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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
resection
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "resection" in MCE Product Catalog:
Synonyms: HRX-0215
Darizmetinib (HRX-0215) is an orally active, potent and selective inhibitor of mitogen-activated protein kinase kinase 4 (MKK4). Darizmetinib leads to enhancement of the MKK7 and JNK1 signaling pathways, thereby activating the transcription factors ATF2 and ELK1, promoting cell proliferation and liver regeneration. Darizmetinib is promising for research of preventing liver failure after extensive oncological liver resections or transplantation of small liver grafts .
Referencia número: HY-P1714
No. CAS: 1295353-98-8
Synonyms: FE 203799
Target:
Áreas de investigación:
Referencia número: HY-174143
No. CAS: 1111188-09-0
EXO1-IN-1 is a human exonuclease 1 (EXO1) inhibitor (IC50 = 15.7 μM). EXO1-IN-1 inhibits DNA end resection, promotes the accumulation of DNA double-strand breaks, and triggers S-phase polyamylation. EXO1-IN-1 induces apoptosis (Apoptosis) in BRCA1-deficient breast cancer cells. EXO1-IN-1 suppresses the growth of BRCA1-deficient breast cancer xenografts. EXO1-IN-1 can be used in research related to BRCA1-deficient breast cancer .
Target:
Referencia número: HY-P1714A
Synonyms: FE 203799 TFA
Target:
Áreas de investigación:
Referencia número: HY-149298
No. CAS: 2946600-14-0
PSMA-IN-2 is an inhibitor of PSMA with a Ki value of 1.07 nM. PSMA-IN-2 displays favorable in vivo NIR imaging (λEM = 1088 nm, λex = 808 nm), and can be used for NIRII image-guided tumor resection surgery in PSMA-positive tumor-bearing mice .
Referencia número: HY-P2251
No. CAS: 2022956-62-1
Target:
Áreas de investigación:
Referencia número: HY-P1142
No. CAS: 195262-56-7
Referencia número: HY-P1142A
Referencia número: HY-P1142S
Target:
Áreas de investigación:
Referencia número: HY-P1142S1
Target:
Áreas de investigación:
Referencia número: HY-120396
No. CAS: 141318-62-9
Target:
Áreas de investigación:
LY 293284 is a potent and selective 5-HT1A receptor agonist. LY 293284 results in a significant drop in core temperature and consumes more food in cholestasis rat induced by bile duct resection .
Referencia número: HY-D2285
No. CAS: 2956672-93-6
Synonyms: Xylene blue free acid; C.I. Acid blue 1 free acid
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
