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strain-promoted alkyne-azide cycloaddition

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GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-42973
    DBCO-NHS ester
    5+ Cited Publications

    ADC Linker Cancer
    DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-NHS ester
  • HY-140272
    DBCO-PEG4-NHS ester
    4 Publications Verification

    PROTAC Linkers Cancer
    DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG4-NHS ester
  • HY-130809
    DBCO-PEG4-Biotin
    4 Publications Verification

    Biochemical Assay Reagents Cancer
    DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction . DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG4-Biotin
  • HY-W000423
    DBCO-amine
    1 Publications Verification

    Biochemical Assay Reagents Cancer
    DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-amine is used in the synthesis of antibody-drug conjugates (ADCs) .
    DBCO-amine
  • HY-116270

    ADC Linker Cancer
    DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-Maleimide
  • HY-140947
    TAMRA-Azide-PEG-biotin
    1 Publications Verification

    Fluorescent Dye Others
    TAMRA-Azide-PEG-biotin is a dye derivative of TAMRA (HY-135640). TAMRA-Azide-PEG-biotin contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    TAMRA-Azide-PEG-biotin
  • HY-126851

    ADC Linker Cancer
    Fluorescein-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Fluorescein-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    Fluorescein-DBCO
  • HY-123687

    ADC Linker Cancer
    DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-Sulfo-NHS ester sodium
  • HY-43581

    PROTAC Linkers Cancer
    endo-BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-O-PNB is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    endo-BCN-O-PNB
  • HY-123916

    PROTAC Linkers Cancer
    DBCO-Biotin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-Biotin
  • HY-130937

    ADC Linker Cancer
    DBCO-Val-Cit-PABC-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Val-Cit-PABC-PNP is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-Val-Cit-PABC-PNP
  • HY-130810

    ADC Linker Cancer
    DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-Link-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-Sulfo-Link-biotin
  • HY-101532

    β-CDN3; 6A-deoxy-6A-azido-β-cyclodextrin

    Biochemical Assay Reagents Others
    6A-Azido-6A-deoxy-β-cyclodextrin (β-CDN3) is a site-specifically modified β-cyclodextrin with a single azido group replacing the hydroxyl group at the C6 position. 6A-Azido-6A-deoxy-β-cyclodextrin forms a host-guest inclusion complex with Dexamethasone (HY-14648), localizing the drug within its hydrophobic cavity, which restricts the rotational mobility of the drug and places Dexamethasone in a less polar environment. 6A-Azido-6A-deoxy-β-cyclodextrin acts as a coupling agent to graft β-cyclodextrin onto thermosensitive nanogels via strain-promoted alkyne-azide cycloaddition (SPAAC). 6A-Azido-6A-deoxy-β-cyclodextrin also serves as a click chemistry reagent. It contains an azide group and undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules bearing an alkyne group. It also undergoes strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
    6A-Azido-6A-deoxy-β-cyclodextrin
  • HY-157054

    Biochemical Assay Reagents Others
    Endo-BCN-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. Endo-BCN-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    endo-BCN-L-Lysine
  • HY-148194

    Drug-Linker Conjugates for ADC Cancer
    SC239 is a cleavable 2-aminophenyl hemiasterlin agent-linker. SC239 can be as the agent-linker for ADC . SC239 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    SC239
  • HY-133413

    ADC Linker Cancer
    DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-CONH-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-CONH-S-S-NHS ester
  • HY-W096149

    Biochemical Assay Reagents Others
    exo-BCN-NHS carbonate carbonate contains BCN group. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    exo-BCN-NHS carbonate
  • HY-W754588

    PROTAC Linkers Others
    exo-BCN-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. exo-BCN-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    exo-BCN-L-Lysine
  • HY-133412

    ADC Linker Cancer
    DBCO-NHCO-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-NHCO-S-S-NHS ester
  • HY-127056
    Sulfo DBCO-amine
    1 Publications Verification

    PROTAC Linkers Cancer
    Sulfo DBCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Sulfo DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    Sulfo DBCO-amine
  • HY-133406

    PROTAC Linkers Cancer
    exo BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . exo BCN-O-PNB is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    exo BCN-O-PNB
  • HY-147325

    ADC Linker Others
    bisSP1 is an antibody agent conjugates linker . bisSP1 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    bisSP1
  • HY-140318

    PROTAC Linkers Cancer
    DBCO-mPEG (MW 2kDa) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-mPEG (MW 2kDa) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-mPEG (MW 2kDa)
  • HY-W250928B

