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Results for "

steviol

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aquaporin (2) Biochemical Assay Reagents (1) CFTR (2) Chloride Channel (2) DNA/RNA Synthesis (1) Drug Derivative (3) Drug Intermediate (1) Endogenous Metabolite (2) Fatty Acid Synthase (FASN) (2) GLUT (1) Glycosidase (2) HMG-CoA Reductase (HMGCR) (2) Interleukin Related (2) LDLR (2) Reactive Oxygen Species (ROS) (2) Reference Standards (5) Topoisomerase (2)
By Research Areas:	Cancer (2) Cardiovascular Disease (2) Metabolic Disease (5)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0466

Rebaudioside A	Glycosidase HMG-CoA Reductase (HMGCR) Fatty Acid Synthase (FASN) LDLR	Others
Rebaudioside A is an orally effective steviol glycoside with high sweetness. Rebaudioside A acts as an inhibitor of α-glucosidase with an IC₅₀ value of 35.01 μg/mL. Rebaudioside A increases the ATP/ADP ratio in β cells in a glucose-dependent manner, thereby inhibiting KATP channels, leading to membrane depolarization, calcium influx, and ultimately stimulating insulin secretion. Rebaudioside A activates the SREBP signaling pathway by inhibiting HMGCR, the rate-limiting enzyme in cholesterol synthesis, resulting in increased expression of LDLR on the cell surface, thus promoting the uptake of LDL-C in the blood. Rebaudioside A can be used for studies on blood glucose and lipid regulation as well as anti-obesity .

HY-N6888

Rebaudioside E	Others	Others
Rebaudioside E is a steviol glycoside isolated from Stevia rebaudiana leaves .

HY-N2057

*Steviol*	Aquaporin CFTR Chloride Channel	Metabolic Disease
Steviol is the main metabolite of steviol glycosides and an inhibitor of AQP2/CFTR. Steviol slows down the growth of renal cysts by inhibiting the activity of CFTR, reducing the expression of AQP2, and promoting the degradation of AQP2 and CFTR. Steviol can be used in the research of polycystic kidney disease .

HY-N0872

Isosteviol (-)-Isosteviol; iso-steviol	Interleukin Related DNA/RNA Synthesis Reactive Oxygen Species (ROS) Topoisomerase	Cardiovascular Disease Cancer
Isosteviol ((-)-Isosteviol) is a derivative of Stevioside through acid catalyzed hydrolysis of Stevioside. Isosteviol inhibits DNA polymerase and DNA topoisomerase and has antibacterial, anticancer and anti-tuberculosis effects .

HY-N6889

Rebaudioside I	Drug Derivative	Others
Rebaudioside I is a natural non-caloric high-potency sweetener belonging to the steviol glycoside family, which can be isolated from Stevia rebaudiana Morita .

HY-N6808

Rebaudioside B	Others	Others
Rebaudioside B is the minor constituent isolated from the leaves of Stevia rebaudiana Bertoni. Rebaudioside B tastes about 150 times sweeter than sucrose. Rebaudioside B can hydrolysis to steviol .

HY-N6887

Rebaudioside F	Others	Others
Rebaudioside F is a steviol glycoside isolated from Stevia rebaudiana leaves. is a new natural sweet ingredient .

HY-N8009

Rebaudioside O	Biochemical Assay Reagents	Others
Rebaudioside O is a heptapyranosyl diterpene glycoside that occurs in the leaves of Stevia rebaudiana Bertoni. Rebaudioside O serves as a sweetener .

HY-125062

Steviolmonoside Glucosilsteviol	GLUT	Metabolic Disease
Steviolmonoside (Glucosilsteviol) is a structural analogue of steviol. Steviolmonoside decreases glucose production and inhibits oxygen uptake in rat renal cortical tubules .

HY-N6832

Rebaudioside N	Others	Others
Rebaudioside N is a minor steviol glycoside isolated from the leaves of Stevia rebaudiana Bertoni .

