1 Result for "

polyploid-specific

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "polyploid-specific" in MCE Product Catalog:

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1 Cited Publications
Cat. No.: HY-U00441
CAS No.: 7029-89-2
Target:  

MDM-2/p53 Apoptosis

Research Areas:  

Cancer

DPBQ activates p53 and triggers apoptosis in a polyploid-specific manner, but does not inhibit topoisomerase or bind DNA. DPBQ elicits expression and phosphorylation of p53 and this effect is specific to tetraploid cells .
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