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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
superoxide anion generation
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "superoxide anion generation" in MCE Product Catalog:
6
6 Cited Publications
Research Areas:
HCH6-1 is a potent and competitive dipeptide antagonist of Formyl peptide receptor 1 (FPR1). HCH6-1 inhibits chemotaxis, superoxide anion generation, and elastase release in human neutrophils specifically activated by fMLF (an FPR1 agonist). HCH6-1 has protective effects against acute lung injury (ALI) in vivo and can be used for the research of FPR1-involved inflammatory lung diseases .
Cat. No.: HY-W115721
CAS No.: 523-21-7
Synonyms: Sodium rhodizonate dibasic
Target:
Research Areas:
Neutrophil elastase inhibitor 5 is an inhibitor of human neutrophil elastase (HNE), proteinase 3 (PR3) and sirt2, with IC50 values of 4.91, 20.69 and 2.42 μM, respectively. Neutrophil elastase inhibitor 5 inhibits superoxide anion production and elastase release in human neutrophils. Neutrophil elastase inhibitor 5 can be used for the research of neutrophil inflammatory diseases .
Cat. No.: HY-N13250
Cat. No.: HY-N10450
CAS No.: 72755-19-2
Synonyms: 1-Ethoxycarbonyl-β-carboline
Target:
Cat. No.: HY-132132
CAS No.: 1234707-32-4
Target:
Research Areas:
Neutrophil elastase inhibitor 3 (compound 13), a benzoxazinone analog, shows effects on superoxide anion generation and exhibits as a neutrophil elastase (NE) inhibitor, with an IC50 of 80.8 nM for NE release .
Cat. No.: HY-N3388
CAS No.: 66056-30-2
Category:
Flavonoids Leguminosae Metabolic Disease Phenols Polyphenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Isoflavones
Target:
against carcinogenic mutagen, by preventing DNA damage. Licoisoflavone B can be used for the research of psoriasis, Lassa fever, inflammation and cancer .
Cat. No.: HY-156468
Target:
Research Areas:
Antioxidant agent-17 (compound 59) is a potent inhibitor of superoxide anion generation activity, with an IC50 of 9.06 nM .
Category:
Viscum Ketones, Aldehydes, Acids Plants Disease Research Fields Inflammation/Immunology Loranthaceae
Target:
Cat. No.: HY-U00005
CAS No.: 145600-69-7
Target:
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AD 0261 is a radical scavenger which displays strong inhibitory action on the generation of lipid peroxides and superoxide anions.
Cat. No.: HY-N11564
CAS No.: 97399-89-8
Target:
Cat. No.: HY-N18241
CAS No.: 74635-97-5
Target:
Cat. No.: HY-N8447
CAS No.: 1891097-17-8
Target:
Cat. No.: HY-176403
CAS No.: 3058943-53-3
Target:
Research Areas:
FPR1 antagonist 3 (compound 10) is a potent and selective FPR1 antagonist. FPR1 antagonist 3 inhibits superoxide anion generation and elastase release with IC50s of 0.33 and 0.84 μM, respectively .
Cat. No.: HY-116730
CAS No.: 886755-63-1
Target:
Research Areas:
CHS-111 is a benzyl indazole inhibitor of superoxide anion O 2- generation. CHS-111 inhibits the cell migration, and reduces the formyl-Met-Leu-Phe- but not phorbol ester-stimulated phospholipase D activity, with the IC50 of 3.9 μM .
Cat. No.: HY-156241
Category:
Target:
Cat. No.: HY-121586
CAS No.: 59040-30-1
Synonyms: Bay g 6575
Target:
Research Areas:
Nafazatrom (Bay g 6575) is an orally active cardioprotective agent that protects against ischemic damage. Nafazatrom dose-dependently inhibits neutrophil aggregation, superoxide anion generation, arachidonic acid metabolism, and to a lesser extent the release of β-glucosidase, platelet aggregation or arachidonic acid in vitro. Acid metabolism has no significant effect. In a dog ischemia-reperfusion model, Nafazatrom (10 mg/kg; po) reduced infarct size and the occurrence of arrhythmias and rescued ischemic myocardial function without affecting any hemodynamic changes. The basis of Nafazatrom's cardioprotection may be inhibition of neutrophil function and cellular infiltration in vitro .
Cat. No.: HY-N19660
CAS No.: 1642784-96-0
Target:
Cat. No.: HY-N17409
CAS No.: 1275622-19-9
Category:
Simple Phenylpropanols Phenylpropanoids Plants Compositae Guilandina minax (Hance) G. P. Lewis
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
