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Art. -Nr.: HY-126373S

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SN-38 glucuronide-d₅

(Synonyms: SN-38G-d₅)

SN-38 glucuronide-d₅ (SN-38G-d₅) is the deuterium labeled SN-38 glucuronide (HY-126373). SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan (HY-16562) and has toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₂₈H₂₃D₅N₂O₁₁
Molecular Weight:573.56

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

SN-38 glucuronide-d₅ Chemical Structure

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Biologische Aktivität
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Bioz

Biologische Aktivität

Beschreibung

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anwendung

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 121080-63-5
Molecular Weight 573.56
Formel C₂₈H₂₃D₅N₂O₁₁
SMILES

O=C1OCC2=C([C@]1(CC)O)C=C3C4=NC5=CC=C(C=C5C(C([2H])([2H])C([2H])([2H])[2H])=C4CN3C2=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(O)=O)O)O)O
Synonyms

SN-38G-d₅
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.