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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
stromelysin
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "stromelysin" in MCE Product Catalog:
1
1 Cited Publications
NNGH is a stromelysin-1 (MMP-3) inhibitor. MMP-3 is both a direct transcriptional target and a necessary contributor of the Wnt/β-catenin signaling pathway. Matrix metalloproteinases (MMPs) play a well-defined role in later stages of tumor progression .
Cat. No.: HY-P3699
CAS No.: 202273-56-1
Target:
Research Areas:
Cat. No.: HY-18694
CAS No.: 169799-04-6
Target:
Research Areas:
CGS 27023A is a non-peptidic and orally active MMP inhibitor with the Ki values of 43, 33, 20 and 8 nM for MMP-3, MMP-1, MMP-2 amd MMP-9, respectively. CGS 27023A prevents cartilage degradation in stromelysin-induced rabbit cartilage degradation model. CGS 27023A can be used for study of arthritis .
Cat. No.: HY-P3699A
Target:
Research Areas:
TNO003 TFA is a selective fluorogenic substrate for stromelysin-1 (MMP-3). TNO003 TFA has higher selectivity for MMP-3 than MMP-1, MMP-2, MMP-7, MMP-8, MMP-9 and MMP-13. TNO003 TFA can be used for the determination of stromelysin activity (Ex/Em = 360/490 nm) .
Cat. No.: HY-P3202
CAS No.: 79955-99-0
Synonyms: MMP-3; stromelysin-1
Target:
Research Areas:
Matrix metalloproteinase 3 (MMP-3) is a member of the class of zinc-dependent proteases that can degrade the extracellular matrix (ECM). Matrix metalloproteinase 3 palys an important role in the neuronal apoptotic process as well as in neuroinflammation. Matrix metalloproteinase 3 can be used in the study of neurodegenerative diseases including Alzheimer’s disease (AD) and Parkinson’s disease (PD) .
Cat. No.: HY-P4937
CAS No.: 945414-97-1
Cat. No.: HY-N16446
CAS No.: 345295-46-7
Category:
Target:
Cat. No.: HY-18694A
CAS No.: 161314-70-1
Target:
Research Areas:
CGS 27023A free base is a non-peptidic and orally active MMP inhibitor with the Ki values of 43, 33, 20 and 8 nM for MMP-3, MMP-1, MMP-2 amd MMP-9, respectively. CGS 27023A free base prevents cartilage degradation in stromelysin-induced rabbit cartilage degradation model. CGS 27023A free base can be used for study of arthritis .
Cat. No.: HY-171776
CAS No.: 166245-54-1
OPB-3206 is a selective matrix metalloproteinase (MMP) inhibitor. OPB-3206 inhibits interstitial collagenase, gelatinase A (MMP-2), gelatinase B (MMP-9) and stromelysin with IC50 values of 7×10 -7 M, 5×10 -6 M, 5×10 -7 M and 2×10 -6 M, respectively. OPB-3206 reversibly binds to the zinc-binding region of MMPs, preventing the activation of MMP-9 and reducing extracellular matrix degradation to inhibit tumor lung metastasis. OPB-3206 is promising for research of lung metastasis of osteosarcoma .
Cat. No.: HY-P73297
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MMP3; SL-1; Prev. STMY1; Matrix Metalloproteinase 3; Prev. STMY; Proteoglycanase; Matrix Metalloproteinase 3 (stromelysin 1, Progelatinase); stromelysin 1; stromelysin-1; CHDS6; Transin-1; STR1; MMP-3; Matrix Metallopeptidase 3; Matrix Metalloproteinase-3
Species:
Human
Source:
E. coli
Cat. No.: HY-P70139
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MMP3; SL-1; Prev. STMY1; Matrix Metalloproteinase 3; Prev. STMY; Proteoglycanase; Matrix Metalloproteinase 3 (stromelysin 1, Progelatinase); stromelysin 1; stromelysin-1; CHDS6; Transin-1; STR1; MMP-3; Matrix Metallopeptidase 3; Matrix Metalloproteinase-3
Species:
Human
Source:
HEK293
Cat. No.: HY-P704541
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MMP10; MMP-10; Prev. STMY2; Matrix Metalloprotease 10; Matrix Metalloproteinase 10 (stromelysin 2); stromelysin 2; Matrix Metalloproteinase-10; Transin 2; stromelysin-2; Transin-2; Matrix Metallopeptidase 10; SL-2
Species:
Human
Source:
HEK293
Cat. No.: HY-N11418
CAS No.: 149064-34-6
Category:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