HY-N6918

Steviol-19-O-glucoside	Others	Metabolic Disease
Steviol-19-O-glucoside is a metabolite of steviol in the steviol glycosides biosynthesis pathway in Stevia rebuadiana .

HY-N6832R

Rebaudioside N (Standard)	Reference Standards Others	Others
Rebaudioside N (Standard) is the analytical standard of Rebaudioside N. This product is intended for research and analytical applications. Rebaudioside N is a minor steviol glycoside isolated from the leaves of Stevia rebaudiana Bertoni .

HY-N2057R

Steviol (Standard)	Reference Standards Aquaporin CFTR Chloride Channel	Metabolic Disease
Steviol (Standard) is the analytical standard of Steviol (HY-N2057). This product is intended for research and analytical applications. Steviol is the main metabolite of steviol glycosides and an inhibitor of AQP2/CFTR. Steviol slows down the growth of renal cysts by inhibiting the activity of CFTR, reducing the expression of AQP2, and promoting the degradation of AQP2 and CFTR. Steviol can be used in the research of polycystic kidney disease .

HY-N5123

α-L-Rhamnose	Endogenous Metabolite	Metabolic Disease
α-L-Rhamnose is a neutral sugar present in plants, animals, viruses and bacteria. α-L-Rhamnose is a ligand for α-L-rhamnose-recognizing lectin sites, trigger intracellular signaling pathways. α-L-Rhamnose induces rhaE and rhaA expression as a specific carbon source in Aspergillus nidulans, while glucose inhibits its cellular uptake. α-L-Rhamnose induces rapid and transient increases in intracellular free Ca ²⁺ concentration in normal human dermal fibroblasts .

HY-N6888R

Rebaudioside E (Standard)	Reference Standards Drug Intermediate	Others
Rebaudioside E (Standard) is the analytical standard of Rebaudioside E. This product is intended for research and analytical applications. Rebaudioside E is a steviol glycoside and also a high-intensity sweetener. The sweetness of Rebaudioside E is 150-300 times that of sucrose. Rebaudioside E serves as a precursor for the biosynthesis of Rebaudioside D (HY-N0468) and Rebaudioside M (HY-N6833).

HY-N0466R

Rebaudioside A (Standard)	Reference Standards Glycosidase HMG-CoA Reductase (HMGCR) Fatty Acid Synthase (FASN) LDLR	Others
Rebaudioside A (Standard) is the analytical standard of Rebaudioside A. This product is intended for research and analytical applications. Rebaudioside A is an orally effective steviol glycoside with high sweetness. Rebaudioside A acts as an inhibitor of α-glucosidase with an IC₅₀ value of 35.01 μg/mL. Rebaudioside A increases the ATP/ADP ratio in β cells in a glucose-dependent manner, thereby inhibiting KATP channels, leading to membrane depolarization, calcium influx, and ultimately stimulating insulin secretion. Rebaudioside A activates the SREBP signaling pathway by inhibiting HMGCR, the rate-limiting enzyme in cholesterol synthesis, resulting in increased expression of LDLR on the cell surface, thus promoting the uptake of LDL-C in the blood. Rebaudioside A can be used for studies on blood glucose and lipid regulation as well as anti-obesity.

HY-N18338

Steviol-15-ene	Drug Derivative	Others
Steviol-15-ene is a Δ ¹⁵-double bond isomer of steviol, a tetracyclic diterpenoid. Steviol-15-ene undergoes 7β-hydroxylation by Gibberella fujikuroi to form methyl ent-7α,13-dihydroxykaur-15-en-19-oate .

