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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
152 Results for "
oleic
" in MedChemExpress (MCE) Product Catalog:
Products (152)
152 Results for "oleic" in MCE Product Catalog:
75
75 Publications Verification
Synonyms: 9-cis-Octadecenoic acid; 9Z-Octadecenoic acid
75
75 Publications Verification
Synonyms: Sodium oleate; 9-cis-Octadecenoic acid sodium; 9Z-Octadecenoic acid sodium
3
3 Cited Publications
Synonyms: N-Oleoylethanolamide; Oleamide MEA; oleic acid monoethanolamide
Category:
Cardiovascular Disease Human Gut Microbiota Metabolites Natural Products Microorganisms Endogenous metabolite Disease Research Fields
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3
3 Cited Publications
Synonyms: Dioleoylphosphatidylglycerol sodium
3
3 Cited Publications
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Research Areas:
DC260126 is a potent antagonist of GPR40 (FFAR1). DC260126 dose-dependently inhibits GPR40-mediated Ca 2+ elevations stimulated by linoleic acid, oleic acid, palmitoleic acid and lauric acid (IC50: 6.28, 5.96, 7.07, 4.58 μM, respectively) . DC260126 could protect MIN6 β cells from palmitate-induced ER stress and apoptosis .
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Bifendate (DDB), extracted from Schisandrae chinensis, is an orally active anti-HBV agent against chronic hepatitis B. Bifendate inhibits ATG5-dependent autophagy and attenuates oleic acid-induced lipid accumulation with anti-oxidant properties in vitro. Bifendate can decrease alanine transaminase (ALT) level in mice. Bifendate attenuates hepatic steatosis in cholesterol/bile salt- and high-fat diet-induced hypercholesterolemia in mice. Bifendate potently increases the activity of cytochrome proteins (CYPs) and reverse P-gp-mediated multi-drug resistance (MDR) .
1
1 Cited Publications
Cat. No.: HY-N1446S2
CAS No.: 287100-82-7
Synonyms: 9-cis-Octadecenoic acid-13C18; 9Z-Octadecenoic acid-13C18
1
1 Cited Publications
Cat. No.: HY-N1446S1
CAS No.: 5711-29-5
Synonyms: 9-cis-Octadecenoic acid-d2; 9Z-Octadecenoic acid-d2
1
Category:
Ketones, Aldehydes, Acids Other Diseases Artemisia lactiflora Wall. ex DC. Plants Umbelliferae Endogenous metabolite Disease Research Fields
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1
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1
1
1 Cited Publications
Cat. No.: HY-W399297
CAS No.: 566-17-6
Synonyms: 7α,12α-Dihydroxycholanoic acid
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1
1 Cited Publications
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LEI110 is a pan-inhibitor of the HRASLS family and an inhibitor of AP-2α, with a Ki of 20 nM against PLA2G16. LEI110 exhibits inhibitory activity against PLA2G16, HRASLS2, RARRES3 and iNAT, with pIC50 values of 7.0, 6.8, 6.8 and 7.6, respectively. LEI110 binds to the active site of PLA2G16, reduces intracellular arachidonic acid levels, and attenuates oleic acid-induced lipolysis. LEI110 stabilizes AP-2α, impairs its DNA-binding ability, inhibits the transcription of DNA damage repair genes, induces the accumulation of oxidative DNA damage, suppresses cell proliferation and clonogenicity, and sensitizes HCC cells to DNA-damaging agents. LEI110 can be used in research related to obesity, fatty liver disease, the common cold and hepatocellular carcinoma .
Cat. No.: HY-N1446S5
CAS No.: 2687960-84-3
Synonyms: 9-cis-Octadecenoic acid-d9; 9Z-Octadecenoic acid-d9
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Oleic acid alkyne is Oleic acid (HY-N1446) with an acetylene group. The terminal alkyne group can be used for click chemical ligation reactions. Oleic acid can be hydroxylated by a microsomal cytochrome P-450-dependent system (ω-OAH). Through click chemistry reactions, fluorescent or biotin-labeled oleic acid can be introduced to analyze its metabolism and biological activity.
Cat. No.: HY-121457
CAS No.: 875685-44-2
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9-Nitrooleate, a nitro fatty acid, is a nitro derivative of Oleic acid (HY-N1446). 9-Nitrooleate has potential for use in vascular disease research.
Synonyms: 2-Hydroxyoleic acid; 2-OHOA; LAM561
(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a synthetic oleic acid (OA) derivative that binds to the plasma membrane and alters lipid organization. (Rac)-Idroxioleic acid has anti-tumor effect .
Cat. No.: HY-N1446S
CAS No.: 82005-44-5
Synonyms: 9-cis-Octadecenoic acid-13C; 9Z-Octadecenoic acid-13C
Category:
Ricinus communis L. Ketones, Aldehydes, Acids Metabolic Disease Euphorbiaceae Plants Disease Research Fields
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Synonyms: Lyso-PE (egg); LPE (egg); L-α-lysophosphatidylethanolamine
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Research Areas:
Lysophosphatidylethanolamines, egg (Lyso-PE (egg); LPE (egg); L-α-lysophosphatidylethanolamine) is a naturally occurring lysophospholipid isolated from purified egg phosphatidylcholine. Lysophosphatidylethanolamines, egg acts as a hepatic lipid biomarker in oleic acid-induced hepatocytes. The level of Lysophosphatidylethanolamines, egg decreases in mice fed a high-fat diet. Lysophosphatidylethanolamines, egg can be used in studies related to non-alcoholic fatty liver disease and hyperlipidemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
