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topical application

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5 alpha Reductase (1) Adrenergic Receptor (1) Antibiotic (3) Apoptosis (1) Autophagy (1) Bacterial (4) Endogenous Metabolite (1) Fungal (6) Glucocorticoid Receptor (4) Influenza Virus (1) Mitophagy (1) Parasite (2) Phosphodiesterase (PDE) (1) Phospholipase (1) Smo (1) Thyroid Hormone Receptor (1) TRP Channel (1) β-catenin (1)
By Research Areas:	Cancer (6) Endocrinology (3) Infection (8) Inflammation/Immunology (12) Neurological Disease (2)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-U00128

PPA-904	Parasite	Infection Inflammation/Immunology
PPA-904 is a specific phenothiazine photosensitizer in photodynamic research (PDT) research, especially topical application for cutaneous leishmaniasis in vivo .

HY-118978

PF-00277343	Thyroid Hormone Receptor	Endocrinology
PF-00277343 is a selective and skin-penetrable THR-β (K_i: 0.51 nM for THR-β, 8.0 nM for THR-α) agonist. PF-00277343 is effective against androgenetic alopecia in animal models .

HY-U00058R

Diflucortolone valerate (Standard)	Fungal Bacterial	Infection Inflammation/Immunology
Diflucortolone valerate (Standard) is the analytical standard of Diflucortolone valerate. This product is intended for research and analytical applications. Diflucortolone valerate is a powerful corticosteroid used topically for the research of various skin diseases .

HY-B0877R

Halcinonide (Standard)	Smo	Others
Halcinonide (Standard) is the analytical standard of Halcinonide. This product is intended for research and analytical applications. Halcinonide (SQ-18566) is a high potency corticosteroid used topically in the treatment of certain skin conditions.

HY-14603R

Clioquinol (Standard) Iodochlorohydroxyquinoline (Standard)	Fungal Autophagy Mitophagy Antibiotic Parasite	Infection Cancer
Clioquinol (Standard) is the analytical standard of Clioquinol. This product is intended for research and analytical applications. Clioquinol (Iodochlorhydroxyquin) is a topical antifungal agent with anticancer activity. Clioquinol acts as an oral antimicrobial agent for the research of diarrhea and skin infections. Antibiotic .

HY-13693R

Mometasone furoate (Standard) Sch32088 (Standard)	Glucocorticoid Receptor	Inflammation/Immunology Endocrinology Cancer
Mometasone furoate (Standard) is the analytical standard of Mometasone furoate. This product is intended for research and analytical applications. Mometasone furoate (Sch32088) is a?glucocorticoid receptor?agonist with anti-inflammatory and anti-allergic activity. Mometasone furoate acts as a corticosteroid agent and used for topical applications in chronic skin eczema and airway inflammation management of asthma in vivo

HY-13693

Mometasone furoate 2 Publications Verification Sch32088	Glucocorticoid Receptor	Inflammation/Immunology Endocrinology Cancer
Mometasone furoate (Sch32088) is a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic activity. Mometasone furoate acts as a corticosteroid agent and used for topical applications in chronic skin eczema and airway inflammation management of asthma in vivo

HY-B0141AR

Alpha-Estradiol (Standard) Alfatradiol(Standard); Epiestradiol(Standard); Epiestrol (Standard)	5 alpha Reductase Endogenous Metabolite Bacterial	Inflammation/Immunology
Alpha-Estradiol (Standard) is the analytical standard of Alpha-Estradiol. This product is intended for research and analytical applications. Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia.

HY-17569R

Difluprednate (Standard)	Phospholipase	Inflammation/Immunology
Difluprednate (Standard) is the analytical standard of Difluprednate. This product is intended for research and analytical applications. Difluprednate is a topical corticosteroid, which is thought to act by the induction of phospholipase A2 inhibitory proteins (lipocortins). Difluprednate is used for the symptomatic treatment of inflammation and pain associated with ocular surgery.

HY-129060R

Flutrimazole (Standard)	Fungal	Infection
Flutrimazole (Standard) is the analytical standard of Flutrimazole. This product is intended for research and analytical applications. Flutrimazole is an imidazole antifungal with dual anti-inflammatory and antifungal activity. Flutrimazole shows scarce transdermal penetration. Flutrimazole has the advantageous in the research of topical fungal infections with an inflammatory component .

HY-B1051R

Flumethasone (Standard)	Fungal	Inflammation/Immunology
Flumethasone (Standard) is the analytical standard of Flumethasone. This product is intended for research and analytical applications. Flumethasone is a corticosteroid, a topical agent used in combination with Clioquinol for the study of otitis externa and otomycosis. When used in animal models, Flumethasone's anti-inflammatory activity is 420 times higher than that of Cortisone.

HY-N0808R

Camphor (Standard)	TRP Channel Influenza Virus	Infection Inflammation/Immunology Cancer
Camphor (Standard) is the analytical standard of Camphor. This product is intended for research and analytical applications. Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities . Camphor is a TRPV3 agonist .