    PROTAC Linkers Cancer
    Biotin-PEG1000-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Biotin-PEG1000-azide
  • HY-141293

    PROTAC Linkers Cancer
    Oleic-DBCO is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Oleic-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    Oleic-DBCO
  • HY-135973

    ADC Linker Cancer
    BCN-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-SS-NHS is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-SS-NHS
  • HY-140319

    PROTAC Linkers Cancer
    DBCO-mPEG (MW 5kDa) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-mPEG (MW 5kDa) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-mPEG (MW 5kDa)
  • HY-D2177

    Fluorescent Dye Others
    AF 555 azide is a fluorescent dye and is the azide of AF 555. It contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 555/565 nm) .
    AF 555 azide
  • HY-151717

    Spermine(HHHN3) trihydrochloride

    ADC Linker Others
    N1-Azido-spermine [Spermine(HHHN3)] trihydrochloride is a click chemistry agent containing azide. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    N1-Azido-spermine trihydrochloride
  • HY-140955

    PROTAC Linkers Cancer
    DSPE-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DSPE-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DSPE-PEG4-DBCO
  • HY-D2617

    Fluorescent Dye Others
    ICG PEG5000 DBCO is a fluorescent probe containing Indocyanine green (ICG) (HY-D0711) dye. ICG PEG5000 DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups (Ex/Em=785/813 nm).
    ICG PEG5000 DBCO
  • HY-13025
    HIV-1 integrase inhibitor
    1 Publications Verification

    HIV HIV Integrase Infection
    HIV-1 integrase inhibitor is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    HIV-1 integrase inhibitor
  • HY-140322

    PROTAC Linkers Cancer
    DBCO-Mpeg30000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-Mpeg30000 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-Mpeg30000
  • HY-140267

    PROTAC Linkers Cancer
    DBCO-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG5-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG5-acid
  • HY-130936

    ADC Linker Cancer
    DBCO-Val-Cit-PABC-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Val-Cit-PABC-OH is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-Val-Cit-PABC-OH
  • HY-140305

    PROTAC Linkers Cancer
    DBCO-PEG13-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG13-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG13-DBCO
  • HY-133009

    PROTAC Linkers Cancer
    BCN-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. BCN-PEG4-acid contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-PEG4-acid
  • HY-138506

    ADC Linker Cancer
    DBCO-S-S-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-S-S-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-S-S-acid
  • HY-130935

    ADC Linker Cancer
    DBCO-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Val-Cit-OH is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-Val-Cit-OH
  • HY-140265

    PROTAC Linkers Cancer
    DBCO-PEG1-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG1-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG1-acid
  • HY-100825

    Biochemical Assay Reagents Others
    OABK hydrochloride is a small-molecule switch that can be used to control protein activity. OABK (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    OABK hydrochloride
  • HY-W250928E

    PROTAC Linkers Cancer
    Biotin-PEG5000-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Biotin-PEG5000-azide
  • HY-151638

    ADC Linker Others
    FMOC-3-azido-D-alanine is a click chemistry reagent containing an azide group . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    FMOC-3-azido-D-alanine
  • HY-151674

    ADC Linker Others
    N3-L-Cys(Trt)-OH (CHA) is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    N3-L-Cys(Trt)-OH (CHA)
  • HY-140302

    PROTAC Linkers Cancer
    DBCO-PEG5-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG5-DBCO
  • HY-140283

    PROTAC Linkers Cancer
    DBCO-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG2-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG2-amine
  • HY-D2112

    Fluorescent Dye Others
    TAMRA-PEG7-N3 is a TAMRA (HY-135640) dye derivative containing 7 PEG units. TAMRA-PEG7-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    TAMRA-PEG7-N3
  • HY-D2111

    Fluorescent Dye Others
    TAMRA-PEG2-N3 is a TAMRA (HY-135640) dye derivative containing 4 PEG units. TAMRA-PEG2-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    TAMRA-PEG2-N3
  • HY-181228

    Biochemical Assay Reagents Others
    DBCO-PEG10-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 10 PEGs. DBCO-PEG10-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction. DBCO-PEG10-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
    DBCO-PEG10-Biotin
  • HY-157052

    PROTAC Linkers Others
    exo-BCN-Fmoc-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. exo-BCN-Fmoc-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    exo-BCN-Fmoc-L-Lysine

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