1. PROTAC
  2. PROTAC Linker
  3. SMPH Crosslinker

SMPH Crosslinker 

Cat. No.: HY-124318
Handling Instructions

SMPH Crosslinker is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

SMPH Crosslinker Chemical Structure

SMPH Crosslinker Chemical Structure

CAS No. : 367927-39-7

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Description

SMPH Crosslinker is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl/ether

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Molecular Weight

379.36

Formula

C₁₇H₂₁N₃O₇

CAS No.

367927-39-7

SMILES

O=C(CCCCCNC(CCN1C(C=CC1=O)=O)=O)ON2C(CCC2=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

SMPH CrosslinkerPROTAC LinkerInhibitorinhibitorinhibit

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SMPH Crosslinker
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