  99.36%
Synonyms: BAY 94-9343
Anetumab ravtansine (BAY 94-9343) is a selective and highly potent antibody-drug conjugate (ADC) to target maytansinoid tubulin. Anetumab ravtansine consists of a human anti-mesothelin antibody conjugated to the maytansinoid tubulin inhibitor DM4. Anetumab ravtansine shows antitumor efficacy correlated with the amount of mesothelin expressed in patient-derived xenograft tumor models .
loading...
    loading...
Cat. No.: HY-P990833

Target:  

Mesothelin

Research Areas:  

Cancer

Anti-Mesothelin Antibody (YP218) is a kind of rabbit IgG chimeric antibody, targeting to human Mesothelin. Anti-Mesothelin Antibody (YP218) reacts with a epitope in the C-terminal end close to the tumor cell surface of human mesothelin (MSLN). Anti-Mesothelin Antibody (YP218) can be used for the research of cancer, such as A431/H9 tumor .
loading...
    loading...
Cat. No.: HY-P991088

Target:  

CD3

Research Areas:  

Cancer

HPN536 is a trispecific, T-cell-activating protein-based construct, which binds to mesothelin-expressing tumor cells, CD3ε on T cells, and to serum albumin. HPN536 specifically redirects T cells for potent redirected lysis of mesothelin-expressing cancer cells with concomitant T-cell activation .
loading...
    loading...
Cat. No.: HY-171269
Research Areas:  

Cancer

Anetumab-MMAE is an antibody-drug conjugate (ADC) (Anetumab antibody (HY-P99352), Linker: VC linker, Payload: MMAE (HY-15162)). Anetumab is an anti-mesothelin (MSLN) antibody.
loading...
    loading...
Cat. No.: HY-P990466

Target:  

Mesothelin

Research Areas:  

Inflammation/Immunology

Anti-Mesothelin Antibody is a humanized antibody expressed in CHO that targets Mesothelin. The Anti-Mesothelin Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. For isotype control of the Anti-Mesothelin Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).
loading...
    loading...
Cat. No.: HY-P991315
Synonyms: RG7600 antibody

Research Areas:  

Cancer

Anti-MSLN/Mesothelin (h7D9.v3) is a human monoclonal antibody (mAb) targeting MSLN. Anti-MSLN/Mesothelin (h7D9.v3) can be used in ovarian cancer, mesothelioma, and pancreatic cancer research .
loading...
    loading...
Cat. No.: HY-P990558
Synonyms: BMS-986148 antibody

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

BMS-986021 (BMS-986148 antibody) is a human monoclonal antibody expressed in CHO, targeting Mesothelin. BMS-986021 has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 144.46 kDa. For the isotype control of BMS-986021, refer to Human IgG1 kappa, Isotype Control (HY-P99001).
loading...
    loading...
Cat. No.: HY-139325A
Purity:  96.03%
Research Areas:  

Cancer

NHS-Modified MMAF (intermediat 210) TFA is an intermediate which can be used for producing the anti-mesothelin binder-agent conjugates (ADCs) .
loading...
    loading...
Cat. No.: HY-139325
CAS No.: 1404073-10-4
Research Areas:  

Others

NHS-Modified MMAF (WO2012143499A2, intermediat 210) is an intermediate which can be used for producing the anti-mesothelin binder-agent conjugates (ADCs) .
loading...
    loading...
Cat. No.: HY-185561
Synonyms: RC88
Target:  

Mesothelin

Research Areas:  

Cancer

Misitatug blivedotin (RC88) is an antibody-drug conjugate (ADC) targeting mesothelin (MSLN). Misitatug blivedotin binds to mesothelin and exhibits dose‐dependent antitumor activity. Misitatug blivedotin can be used for the research of ovarian cancer, non-squamous non-small-cell lung carcinoma, cervical cancer .
loading...
    loading...
Cat. No.: HY-P78620
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MSLN; mesothelin; MPF
Species:  
Rat
Source:  
loading...
    loading...
Cat. No.: HY-P704787
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: mesothelin; Msln; Mes; Mpf
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P78834
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MSLN; mesothelin; MPF
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P78644
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MSLN; mesothelin; MPF
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P85960
Synonyms: mesothelin; CAK1 antigen; Pre-pro-megakaryocyte-potentiating factor; [Cleaved into: Megakaryocyte-potentiating factor; MPF; mesothelin, cleaved form]

Host:  

Mouse

Application:  

IHC-P, WB, ICC/IF, ELISA

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-P70856
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: mesothelin; Msln; Mes; Mpf
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P701259
Synonyms: MSLN; mesothelin; MPF
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P77797
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: MSLN; CAK1; mesothelin; MPF; MPFSMRP; SMR
Species:  
Source:  
loading...
    loading...