5 Results for "

nephrectomy

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "nephrectomy" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-N1472
CAS No.: 88182-33-6
Levistolide A is an apoptosis inducer and a PEDV virus inhibitor. Levistolide A can induce apoptosis in colon cancer cells and suppress the replication of porcine epidemic diarrhea virus (PEDV) by promoting ROS generation. Levistolide A activates peroxisome proliferator-activated receptor γ (PPARγ) in N2a/APP695swe cells and reduces excessive phosphorylation of tau through the GSK3α/β pathway, improving symptoms in Alzheimer’s mice. Levistolide A improves kidney damage in 5/6 nephrectomy (Nx) mice by inhibiting the RAS,TGF-β1/Smad, and MAPK pathways .
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3
3 Cited Publications
Cat. No.: HY-14858
CAS No.: 251945-92-3
Purity:  99.93%
Synonyms: SLV 320
Target:  

Adenosine Receptor

Research Areas:  

Cardiovascular Disease

Derenofylline (SLV 320) is a potent, selective and orally active adenosine A1 receptor antagonist, with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively. Derenofylline suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats .
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2
2 Cited Publications
Cat. No.: HY-B1472
CAS No.: 56-47-3
Synonyms: 11-Deoxycorticosterone acetate; DOC acetate; Cortexone acetate
Deoxycorticosterone acetate (DOCA) is an adrenocortin, acts as a precursor to aldosterone. Deoxycorticosterone acetate is a mineralocorticoid receptor agonist. Deoxycorticosterone acetate can cause severe renal injury, including inflammation, fibrosis, glomerular damage, and proteinuria .
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Cat. No.: HY-14858R
CAS No.: 251945-92-3
Synonyms: SLV 320 (Standard)
Derenofylline (Standard) is the analytical standard of Derenofylline. This product is intended for research and analytical applications. Derenofylline (SLV 320) is a potent, selective and orally active adenosine A1 receptor antagonist, with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively. Derenofylline suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats .
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Cat. No.: HY-163148
CAS No.: 2924181-77-9
Research Areas:  

Cardiovascular Disease

PHD-IN-3 (Compound 15) is an orally active PHD inhibitor. PHD-IN-3 can be used in the study of anemia associated with chronic kidney disease .
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