SILA-123

SILA-123 is a FLT3 inhibitor (FLT3-WT: IC50=2.1 nM; FLT3-ITD: IC50=1.0 nM). SILA-123 inhibits FLT3 phosphorylation and downstream signaling pathways, leading to apoptosis by arresting cell cycle progression at the G0/G1 phase. SILA-123 can be used in the study of acute myeloid leukemia.

For research use only. We do not sell to patients.

  • CAS No.: 2911585-37-8
  • Formula: C24H25N5O2
  • Molecular Weight:415.49
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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