6 Results for "

viable yeasts

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "viable yeasts" in MCE Product Catalog:

Zymosan (ZM), 95%
Zymosan (ZM), 95%
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Cat. No.: HY-159069
CAS No.: 9010-72-4
Purity:  95.02%
Zymosan (ZM), 95% is a yeast cell wall-derived carbohydrate-rich preparation and immunomodulator. Zymosan (ZM), 95% binds to and activates TLR-2, TLR-4, and Dectin-1 receptor to trigger downstream signaling pathways. Zymosan (ZM), 95% upregulates TLR-2, TLR-4, and TNF-α mRNA expression, increases serum TNF-α levels, and stimulates splenocyte number and viability in mice. Zymosan (ZM), 95% attenuates melanoma growth progression, modulates macrophage marker gene expression, and mediates phagocytosis, ROS generation, and cytokine production. Zymosan (ZM), 95% reduces Connexin 43 protein and mRNA levels, inhibits gap junctional intercellular communication, and induces proinflammatory factor production in human corneal cells. Zymosan (ZM), 95% induces peritoneal inflammation in mice, functions as a drug carrier, and supports fibroblast cell attachment in hydrogel formulations. Zymosan (ZM), 95% can be used for the research of melanoma, tumors, fungal keratitis, ocular surface inflammatory disorders, and peritoneal inflammation .
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Flindersine
Flindersine
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Cat. No.: HY-W984782
CAS No.: 523-64-8
Category:  

Rutaceae Extract Alkaloids Quinoline Alkaloids Plants Haplophyllum tuberculatum (Forssk.) A.Juss.

Target:  

GLUT Bacterial Fungal AMPK PPAR Reactive Oxygen Species (ROS) Apoptosis SOD

Flindersine is an alkaloid with multiple activities including antibacterial, antifungal, antitumor, and antidiabetic properties. Flindersine increases the activity of antioxidant enzymes, restores the levels of renal biomarkers, and reduces blood glucose, blood lipid, and insulin levels in diabetic rats. Flindersine inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, drug-resistant bacteria, as well as dermatophytes, filamentous fungi, and yeasts. Flindersine reduces the viability of cancer cells and induces apoptosis. Flindersine can be used in research related to breast cancer, type 2 diabetes, bacterial infections, and fungal infections .
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3-Oxo-hop-22(29)-ene
3-Oxo-hop-22(29)-ene
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Cat. No.: HY-N10440
CAS No.: 25615-11-6
Category:  

Cnidoscolus spinosus Lundell Triterpenes Terpenoids Plants Euphorbiaceae Extract

Target:  

Glycosidase

3-Oxo-hop-22(29)-ene is a yeast α-glucosidase inhibitor. 3-Oxo-hop-22(29)-ene shows a moderate effect on the viability of T. cruzi and L. mexicana. 3-Oxo-hop-22(29)-ene shows marginal activity of anti-inflammatory .
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D0870
D0870
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Cat. No.: HY-105206A
CAS No.: 149715-95-7
Synonyms: ZD0870
Target:  

Fungal

Research Areas:  

Infection

D0870 (ZD0870) is an antifungal agent that inhibits C. neoformans, vaginal candidiasis and viable yeasts .
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Omoconazole
Omoconazole
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Cat. No.: HY-164381
CAS No.: 74512-12-2
Target:  

Fungal

Research Areas:  

Infection

Omoconazole is an imidazole-derived azole antifungal agent. Omoconazole exhibits broad-spectrum in vitro activity against dermatophytes, yeasts, and dimorphic fungi, exerting fungistatic effects at low concentrations and fungicidal effects at high concentrations. Omoconazole accumulates in the skin, binds to keratin, and is slowly transferred from the stratum corneum to the viable epidermis. Omoconazole inhibits the growth of dermatophytes, impairs daughter cell separation in Candida albicans, induces cell wall thickening, disrupts intracellular cytoplasmic organelles, and leads to cell death. Omoconazole is used in studies related to dermatophytosis and superficial fungal infections .
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Chalcomoracin
Chalcomoracin
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Cat. No.: HY-N20674
CAS No.: 76472-89-4
Category:  

Moraceae Extract Morus alba L. Phenols Polyphenols Plants

Target:  

ERK JNK p38 MAPK PERK mTOR Akt MDM-2/p53 PINK1/Parkin Apoptosis Reactive Oxygen Species (ROS) Paraptosis Mitophagy Autophagy Bacterial Glycosidase

Chalcomoracin is an orally active anticancer agent. Chalcomoracin exhibits anticancer, antibacterial, and α-glucosidase inhibitory activities, with an IC50 of 14.23 µM against yeast α-glucosidase and an IC50 of 5.5 μM against FabI of Staphylococcus aureus. Chalcomoracin reduces the phosphorylation levels of ERK, JNK, and P38; enhances the phosphorylation level of ERK1/2; regulates the MAPK, mTOR, AKT, and p53 signaling pathways; upregulates the expression of Chop, Bip, PINK1, GRP78, and GADD153; and downregulates the expression of Alix. Chalcomoracin induces apoptosis (apoptosis), endoplasmic reticulum stress (endoplasmic reticulum stress), paraptosis (paraptosis), ROS production, mitophagy (mitophagy), and autophagy (autophagy); it inhibits cancer cell viability, colony-forming ability, migration, invasion, proliferation, tumorigenesis, fatty acid synthesis, S. aureus growth, vitreous-stimulated retinal cell activity, and cell cycle progression at the G0/G1 phase. Chalcomoracin can be used in research related to hepatocellular carcinoma, non-small cell lung cancer, triple-negative breast cancer, prostate cancer, proliferative vitreoretinopathy, pancreatic cancer, diabetes, and bacterial infections .
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