50 Results for "

pepide

" in MedChemExpress (MCE) Product Catalog:
Products (50)

50 Results for "pepide" in MCE Product Catalog:

6
6 Publications Verification
Cat. No.: HY-P0078
CAS No.: 141136-83-6
Synonyms: PAR-1 agonist peptide; Thrombin Receptor Activator Peptide 6
TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective protease activating receptor 1 (PAR1) agonist. TRAP-6 activates human platelets via the thrombin receptor. TRAP-6 shows no activity at PAR4 .
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6
6 Publications Verification
Cat. No.: HY-P1029
CAS No.: 224579-74-2
Target:  

Myosin CaMK Autophagy

Research Areas:  

Others

MLCK inhibitor peptide 18 is a myosin light chain kinase (MLCK) inhibitor with an IC50 of 50 nM, and inhibits CaM kinase II only at 4000-fold higher concentrations.
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3
3 Cited Publications
Cat. No.: HY-P3414A
Target:  

Proteasome

Research Areas:  

Neurological Disease

Proteasome-activating peptide 1 TFA is a peptide and a potent proteasome activator. Proteasome-activating peptide 1 TFA increases the chymotrypsin-like proteasomal catalytic activity and, consequently, proteolytic rates both in vitro and in culture. Proteasome-activating peptide 1 TFA prevents protein aggregation in a cellular model of amyotrophic lateral sclerosis .
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1
1 Cited Publications
Cat. No.: HY-P3532
Synonyms: [pGlu1]-FGL peptide acetate; [Pyr1]-FGL peptide acetate
Target:  

Inhibitory Antibodies

Research Areas:  

Neurological Disease

[Glp1]-FGL peptide acetate is a neural cell adhesion molecule (NCAM) derived motif and can be used for the research of neurogenesis .
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1
1 Cited Publications
Cat. No.: HY-P84648
Synonyms: Brain natriuretic peptide 32 antibody; Brain type natriuretic peptide antibody; Gamma brain natriuretic peptide antibody; Natriuretic peptide B antibody; Natriuretic peptide precursor B antibody; natriuretic peptide, brain type antibody; Natriuretic peptides B antibody; natriuretic protein antibody; NPPB antibody

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P0307
CAS No.: 188842-14-0
Synonyms: Penetratin peptide
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Antennapedia Peptide (Penetratin peptide) is a 16 amino acid peptide, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia and is a member of the family of cell-penetrating peptides.
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Cat. No.: HY-P10476
CAS No.: 1621169-52-5
Target:  

TGF-beta/Smad

Research Areas:  

Others

Myostatin inhibitory peptide 2 (compd 2) is a myostatin inhibitor with a Kd of 35.9 nM. Myostatin inhibitory peptide 2 can be used for researches of muscle atrophic disorders .
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Cat. No.: HY-P0277
CAS No.: 168635-85-6
Synonyms: CEA peptide
Carcinoembryonic antigen peptide 1 (CEA peptide) is a 9-amino acid HLA-A0201-binding cytotoxic T lymphocyte (CTL) epitope peptide derived from carcinoembryonic antigen (CEA). The IC50 of Carcinoembryonic antigen peptide 1 binding to HLA-A0201 is 2 μM. Carcinoembryonic antigen peptide 1 binds to HLA-A0201 to form a peptide-MHC I complex, which is recognized by the T cell receptor (TCR) of CAP1-specific CD8 + CTLs, thereby inducing antigen-specific T cell activation, IFN-γ production, and CTL-mediated lysis of target cells. Carcinoembryonic antigen peptide 1 is used in research on CEA-specific CTL responses and colorectal cancer .
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Cat. No.: HY-P10242
CAS No.: 1621169-56-9
Target:  

TGF-beta/Smad

Research Areas:  

Others

Myostatin inhibitory peptide 7 is a 23 amino acids peptide, which is derived from amino acids 21 to 43 of the mouse myostatin prodomain. Myostatin inhibitory peptide 7 inhibits myostatin with a Kd of 29.7 nM. Myostatin inhibitory peptide 7 can be used for researches of muscle atrophic disorders .
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Cat. No.: HY-P10409
CAS No.: 1191923-93-9
Synonyms: Small humanin-like peptide 2
SHLP2 (Small humanin-like peptide 2) is a small molecule peptide encoded by mitochondrial DNA, belonging to mitochondria derived peptide. SHLP2 has the activity of regulating apoptosis and inhibits cell death. SHLP2 binds to mitochondrial complex 1. SHLP2 improves mitochondrial metabolism by increasing respiration and biogenesis, reducing ROS, and decreasing mtDNA oxidation. SHLP2 also regulated energy homeostasis through the activation of hypothalamic neurons. SHLP2 can be used in the study of diseases related to mitochondrial dysfunction and anti-aging diseases, such as age-related macular degeneration and Parkinson’s disease .
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Cat. No.: HY-12537
CAS No.: 32908-73-9
Purity:  98.26%
Peptide 401, a potent mast cell degranulating factor from bee venom, suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, and 5-HT).
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Cat. No.: HY-P10422A
Synonyms: ML-peptide, Multi-Leucine (ML)-peptide triacetate
Target:  

Autophagy

Research Areas:  

