KOdiA-PC
Based on 1 Customer Validation
Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species that are cytotoxic and proatherogenic. Many of these species were recently isolated and purified from oxLDL and identified as phosphatidylcholine species containing fragmented oxidized short-chain fatty acid residues at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine or KOdiA-PC is one of the most potent CD36 ligands of the oxLDL species. KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle and may be one of the more important structural determinants of oxLDL.
For research use only. We do not sell to patients.
- Purity : 95.45%
- CAS No.: 439904-33-3
- Formula: C32H58NO11P
- Molecular Weight:663.78
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Storage:
Solution, -20°C, 2 years
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
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Help & FAQs
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HY-134154
PAz-PC -
HY-130576
POVPCOxidized Phospholipid -
HY-141617
1-Palmitoyl-2-hydroxy-sn-glycero-3-PEOccurring Lysophospholipid -
HY-113369
Cholesteryl arachidonateEndogenous Metabolite -
HY-130502
5β,6β-EpoxycholestanolOxysterol -
HY-W583868
1-Palmitoyl-2-oleoyl-sn-glycero-3-PEPhospholipid -
HY-N8376
FustinAβ Inhibitor -
HY-125554
KDdiA-PCCD36 Ligand -
HY-126354
Palmitoyldocosahexaenoyl phosphatidylcholineEndogenous Metabolite -
HY-120991
1-Palmitoyl-2-linoleoyl-sn-glycero-3-PELipid -
HY-131389
Cholesteryl heptadecanoateCholesteryl Ester Internal Standard -
HY-130675AS
15(S)-HEPE-d5Stable Isotope
Biological Activity
Description
Chemical Information
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CAS No. 439904-33-3
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Appearance Liquid
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Molecular Weight 663.78
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Formula C32H58NO11P
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Color Colorless to light yellow
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SMILES
CCCCCCCCCCCCCCCC(OC[C@@H](OC(CCCC(/C=C/C(O)=O)=O)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Protocols
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Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Purity & Documentation
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Data Sheet (241 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KOdiA-PC Related Classifications
HY-126726 Related Classifications
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