HS024 TFA
Based on 1 publication(s) in Google Scholar
HS024 is a selective MC4 receptor antagonist, with Kis of 0.29, 3.29, 5.45, 18.6 nM for MC4, MC5, MC3, and MC1, respectively. HS024 increase food intake.
For research use only. We do not sell to patients.
- Purity: 99.80%
- Formula: C58H79N19O10S2·xC2HF3O2
- Molecular Weight:1266.50 (free base)
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) HS024 TFA
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Biological Activity
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MC4R |
Chemical Information
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Appearance Solid
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Molecular Weight 1266.50 (free base)
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Formula C58H79N19O10S2·xC2HF3O2
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Color White to off-white
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Sequence
Ac-Cys-{Nle}-Arg-His-{D-2Nal}-Arg-Trp-Gly-Cys-NH2 (Disulfide bridge:Cys1-Cys9)
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Sequence Shortening
Ac-C-{Nle}-RH-{D-2Nal}-RWGC-NH2 (Disulfide bridge:Cys1-Cys9)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Neuroinflammation
A microglial LCN2-MC4R signaling axis drives silica-induced neuronal damage via C1q release. [Abstract]2026 Jan 23;23(1):70. PMID: 41578331
Solvent & Solubility
DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 50 mg/mL (Need ultrasonic)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)