75 Results for "

nerve growth factor (NGF)

" in MedChemExpress (MCE) Product Catalog:
Products (75)

75 Results for "nerve growth factor (NGF)" in MCE Product Catalog:

11
11 Publications Verification
Cat. No.: HY-18314
CAS No.: 504433-23-2
Target:  

Trk Receptor Apoptosis

Research Areas:  

Neurological Disease Cancer

GW 441756 is a potent and specific nerve growth factor (NGF) receptor tyrosine kinases A (TrkA) inhibitor (IC50=2 nM), which eliminates the BmK NSPK-induced neurite outgrowth .
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5
5 Cited Publications
Cat. No.: HY-P73316
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NGF; Beta-NGF; Prev. NGFB; Pro-nerve growth factor Long; Beta-nerve growth factor; HSAN5; nerve growth factor (Beta Polypeptide); nerve growth factor; nerve growth factor, Beta Subunit
Species:  
Human
Source:  
CHO
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4
4 Cited Publications
Cat. No.: HY-108466
CAS No.: 37854-59-4
Purity:  98.63%
Target:  

Apoptosis

Research Areas:  

Neurological Disease Cancer

Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 μM. Ro 08-2750 inhibits NGF binding to p75 NTR selectively over TRKA . Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM .
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4
4 Cited Publications
Cat. No.: HY-P702778
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NGF; Beta-NGF; Prev. NGFB; Pro-nerve growth factor Long; Beta-nerve growth factor; HSAN5; nerve growth factor (Beta Polypeptide); nerve growth factor; nerve growth factor, Beta Subunit
Species:  
Rat
Source:  
HEK293
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2
2 Cited Publications
Cat. No.: HY-133968
CAS No.: 474-63-5
Purity:  99.48%
Synonyms: Ostreasterol
24-Methylenecholesterol (Ostreasterol) is a regulator targeting acyl-CoA cholesterol acyltransferase (ACAT) with anti-aging and neuroprotective effects. 24-Methylenecholesterol mimics the effects of nerve growth factor (NGF), can extend yeast lifespan through an anti-oxidative stress mechanism, and exhibits neuroprotective activity in PC12 cells. 24-Methylenecholesterol can reduce intracellular reactive oxygen species (ROS) and malondialdehyde (MDA) levels, activate anti-oxidative stress pathways (such as UTH1, SOD-related genes), and promote synaptic growth .
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2
2 Cited Publications
Cat. No.: HY-17622
CAS No.: 263251-78-1
Synonyms: MIM-D3
Target:  

Trk Receptor

Research Areas:  

Inflammation/Immunology

Tavilermide is a selective, partial agonist of TrkA, or a nerve growth factor (NGF) mimetic.
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2
2 Cited Publications
Cat. No.: HY-110166
CAS No.: 77422-99-2
Purity:  ≥99.0%
Target:  

Trk Receptor

Research Areas:  

Neurological Disease

PD 90780 is a non peptide antagonist of nerve growth factor (NGF). PD 90780 interacts with NGF, prevents NGF binds with p75 NTR. PD 90780 inhibits NGF-p75 NTR interaction with IC50s of 23.1 and 1.8 μM in PC12 cells and PC12 nnr5 cells, respectively .
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2
2 Cited Publications
Cat. No.: HY-P73317
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NGF; Beta-NGF; Prev. NGFB; Pro-nerve growth factor Long; Beta-nerve growth factor; HSAN5; nerve growth factor (Beta Polypeptide); nerve growth factor; nerve growth factor, Beta Subunit
Species:  
Mouse
Source:  
CHO
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2
2 Cited Publications
Cat. No.: HY-P70456
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NTF3; Neurotrophin-3; Neurotrophin 3; NGF-2; NGF2; HDNF; nerve growth factor 2; NT-3; Neurotrophic factor; NT3
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-A0015
CAS No.: 190786-44-8
Bepotastine besilate is a selective and orally active second-generation histamine H1 receptor antagonist, can suppress the expression of nerve growth factor (NGF). Bepotastine besilate has the potential for allergic rhinitis, allergic conjunctivitis and urticaria/pruritus research .
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1
1 Cited Publications
Cat. No.: HY-I0021
CAS No.: 125602-71-3
Target:  

Histamine Receptor

Bepotastine is a selective and orally active second-generation histamine H1 receptor antagonist, can suppress the expression of nerve growth factor (NGF). Bepotastine has the potential for allergic rhinitis, allergic conjunctivitis and urticaria/pruritus research .
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Cat. No.: HY-P99297
CAS No.: 2171034-69-6
Synonyms: ZTS-00508841

Target:  

Trk Receptor

Research Areas:  

Inflammation/Immunology

Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) targeting nerve growth factor (NGF). Bedinvetmab inhibits NGF interaction with tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR) receptors. Bedinvetmab can be used for the research of osteoarthritis pain in dogs .
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Cat. No.: HY-P99677
CAS No.: 2447755-72-6
Synonyms: ZTS-00075623
Izenivetmab (ZTS-00075623) is an anti-NGFB IgG2κ monoclonal antibody. Izenivetmab shows anti-inflammatory and analgesic effects by targeting anti-nerve growth factor (NGF). Izenivetmab can be used for the research of osteoarthritis .
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Cat. No.: HY-P99627
CAS No.: 1708936-80-4
Synonyms: NV-02; PG110; ABT-110

Target:  

Trk Receptor

Research Areas:  

Inflammation/Immunology

Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a Kd of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats .
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Cat. No.: HY-P99195
CAS No.: 1190239-42-9
Synonyms: REGN-475; SAR-164877

Target:  

Trk Receptor

Research Areas:  

Inflammation/Immunology

Fasinumab (Anti-Human NGF) is a human IgG4 monoclonal antibody to nerve growth factor (NGF). Fasinumab can be used in acute sciatica and knee osteoarthritis (OA) studies .
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Cat. No.: HY-N0380
CAS No.: 23720-80-1
Nardosinone, isolated from Nardostachys chinensis, is the first enhancer of the neuritogenic action of dbcAMP and staurosporine. Nardosinone may become a useful pharmacological tool for studying the mechanism of action of not only nerve growth factor (NGF) but also both the neuritogenic substances .
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Cat. No.: HY-NP144
CAS No.: 93928-24-6
Nerve Growth Factor 7S,murine submaxillary gland is a high-molecular-weight α2β2γ2 neurotrophic factor complex isolated from murine submaxillary glands. Nerve Growth Factor 7S,murine submaxillary gland prevents the binding of active β-NGF dimers to neuronal receptors by sequestering the receptor-interacting region of β-NGF within the complex. Nerve Growth Factor 7S,murine submaxillary gland lacks neurotrophic activity due to the sequestration of β-NGF dimers and the occlusion of receptor-binding sites. Nerve Growth Factor 7S,murine submaxillary gland can be used in research related to neurodegenerative diseases .
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Cat. No.: HY-N12566
CAS No.: 156101-10-9
Erinacin B is a active product that can be extracts from the mycelia of Hericium erinaceum. Erinacin B shows potent stimulating activity of nerve growth factor (NGF)-synthesis .
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Cat. No.: HY-117517
CAS No.: 141731-76-2
NG-012, potentiator of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542. NG-012 potentiates the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12) .
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Cat. No.: HY-N3938
CAS No.: 110414-77-2
Gelsemiol is the main active ingredient in Verbena littoralis H. B. K.. Gelsemiol enhanced nerve growth factor (NGF) -induced axonal elongation in PC12D cells .
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