HY-N0872R

Isosteviol (Standard) (-)-Isosteviol (Standard); iso-steviol (Standard)	Interleukin Related Reference Standards Reactive Oxygen Species (ROS) Topoisomerase	Cardiovascular Disease Cancer
Isosteviol (Standard) is the analytical standard of Isosteviol. This product is intended for research and analytical applications. Isosteviol ((-)-Isosteviol) is a derivative of Stevioside through acid catalyzed hydrolysis of Stevioside. Isosteviol inhibits DNA polymerase and DNA topoisomerase and has antibacterial, anticancer and anti-tuberculosis effects .

HY-N11064

Rebaudioside S	Others	Others
Rebaudioside S is a minor steviol glycoside that can be isolated from the leaves of Stevia rebaudiana .

HY-N18366

Dulcoside C	Drug Derivative	Others
Dulcoside C is a rhamnose-containing steviol glycoside found in Stevia rebaudiana leaves.Dulcoside C exhibits significantly lower sweetness compared to Rebaudioside A (HY-N0466) .

HY-N18729

Stevia rebaudiana extract	Others	Others
Stevia rebaudiana extract is derived from the leaves of the stevia plant. Its active ingredients are steviol glycosides, primarily steviol glycosides and rebaudioside A, which give stevia its extremely high sweetness. Stevia rebaudiana extract is used as a natural, zero-calorie sweetener in various foods and beverages, serving as an alternative to sucrose and artificial sweeteners.

HY-171664

ent-Copalyl diphosphate ent-CPP	Endogenous Metabolite	Others
ent-Copalyl diphosphate (ent-CPP) is a terpenoid precursor and metabolite involved in plant biosynthetic pathways. ent-Copalyl diphosphate participates in metabolism of natural products including phytoalexins in rice and maize, and steviol glycoside in Stevia rebaudiana .

Rebaudioside A	Structural Classification Classification of Application Fields Plants Compositae Endogenous metabolite Sweeteners Food Research Trifolium hybridum L. Terpenoids Other Diseases Diterpenoids Disease Research Fields Source Classification	Glycosidase HMG-CoA Reductase (HMGCR) Fatty Acid Synthase (FASN) LDLR
Rebaudioside A is an orally effective steviol glycoside with high sweetness. Rebaudioside A acts as an inhibitor of α-glucosidase with an IC₅₀ value of 35.01 μg/mL. Rebaudioside A increases the ATP/ADP ratio in β cells in a glucose-dependent manner, thereby inhibiting KATP channels, leading to membrane depolarization, calcium influx, and ultimately stimulating insulin secretion. Rebaudioside A activates the SREBP signaling pathway by inhibiting HMGCR, the rate-limiting enzyme in cholesterol synthesis, resulting in increased expression of LDLR on the cell surface, thus promoting the uptake of LDL-C in the blood. Rebaudioside A can be used for studies on blood glucose and lipid regulation as well as anti-obesity .

Rebaudioside E	other families Classification of Application Fields Terpenoids Other Diseases Diterpenoids Plants Disease Research Fields Source Classification	Others
Rebaudioside E is a steviol glycoside isolated from Stevia rebaudiana leaves .

*Steviol*	Other Terpenoids Structural Classification other families Classification of Application Fields Terpenoids Metabolic Disease Plants Disease Research Fields Sweeteners Source Classification Food Research	Aquaporin CFTR Chloride Channel
Steviol is the main metabolite of steviol glycosides and an inhibitor of AQP2/CFTR. Steviol slows down the growth of renal cysts by inhibiting the activity of CFTR, reducing the expression of AQP2, and promoting the degradation of AQP2 and CFTR. Steviol can be used in the research of polycystic kidney disease .

Isosteviol (-)-Isosteviol; iso-steviol	Structural Classification other families Classification of Application Fields Terpenoids Diterpenoids Plants Disease Research Fields Source Classification Cancer	Interleukin Related DNA/RNA Synthesis Reactive Oxygen Species (ROS) Topoisomerase
Isosteviol ((-)-Isosteviol) is a derivative of Stevioside through acid catalyzed hydrolysis of Stevioside. Isosteviol inhibits DNA polymerase and DNA topoisomerase and has antibacterial, anticancer and anti-tuberculosis effects .