Cancer

Multi-Leu peptide (ML-peptide) triacetate is a potent inhibitor of PACE4 (Ki=22 nM). Multi-Leu peptide triacetate can competitively bind to the active site of PACE4 by simulating the substrate sequence of PACE4, thereby inhibiting its catalytic activity. Multi-Leu peptide triacetate can be used to study the specific mechanism of PACE4 in the development of prostate cancer .
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Cat. No.: HY-P1805
CAS No.: 104041-80-7
Target:  

Calmodulin

Research Areas:  

Neurological Disease

Calmodulin Binding Peptide 1 is a high-affinity (pM) CaM-binding peptide derived from smooth muscle myosin light chain kinase (MLCK peptide). The interface of the complex formed by Calmodulin Binding Peptide 1 and Ca 2+-CaM can be specifically bound by small-molecule inhibitors, serving as a key target for selective regulation of smooth muscle contraction and development of anti-CaM drugs .
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Cat. No.: HY-P0306
CAS No.: 125720-21-0
Synonyms: Heparin Binding Peptide
Target:  

Others

Research Areas:  

Cardiovascular Disease

Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin. It promotes assembly of mesenchymal stem cell (MSC) spheroids into larger aggregates. Fibronectin Adhesion-promoting Peptide directly promotes the adhesion, spreading, and migration of endothelial cells by reacting with heparin binding domains of cells .
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Cat. No.: HY-P4858
CAS No.: 41475-27-8
Target:  

GSK-3 Wnt

Research Areas:  

Cancer

C-Peptide 1 (rat), a peptide, is aβ-catenin/GSK-3β activator. C-Peptide 1 (rat) can regulate the Wnt/β-catenin signaling pathway. C-Peptide 1 (rat) can be used for the research of cancer .
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Cat. No.: HY-P0122B
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

iRGD peptide 1 TFA is the prototypic tumor-specific tissue-penetrating peptide, which delivers agents deep into extravascular tumor tissue. iRGD peptide 1 TFA has anti-metastatic activity .
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Cat. No.: HY-P3586
CAS No.: 859216-15-2
Synonyms: Hunter-killer peptide ao; Prohibitin-targeting peptide 1; prohibitin-TP01; Adipotide
Target:  

Apoptosis

Research Areas:  

Cancer

HKPao (Hunter-killer peptide ao) is a biologically active peptide. HKPao (Hunter-killer peptide ao) has anti-obesity and anti-tumor pro-apoptotic activity to cause release of cytochrome c from vesicles .
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Cat. No.: HY-P1186
CAS No.: 2990-43-4
Synonyms: Eledoisin-Related Peptide; Eledoisin RP
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

Eledoisin Related Peptide is a Substance P analog that excites neurons and triggers behavioral responses. Eledoisin Related Peptide is also a tachykinin receptor ligand.
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Cat. No.: HY-P10414A
Synonyms: KP1 (human) hydrochloride
Target:  

TGF-β Receptor

Research Areas:  

Infection Endocrinology

Klotho-derived peptide 1 hydrochloride (KP1 (human) hydrochloride) is a polypeptide with multiple activities including senescence inhibition and renal protection. Klotho-derived peptide 1 hydrochloride binds to TβR2 and ATAD3A, with a Kd value of 1.41 μM for binding to human TβR2 and a Kd value of 0.319 μM for binding to ATAD3A. By binding to TβR2, Klotho-derived peptide 1 hydrochloride blocks the TGF-β/Smad3 and downstream TGF-β signaling pathways, inhibits the expression of miR-223-3p, induces the expression of lncRNA-TUG1, restores endogenous Klotho at the post-transcriptional level, inhibits cellular senescence markers, fibroblast activation and renal tubular epithelial cell apoptosis, blocks cytochrome c release and caspase activation, maintains the integrity of mitochondrial ultrastructure, and restores mitochondrial protein levels. Klotho-derived peptide 1 hydrochloride enters renal tubular epithelial cells via endocytosis, protects against nephrotoxic and hypoxic injuries, and recapitulates the renal protective and anti-fibrotic effects of full-length Klotho. Klotho-derived peptide 1 hydrochloride can be used in research related to kidney diseases such as chronic kidney disease and SARS-CoV-2-associated acute kidney injury .
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Cat. No.: HY-P10414
Synonyms: KP1 (human)
Target:  

TGF-β Receptor

Research Areas:  

Infection Endocrinology

Klotho-derived peptide 1 (KP1 (human)) is a polypeptide with multiple activities including senescence inhibition and renal protection. Klotho-derived peptide 1 binds to TβR2 and ATAD3A, with a Kd value of 1.41 μM for binding to human TβR2 and a Kd value of 0.319 μM for binding to ATAD3A. By binding to TβR2, Klotho-derived peptide 1 blocks the TGF-β/Smad3 and downstream TGF-β signaling pathways, inhibits the expression of miR-223-3p, induces the expression of lncRNA-TUG1, restores endogenous Klotho at the post-transcriptional level, inhibits cellular senescence markers, fibroblast activation and renal tubular epithelial cell apoptosis, blocks cytochrome c release and caspase activation, maintains the integrity of mitochondrial ultrastructure, and restores mitochondrial protein levels. Klotho-derived peptide 1 enters renal tubular epithelial cells via endocytosis, protects against nephrotoxic and hypoxic injuries, and recapitulates the renal protective and anti-fibrotic effects of full-length Klotho. Klotho-derived peptide 1 can be used in research related to kidney diseases such as chronic kidney disease and SARS-CoV-2-associated acute kidney injury .
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