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Cat. No.: HY-P10374

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Pep42

Pep42, a cyclic peptide ligand of GPR78, internalizes selectively into highly metastatic human melanoma cells through a receptor-mediated process.

For research use only. We do not sell to patients.

CAS No.: 900518-62-9
Formula: C₅₈H₉₄N₁₆O₁₆S₂
Molecular Weight:1335.59

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Pep42 Chemical Structure

CAS No.: 900518-62-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Pep42, a cyclic peptide ligand of GPR78, internalizes selectively into highly metastatic human melanoma cells through a receptor-mediated process^[1].

In Vitro

Pep42 represents a promising carrier to target the ER and deliver therapeutic agent organelle specific into cancer cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 900518-62-9
Molecular Weight 1335.59
Formula C₅₈H₉₄N₁₆O₁₆S₂
Sequence

Cys-Thr-Val-Ala-Leu-Pro-Gly-Gly-Tyr-Val-Arg-Val-Cys (disulfide:Cys1-Cys13)
Sequence Shortening

CTVALPGGYVRVC (disulfide:Cys1-Cys13)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Youngsoo Kim, et al. Targeting heat shock proteins on cancer cells: selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand. Biochemistry. 2006 Aug 8;45(31):9434-44. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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