SHP2-IN-14
SHP2-IN-14 (compound 27) is an orally active and potent SHP2 allosteric inhibitor (IC50=7 nM) with anti-tumor activity. SHP2-IN-14 inhibits tumor progression in NCI-H358 tumor bearing mice, exhibits good pharmacokinetic characteristics and safty.
For research use only. We do not sell to patients.
- CAS No.: 2673400-91-2
- Formula: C22H20Cl2N8O
- Molecular Weight:483.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2673400-91-2
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Molecular Weight 483.35
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Formula C22H20Cl2N8O
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SMILES
O=C(C1=C2C(C3=C(Cl)C(Cl)=NC=C3)=NNC2=NC(N4CCC(C5=CC=CC=C5)(N)CC4)=N1)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)