CGS 27023A free base
CGS 27023A free base is a non-peptidic and orally active MMP inhibitor with the Ki values of 43, 33, 20 and 8 nM for MMP-3, MMP-1, MMP-2 amd MMP-9, respectively. CGS 27023A free base prevents cartilage degradation in stromelysin-induced rabbit cartilage degradation model. CGS 27023A free base can be used for study of arthritis.
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- CAS No.: 161314-70-1
- Formule: C18H23N3O5S
- Masse moléculaire:393.46
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
MMP-3 43 nM (Ki) |
MMP-1 33 nM (Ki) |
MMP-2 20 nM (Ki) |
MMP-9 8 nM (Ki) |
Chemical Information
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CAS No. 161314-70-1
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Masse moléculaire 393.46
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Formule C18H23N3O5S
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SMILES
CC(C)[C@@H](N(S(=O)(C1=CC=C(OC)C=C1)=O)CC2=CC=CN=C2)C(NO)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CGS 27023A free base Related Classifications
HY-18694A Related Classifications
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