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Referencia número: HY-187959

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SLC6A19-IN-6

SLC6A19-IN-6 is a B0AT1 (SLC6A19) inhibitor. SLC6A19-IN-6 inhibits sodium-dependent neutral amino acid transport. SLC6A19-IN-6 can be used for research on non-alcoholic steatohepatitis.

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No. CAS: 851269-95-9
Fòrmula: C₁₃H₁₈ClNO₂
Peso molecular:255.74

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

SLC6A19-IN-6 Chemical Structure

No. CAS: 851269-95-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

SLC6A19-IN-6 is a B0AT1 (SLC6A19) inhibitor. SLC6A19-IN-6 inhibits sodium-dependent neutral amino acid transport. SLC6A19-IN-6 can be used for research on non-alcoholic steatohepatitis^[1].

In Vitro

SLC6A19-IN-6 (Compound E4) (10 mM; 30 min) inhibits human B⁰AT1 in CHO-BC cells with an IC₅₀ of 13.7 µM in the FLIPR membrane potential assay, and acts primarily in a competitive manner^[1].
SLC6A19-IN-6 (6 min) inhibits human B⁰AT1 in CHO-BC cells with an IC₅₀ of 7.7 µM in a radioactive leucine/isoleucine flux assay^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 851269-95-9
Peso molecular 255.74
Fòrmula C₁₃H₁₈ClNO₂
SMILES

O=C(COC1=C(C)C=C(Cl)C=C1C)NC(C)C
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Yadav A, et al. Novel Chemical Scaffolds to Inhibit the Neutral Amino Acid Transporter BAT1 (SLC6A19), a Potential Target to Treat Metabolic Diseases. Frontiers in pharmacology. 2020;11:140. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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