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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
specific endonuclease
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "specific endonuclease" in MCE Product Catalog:
53
53 Publications Verification
STF-083010 is a specific IRE1α inhibitor. STF-083010 inhibits Ire1 endonuclease activity, without affecting its kinase activity, after endoplasmic reticulum stress.
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2 Cited Publications
Cat. No.: HY-W014622
CAS No.: 6960-45-8
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CRT0044876 is a potent and selective apurinic/apyrimidinic endonuclease 1 (APE1) inhibitor (IC50=~3 μM). CRT0044876 inhibits the AP endonuclease, 3′-phosphodiesterase and 3′-phosphatase activities of APE1, and is a specific inhibitor of the exonuclease III family of enzymes to which APE1 belongs. CRT0044876 potentiates the cytotoxicity of several DNA base-targeting compounds .
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1 Cited Publications
Cat. No.: HY-P2963
CAS No.: 54576-84-0
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Nuclease P1 is a single-stranded specific endonuclease, it hydrolyzes nucleic acids into 5'-mononucleotides and cleaves the single-stranded region of a double-stranded nucleic acid. Nuclease P1 is one of the most well-known single stranded specific nucleases in the field of molecular biology, it is widely used in the pharmaceutical and food industries . Nuclease P1 can be obtained by fermentation of Penicillium citrinum: through extraction process, ultrafiltration concentration, drying and purification, etc.
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Cat. No.: HY-P2773
CAS No.: 37288-25-8
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Nuclease S1, Aspergillus oryzae is a specific endonuclease that degrades single stranded DNA (ssDNA) and RNA. Nuclease S1 can also remove protruding single-strand ends from double-stranded DNA .
Cat. No.: HY-139678
CAS No.: 2839142-69-5
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SC13 is an orally active, selective Flap structure-specific endonuclease 1 (FEN1) inhibitor and mu opioid receptor (MOR) activator. SC13 impairs DNA damage repair and induces apoptosis in cancer cells. SC13 activates cGAS-STING signaling, increases chemokine secretion, and promotes CAR-T cell infiltration at solid tumour sites. SC13 can be used for the research of solid tumours and pain .
Cat. No.: HY-E70381
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dsDNase is a highly specific double-strand DNA (dsDNA) endonuclease that quickly and efficiently removes contaminating DNA from PCR master mixes .
Cat. No.: HY-E70603
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T4 endonuclease VII displays broad substrate specificity and can bind and cleave single-base mismatches in a DNA duplex as well as three-way and four-way branched DNA structures .
Cat. No.: HY-P700010
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuFlap endonuclease 1/FEN-1; Flap endonuclease 1; FEN-1; DNase IV; Flap Structure-specific endonuclease 1; Maturation Factor 1; MF1; hFEN-1; FEN1; RAD2
Cat. No.: HY-P86821
Synonyms: Cleavage and polyadenylation specific factor 3 73kDa antibody; Cleavage and polyadenylation specificity factor 73 kDa subunit antibody; Cleavage and polyadenylation specificity factor subunit 3 antibody; CPSF 73 antibody; CPSF 73 kDa subunit antibody; CPSF antibody; CPSF-73 antibody; cpsf3 antibody; CPSF3_HUMAN antibody; CPSF73 antibody; Cleavage and polyadenylation specific factor 3 73kDa antibody; Cleavage and polyadenylation specificity factor 73 kDa subunit antibody; Cleavage and polyadenylation specificity factor subunit 3 antibody; CPSF 73 antibody; CPSF 73 kDa subunit antibody; CPSF antibody; CPSF-73 antibody; cpsf3 antibody; CPSF3_HUMAN antibody; CPSF73 antibody; mRNA 3''-end-processing endonuclease CPSF-73 antibody; YSH1 antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