HY-106789

Plaunotol CS-684	Bacterial	Infection Inflammation/Immunology Cancer
Plaunotol is an orally active acyclic diterpene alcohol. Plaunotol has antibacterial activity against Helicobacter pylori which causes peptic ulcer . Plaunotol inhibits tumor angiogenesis and cell proliferation. Plaunotol induces apoptosis by activation of caspase 8 and caspase 9 pathways. Plaunotol is a potential anticancer agent against colon cancer .

HY-14283R

Luliconazole (Standard)	Fungal Antibiotic	Infection
Luliconazole (Standard) is the analytical standard of Luliconazole. This product is intended for research and analytical applications. Luliconazole (NND 502) is a topical antifungal imidazole antibiotic with broad-spectrum and potent antifungal activity. Luliconazole can be used for the research of skin infection, including dermatophytosis, tinea corporis, tinea pedis et al .

HY-19518R

Latanoprostene bunod (Standard)	Others	Neurological Disease
Latanoprostene bunod (Standard) is the analytical standard of Latanoprostene bunod. This product is intended for research and analytical applications. Latanoprostene bunod (LBN), a nitric oxide (NO)-donating prostaglandin F2a analog, is a topical ophthalmic therapeutic for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension (OHT) .

HY-B1360R

Chlorquinaldol (Standard)	Antibiotic Bacterial Fungal β-catenin Apoptosis	Infection Cancer
Chlorquinaldol (Standard) is the analytical standard of Chlorquinaldol. This product is intended for research and analytical applications. Chlorquinaldol (Chloquinan) is an antibacterial agent with the potential use in topical skin conditions and vaginal infections. Chlorquinaldol is a β-catenin/TCF4 inhibitor, showing anti-proliferation, anti-migration, and apoptosis-inducing activity in cancer cells .

HY-12720AR

Apraclonidine hydrochloride (Standard)	Adrenergic Receptor	Neurological Disease
Apraclonidine (hydrochloride) (Standard) is the analytical standard of Apraclonidine (hydrochloride). This product is intended for research and analytical applications. Apraclonidine hydrochloride (ALO 2145), a selective α2 and weak α1 receptor agonist activity, effectively lowers intraocular pressure (IOP) in human eyes. Apraclonidine hydrochloride is a topical ophthalmic solution and has the ability to elevate the eye lid .

HY-109085R

Difamilast (Standard)	Phosphodiesterase (PDE)	Inflammation/Immunology
Difamilast (Standard) is the analytical standard of Difamilast. This product is intended for research and analytical applications. Difamilast (OPA-15406) is a topical, selective and nonsteroidal phosphodiesterase-4 (PDE4) inhibitor with particularly efficient inhibition of subtype B (IC₅₀=11.2 nM). Difamilast can be used for the research of mild to moderate atopic dermatitis (AD) .

HY-15234R

Fluticasone furoate (Standard)	Glucocorticoid Receptor	Inflammation/Immunology
Fluticasone furoate (Standard) is the analytical standard of Fluticasone furoate. This product is intended for research and analytical applications. Fluticasone furoate is a topical, intranasal, enhanced-affinity synthetic trifluorinated corticosteroid with a K_d of 0.3 nM. Fluticasone furoate has potent anti-inflamatory and anti-asthmatic activity, and low systemic exposure. Fluticasone furoate has the potential for allergic rhinitis treatment .

HY-B0727R

Betamethasone valerate (Standard) Betamethasone 17-valerate (Standard)	Glucocorticoid Receptor	Inflammation/Immunology
Betamethasone valerate (Standard) is the analytical standard of Betamethasone valerate. This product is intended for research and analytical applications. Betamethasone valerate (Betamethasone 17-valerate), the 17-valerate ester of Betamethasone, is a topical corticosteroid with anti-inflammatory activity. Betamethasone valerate is used in the treatment of recurrent aphthous stomatitis. Betamethasone valerate inhibits the binding of the radiolabeled glucocorticoid dexamethasone ( ³H dexamethasone) to human epidermis and mouse skin with IC₅₀s of 5 and 6 nM, respectively .

Alpha-Estradiol (Standard) Alfatradiol(Standard); Epiestradiol(Standard); Epiestrol (Standard)	Structural Classification Classification of Application Fields Anti-aging Source classification Disease markers Phenols Endocrine diseases Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	5 alpha Reductase Endogenous Metabolite Bacterial
Alpha-Estradiol (Standard) is the analytical standard of Alpha-Estradiol. This product is intended for research and analytical applications. Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia.

Camphor (Standard)	Structural Classification Other Monoterpenes Terpenoids Source classification Plants Lauraceae Cinnamomum camphora	TRP Channel Influenza Virus
Camphor (Standard) is the analytical standard of Camphor. This product is intended for research and analytical applications. Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities . Camphor is a TRPV3 agonist .

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topical application

Inhibitors & Agonists

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Natural
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