Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
rat peritoneal mast cells
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "rat peritoneal mast cells" in MCE Product Catalog:
11
11 Cited Publications
Cat. No.: HY-B0320A
CAS No.: 15826-37-6
Synonyms: Cromoglycate disodium; Cromoglicic acid disodium; FPL-670
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Cromolyn (Cromoglycate) disodium is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn disodium is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn disodium can be used in the research of bronchial asthma. In addition, Cromolyn disodium has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects .
11
11 Cited Publications
Cat. No.: HY-B1619
CAS No.: 16110-51-3
Synonyms: Cromoglycate; Cromoglicic acid; FPL-670 free acid
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Cromolyn (Cromoglycate) is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn can be used in the research of bronchial asthma. In addition, Cromolyn has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects .
Research Areas:
Reproterol is a selective β2-adrenoceptor agonist and cAMP phosphodiesterase (PDE) inhibitor. Reproterol inhibits adenylate cyclase-induced phosphodiesterase activity. Reproterol inhibits histamine release from mast cells. Reproterol is applicable to research related to asthma .
Cat. No.: HY-P1793
CAS No.: 83471-50-5
Research Areas:
Cat. No.: HY-N3007A
CAS No.: 25515-46-2
Target:
Cat. No.: HY-P2706
CAS No.: 64704-41-2
Target:
Research Areas:
Cat. No.: HY-P1793A
Research Areas:
Cat. No.: HY-B1619R
CAS No.: 16110-51-3
Synonyms: Cromoglycate (Standard); Cromoglicic acid (Standard); FPL-670 free acid (Standard)
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Cromolyn (Standard) is the analytical standard of Cromolyn. This product is intended for research and analytical applications. Cromolyn (Cromoglycate) is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn can be used in the research of bronchial asthma. In addition, Cromolyn has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects .
Cat. No.: HY-N12210
CAS No.: 2363714-40-1
Target:
Cat. No.: HY-N15230
CAS No.: 243835-63-4
Category:
Quinones Anthraquinones Caesalpiniaceae Cassia obtusifolia (L.) H. S. Irwin & Barneby Plants
Target:
Cat. No.: HY-N11691
CAS No.: 67526-94-7
Synonyms: Thapsigargicine
Target:
Cat. No.: HY-N12295
CAS No.: 114912-35-5
Category:
Triterpenes Tetracyclic Triterpenoids Terpenoids Acanthopanax senticosus (Rupr. et Maxim.) Harms Plants Araliaceae
Target:
Cat. No.: HY-137614C
Target:
Research Areas:
Rp-GTPαS tetrasodium is a phosphorothioate analogue of Guanosine triphosphate (GTP) (HY-113225) that can activate calcium release and secretion in single rat peritoneal mast cells .
Cat. No.: HY-N15704
CAS No.: 218155-49-8
Category:
Monophenols Ketones, Aldehydes, Acids Caesalpiniaceae Cassia obtusifolia (L.) H. S. Irwin & Barneby Phenols Plants
Target:
Cat. No.: HY-126127
CAS No.: 72364-91-1
Target:
Research Areas:
BRL 22321 free base is a stabilizer with similar mast cell stabilizing activity to Cromolyn sodium (HY-B0320A) and also has some smooth muscle relaxant activity. BRL 22321 free base is more potent than Cromolyn sodium (HY-B0320A) in inhibiting rat passive cutaneous and peritoneal anaphylaxis and antigen-induced histamine release from passively sensitized rat peritoneal cells .
Cat. No.: HY-123432
CAS No.: 130838-11-8
Target:
Research Areas:
AHR-13268D is an oral active antiallergic and antihistaminic agent, with bioavailable approximately 88%. AHR-13268D is a potent inhibitor of histamine release from rat peritoneal mast cells, with the IC50 of 0.51 nM .
Cat. No.: HY-183237
CAS No.: 112851-89-5
Target:
Research Areas:
Oxphaman is a pea lipoxygenase inhibitor with an IC50 of 140 nM against pea lipoxygenase. Oxphaman inhibits protamine sulfate-induced degranulation of rat peritoneal mast cells .
Cat. No.: HY-163061
CAS No.: 101193-40-2
Target:
Research Areas:
Quinotolast is an orally active antiallergic agent. Quinotolast inhibits histamine release from rat peritoneal cells. Quinotolast inhibits cutaneous cromoglycate in guinea pig model. Quinotolast has inhibitory effect on histamine and peptide leukotrienes release from guinea pig lung fragments and mouse cultured mast cells. Quinotolast can be studied in allergy-related research .
Cat. No.: HY-P11163
CAS No.: 255720-68-4
Target:
Research Areas:
Cat. No.: HY-182414
CAS No.: 81907-78-0
Target:
Research Areas:
NCO-650 free base is an antiallergic agent that acts by inhibiting tryptase, a key trypsin-like protease in mast cells. NCO-650 free base inhibits mast cell histamine release, increases intracellular cAMP levels in mast cells, suppresses bronchoconstriction, and prevents decreases in perfusion pressure and systemic blood pressure. NCO-650 free base is applicable to the research of allergic diseases and bronchial asthma .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