Rebaudioside I	Structural Classification other families Classification of Application Fields Terpenoids Other Diseases Diterpenoids Plants Disease Research Fields Sweeteners Source Classification Food Research	Drug Derivative
Rebaudioside I is a natural non-caloric high-potency sweetener belonging to the steviol glycoside family, which can be isolated from Stevia rebaudiana Morita .

Rebaudioside B	Trifolium hybridum L. other families Classification of Application Fields Terpenoids Other Diseases Diterpenoids Plants Compositae Disease Research Fields Source Classification	Others
Rebaudioside B is the minor constituent isolated from the leaves of Stevia rebaudiana Bertoni. Rebaudioside B tastes about 150 times sweeter than sucrose. Rebaudioside B can hydrolysis to steviol .

Rebaudioside F	other families Classification of Application Fields Terpenoids Other Diseases Diterpenoids Plants Disease Research Fields Source Classification	Others
Rebaudioside F is a steviol glycoside isolated from Stevia rebaudiana leaves. is a new natural sweet ingredient .

Rebaudioside O	Structural Classification Terpenoids Cassia Diterpenoids Plants Compositae Source Classification	Biochemical Assay Reagents
Rebaudioside O is a heptapyranosyl diterpene glycoside that occurs in the leaves of Stevia rebaudiana Bertoni. Rebaudioside O serves as a sweetener .

Rebaudioside N	other families Classification of Application Fields Terpenoids Other Diseases Diterpenoids Plants Disease Research Fields Source Classification	Others
Rebaudioside N is a minor steviol glycoside isolated from the leaves of Stevia rebaudiana Bertoni .

Steviol-19-O-glucoside	other families Classification of Application Fields Terpenoids Metabolic Disease Diterpenoids Plants Disease Research Fields Source Classification	Others
Steviol-19-O-glucoside is a metabolite of steviol in the steviol glycosides biosynthesis pathway in Stevia rebuadiana .

Rebaudioside N (Standard)	Structural Classification other families Terpenoids Diterpenoids Plants Source Classification	Reference Standards Others
Rebaudioside N (Standard) is the analytical standard of Rebaudioside N. This product is intended for research and analytical applications. Rebaudioside N is a minor steviol glycoside isolated from the leaves of Stevia rebaudiana Bertoni .

Steviol (Standard)	Other Terpenoids Structural Classification other families Terpenoids Plants Source Classification	Reference Standards Aquaporin CFTR Chloride Channel
Steviol (Standard) is the analytical standard of Steviol (HY-N2057). This product is intended for research and analytical applications. Steviol is the main metabolite of steviol glycosides and an inhibitor of AQP2/CFTR. Steviol slows down the growth of renal cysts by inhibiting the activity of CFTR, reducing the expression of AQP2, and promoting the degradation of AQP2 and CFTR. Steviol can be used in the research of polycystic kidney disease .

α-L-Rhamnose	Structural Classification Microorganisms Classification of Application Fields Other Diseases Disease Research Fields Saccharides Monosaccharides Source Classification	Endogenous Metabolite
α-L-Rhamnose is a neutral sugar present in plants, animals, viruses and bacteria. α-L-Rhamnose is a ligand for α-L-rhamnose-recognizing lectin sites, trigger intracellular signaling pathways. α-L-Rhamnose induces rhaE and rhaA expression as a specific carbon source in Aspergillus nidulans, while glucose inhibits its cellular uptake. α-L-Rhamnose induces rapid and transient increases in intracellular free Ca ²⁺ concentration in normal human dermal fibroblasts .

