25515-46-2
25515-46-2
Chemical Structure
(E)-Naringenin chalcone
- CAS No.: 25515-46-2
- Formula:C15H12O5
- Molecular Weight:272.26
IUPAC Name: (E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one
InChIKey: YQHMWTPYORBCMF-ZZXKWVIFSA-N
SMILES: OC(C=C1)=CC=C1/C=C/C(C2=C(C=C(O)C=C2O)O)=O
Biological Activity: (E)-Naringenin chalcone is an orally active anti-allergic agent. (E)-Naringenin chalcone also has antioxidant, anti-inflammatory activities. (E)-Naringenin chalcone can improve adipocyte functions. (E)-Naringenin chalcone inhibits histamine release from rat peritoneal mast cell[1][2][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(E)-Naringenin chalcone | 98.87% | (E)-Naringenin chalcone is an orally active anti-allergic agent. (E)-Naringenin chalcone also has antioxidant, anti-inflammatory activities. (E)-Naringenin chalcone can improve adipocyte functions. (E)-Naringenin chalcone inhibits histamine release from rat peritoneal mast cell. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-N3007Naringenin chalcone -
Similarity Score 0.87
HY-N4058RHelichrysetin (Standard) -
Similarity Score 0.85
HY-N7515Pinocembrin chalcone -
Similarity Score 0.85
HY-N7515A(E)-Pinocembrin chalcone -
Similarity Score 0.85
HY-N9551Eriodictyol chalcone -
Similarity Score 0.84
HY-N0102RIsoliquiritigenin (Standard) -
Similarity Score 0.83
HY-N130642,2′,4,4′-Tetrahydroxychalcone -
Similarity Score 0.83
HY-16558RButein (Standard) -
Similarity Score 0.82
HY-W749844Homoeriodictyol chalcone -
Explore the MedChemAI to find more analogs
References
- [1]. Taichi Yamamoto, et al. Anti-allergic activity of naringenin chalcone from a tomato skin extract. Biosci Biotechnol Biochem. 2004 Aug;68(8):1706-11. [Content Brief]
- [2]. Taro Horiba, et al. Naringenin chalcone improves adipocyte functions by enhancing adiponectin production. Mol Cell Endocrinol. 2010 Jul 29;323(2):208-14. [Content Brief]
- [4]. Shizuka Hirai, et al. Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages. Life Sci. 2007 Sep 29;81(16):1272-9. [Content Brief]
