Dihydroxyacetone phosphate
Dihydroxyacetone phosphate (DHPA), a derivative of Dihydroxyacetone (DHA), is an important intermediate that participates in key pathways including glycolysis, lipid biosynthesis, and the plant Calvin cycle. Dihydroxyacetone phosphate can be used as a substrate and metabolic marker in biochemical research.
It is advisable to consider the salt form (Dihydroxyacetone phosphate hemimagnesium hydrate) that retains the same biological activity.
For research use only. We do not sell to patients.
- CAS No.: 57-04-5
- Formula: C3H7O6P
- Molecular Weight:170.06
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Description
IC50 & Target
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Human Endogenous Metabolite |
In Vitro
Dihydroxyacetone phosphate can be used in fructose metabolism, triose and glycation research[1].
Dihydroxyacetone phosphate has potential glycating effects to form advanced glycation end products (AGEs)[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 57-04-5
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Appearance Oil
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Molecular Weight 170.06
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Formula C3H7O6P
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Color Colorless to light yellow
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SMILES
O=C(COP(O)(O)=O)CO
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Synonyms
DHAP
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
H2O : ≥ 100 mg/mL (588.03 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Shimakawa G, et al. The Calvin cycle inevitably produces sugar-derived reactive carbonyl methylglyoxal during photosynthesis: a potential cause of plant diabetes. Plant Cell Physiol. 2014 Feb;55(2):333-40. [Content Brief]
[3]. Ahmad S, et al. Inhibitory effect of metformin and pyridoxamine in the formation of early, intermediate and advanced glycation end-products. PLoS One. 2013 Sep 4;8(9):e72128. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.8803 mL | 29.4014 mL | 58.8028 mL | 147.0069 mL |
| 5 mM | 1.1761 mL | 5.8803 mL | 11.7606 mL | 29.4014 mL | |
| 10 mM | 0.5880 mL | 2.9401 mL | 5.8803 mL | 14.7007 mL | |
| 15 mM | 0.3920 mL | 1.9601 mL | 3.9202 mL | 9.8005 mL | |
| 20 mM | 0.2940 mL | 1.4701 mL | 2.9401 mL | 7.3503 mL | |
| 25 mM | 0.2352 mL | 1.1761 mL | 2.3521 mL | 5.8803 mL | |
| 30 mM | 0.1960 mL | 0.9800 mL | 1.9601 mL | 4.9002 mL | |
| 40 mM | 0.1470 mL | 0.7350 mL | 1.4701 mL | 3.6752 mL | |
| 50 mM | 0.1176 mL | 0.5880 mL | 1.1761 mL | 2.9401 mL | |
| 60 mM | 0.0980 mL | 0.4900 mL | 0.9800 mL | 2.4501 mL | |
| 80 mM | 0.0735 mL | 0.3675 mL | 0.7350 mL | 1.8376 mL | |
| 100 mM | 0.0588 mL | 0.2940 mL | 0.5880 mL | 1.4701 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Dihydroxyacetone phosphate Related Classifications
HY-113131 Related Classifications
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