Rebaudioside E (Standard)	Structural Classification other families Terpenoids Diterpenoids Plants Source Classification	Reference Standards Drug Intermediate
Rebaudioside E (Standard) is the analytical standard of Rebaudioside E. This product is intended for research and analytical applications. Rebaudioside E is a steviol glycoside and also a high-intensity sweetener. The sweetness of Rebaudioside E is 150-300 times that of sucrose. Rebaudioside E serves as a precursor for the biosynthesis of Rebaudioside D (HY-N0468) and Rebaudioside M (HY-N6833).

Rebaudioside A (Standard)	Structural Classification Trifolium hybridum L. Terpenoids Diterpenoids Plants Compositae Endogenous metabolite Source Classification	Reference Standards Glycosidase HMG-CoA Reductase (HMGCR) Fatty Acid Synthase (FASN) LDLR
Rebaudioside A (Standard) is the analytical standard of Rebaudioside A. This product is intended for research and analytical applications. Rebaudioside A is an orally effective steviol glycoside with high sweetness. Rebaudioside A acts as an inhibitor of α-glucosidase with an IC₅₀ value of 35.01 μg/mL. Rebaudioside A increases the ATP/ADP ratio in β cells in a glucose-dependent manner, thereby inhibiting KATP channels, leading to membrane depolarization, calcium influx, and ultimately stimulating insulin secretion. Rebaudioside A activates the SREBP signaling pathway by inhibiting HMGCR, the rate-limiting enzyme in cholesterol synthesis, resulting in increased expression of LDLR on the cell surface, thus promoting the uptake of LDL-C in the blood. Rebaudioside A can be used for studies on blood glucose and lipid regulation as well as anti-obesity.

Steviol-15-ene	Structural Classification Microorganisms Terpenoids Diterpenoids Source Classification	Drug Derivative
Steviol-15-ene is a Δ ¹⁵-double bond isomer of steviol, a tetracyclic diterpenoid. Steviol-15-ene undergoes 7β-hydroxylation by Gibberella fujikuroi to form methyl ent-7α,13-dihydroxykaur-15-en-19-oate .

Isosteviol (Standard) (-)-Isosteviol (Standard); iso-steviol (Standard)	Structural Classification other families Terpenoids Diterpenoids Plants Source Classification	Interleukin Related Reference Standards Reactive Oxygen Species (ROS) Topoisomerase
Isosteviol (Standard) is the analytical standard of Isosteviol. This product is intended for research and analytical applications. Isosteviol ((-)-Isosteviol) is a derivative of Stevioside through acid catalyzed hydrolysis of Stevioside. Isosteviol inhibits DNA polymerase and DNA topoisomerase and has antibacterial, anticancer and anti-tuberculosis effects .

Rebaudioside S	Terpenoids Cassia Diterpenoids Plants Compositae Source Classification	Others
Rebaudioside S is a minor steviol glycoside that can be isolated from the leaves of Stevia rebaudiana .

Dulcoside C	Structural Classification Terpenoids Cassia Diterpenoids Plants Compositae Source Classification	Drug Derivative
Dulcoside C is a rhamnose-containing steviol glycoside found in Stevia rebaudiana leaves.Dulcoside C exhibits significantly lower sweetness compared to Rebaudioside A (HY-N0466) .

Stevia rebaudiana extract	Structural Classification Extract	Others
Stevia rebaudiana extract is derived from the leaves of the stevia plant. Its active ingredients are steviol glycosides, primarily steviol glycosides and rebaudioside A, which give stevia its extremely high sweetness. Stevia rebaudiana extract is used as a natural, zero-calorie sweetener in various foods and beverages, serving as an alternative to sucrose and artificial sweeteners.

ent-Copalyl diphosphate ent-CPP	Structural Classification Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Source Classification	Endogenous Metabolite
ent-Copalyl diphosphate (ent-CPP) is a terpenoid precursor and metabolite involved in plant biosynthetic pathways. ent-Copalyl diphosphate participates in metabolism of natural products including phytoalexins in rice and maize, and steviol glycoside in Stevia rebaudiana .

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Inhibitors & Agonists

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