5 Results for "

severe acute pancreatitis

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "severe acute pancreatitis" in MCE Product Catalog:

1
Chrysin-7-O-glucuronide
Chrysin-7-O-glucuronide
0 Images
1 Cited Publications
Cat. No.: HY-N2376
CAS No.: 35775-49-6
Category:  

Flavones Plants Bignoniaceae Extract Oroxylum indicum (Linn.) Bentham ex Kurz Flavonoids Monophenols Other Diseases Phenols Disease Research Fields Medicago truncatula Gaertn. Labiatae Extract

Target:  

Glycosidase Amylases NF-κB

Chrysin-7-O-glucuronide is a flavonoid found in Scutellaria baicalensis. Chrysin-7-O-glucuronide inhibits α-glucosidase and α-amylase with IC50 values of 612.13 and 980.73 μg/mL. Chrysin-7-O-glucuronide suppresses NF-κB signaling activity. Chrysin-7-O-glucuronide scavenges free radicals, acts as a tight junction protector, and mitigates intestinal mucosal barrier injury. Chrysin-7-O-glucuronide can be used for the research of type 2 diabetes and severe acute pancreatitis-induced intestinal mucosal barrier injury .
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1
Piperlonguminine
Piperlonguminine
0 Images
1 Cited Publications
Cat. No.: HY-126562
CAS No.: 5950-12-9
Purity:  99.31%
Category:  

Cardiovascular Disease Neurological Disease Plants Solanaceae Extract Infection Alkaloids Capsicum annuum L. Other Alkaloids Disease Research Fields Inflammation/Immunology

Target:  

Parasite p38 MAPK NF-κB Cytochrome P450

Piperlonguminine is a cytochrome P450 (CYP450) inhibitor. Piperlonguminine also inhibits the growth of epimastigotes and intracellular amastigotes of Trypanosoma cruzi, with IC50 values of 53.8 and 33.9 μM, respectively . Piperlonguminine regulates HMGB1/TLR4-NF-κB/MAPK-related inflammatory responses, endothelial protein C receptor (EPCR) shedding, melanogenesis, glycolipid metabolism, ischemic brain injury and tumor growth. Piperlonguminine can be used in research on hyperlipidemia, sepsis, Chagas disease, ischemic stroke, sarcoma and severe acute pancreatitis-associated lung injury .
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CYP2E1-IN-1
CYP2E1-IN-1
0 Images
Cat. No.: HY-W072025
CAS No.: 38205-55-9
Target:  

Cytochrome P450 Keap1-Nrf2 Heme Oxygenase (HO) Reactive Oxygen Species (ROS)

Research Areas:  

Inflammation/Immunology

CYP2E1-IN-1 (Compound 10) is an orally active cytochrome P450 2E1 (CYP2E1) inhibitor with a Kd of 7.02 μM, an IC50 of 1.64 μM, and a Ki of 0.897 μM. CYP2E1-IN-1 activates the Nrf2/HO-1 signaling pathway and inhibits ROS production, thereby alleviating pancreatic injury. CYP2E1-IN-1 has significant anti-inflammatory and antioxidant activities and can effectively reduce inflammation and oxidative stress in severe acute pancreatitis (SAP). CYP2E1-IN-1 can be used in the study of SAP and other inflammatory-related diseases .
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Piperlonguminine (Standard)
Piperlonguminine (Standard)
0 Images
Cat. No.: HY-126562R
CAS No.: 5950-12-9
Category:  

Alkaloids Capsicum annuum L. Other Alkaloids Plants Solanaceae Extract

Target:  

Reference Standards Parasite p38 MAPK NF-κB Cytochrome P450

Piperlonguminine (Standard) is the analytical standard of Piperlonguminine (HY-126562). This product is intended for research and analytical applications. Piperlonguminine is a cytochrome P450 (CYP450) inhibitor. Piperlonguminine also inhibits the growth of epimastigotes and intracellular amastigotes of Trypanosoma cruzi, with IC50 values of 53.8 and 33.9 μM, respectively . Piperlonguminine regulates HMGB1/TLR4-NF-κB/MAPK-related inflammatory responses, endothelial protein C receptor (EPCR) shedding, melanogenesis, glycolipid metabolism, ischemic brain injury and tumor growth. Piperlonguminine can be used in research on hyperlipidemia, sepsis, Chagas disease, ischemic stroke, sarcoma and severe acute pancreatitis-associated lung injury .
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Chrysin-7-O-glucuronide (Standard)
Chrysin-7-O-glucuronide (Standard)
0 Images
Cat. No.: HY-N2376R
CAS No.: 35775-49-6
Category:  

Flavonoids Monophenols Flavones Phenols Plants Bignoniaceae Extract Oroxylum indicum (Linn.) Bentham ex Kurz Medicago truncatula Gaertn. Labiatae Extract

Target:  

Reference Standards Glycosidase Amylases NF-κB

Chrysin-7-O-glucuronide (Standard) is the analytical standard of Chrysin-7-O-glucuronide (Hy-N2376). This product is intended for research and analytical applications. Chrysin-7-O-glucuronide is a flavonoid found in Scutellaria baicalensis. Chrysin-7-O-glucuronide inhibits α-glucosidase and α-amylase with IC50 values of 612.13 and 980.73 μg/mL. Chrysin-7-O-glucuronide suppresses NF-κB signaling activity. Chrysin-7-O-glucuronide scavenges free radicals, acts as a tight junction protector, and mitigates intestinal mucosal barrier injury. Chrysin-7-O-glucuronide can be used for the research of type 2 diabetes and severe acute pancreatitis-induced intestinal mucosal barrier injury .
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