Sootepin D
Sootepin D (compound 6), a triterpene from the apical bud of Gardenia sootepensis, inhibits TNF-α-induced NF-κB activity with an IC50 of 8.3μM. Sootepin D has anti-inflammatory activity.
For research use only. We do not sell to patients.
- CAS No.: 1154518-97-4
- Formula: C31H48O4
- Molecular Weight:484.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
NF-κB |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BT-474 | IC50 |
>10 μg/mL
Compound: 4
|
Cytotoxicity against human BT474 cells after 3 days by MTT assay
Cytotoxicity against human BT474 cells after 3 days by MTT assay
|
[PMID: 19456120] |
| HepG2 | IC50 |
>10 μg/mL
Compound: 4
|
Cytotoxicity against human HepG2 cells after 3 days by MTT assay
Cytotoxicity against human HepG2 cells after 3 days by MTT assay
|
[PMID: 19456120] |
| SW-620 | IC50 |
>10 μg/mL
Compound: 4
|
Cytotoxicity against human SW620 cells after 3 days by MTT assay
Cytotoxicity against human SW620 cells after 3 days by MTT assay
|
[PMID: 19456120] |
Chemical Information
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CAS No. 1154518-97-4
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Molecular Weight 484.71
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Formula C31H48O4
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SMILES
COC(CC[C@@]12[C@]3([C@](CC[C@H]2C(CO)=C)([H])[C@]4([C@@](C)([C@]([C@H](C)CC/C=C(C)/C=O)([H])CC4)CC3)C)C1)=O
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)