1. PROTAC
  2. PROTAC Linker
  3. SPDP-PEG24-acid

SPDP-PEG24-acid 

Cat. No.: HY-141354
Handling Instructions

SPDP-PEG24-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

SPDP-PEG24-acid Chemical Structure

SPDP-PEG24-acid Chemical Structure

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Description

SPDP-PEG24-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Molecular Weight

1343.63

Formula

C₅₉H₁₁₀N₂O₂₇S₂

SMILES

O=C(CCSSC1=NC=CC=C1)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

SPDP-PEG24-acidPROTAC LinkerInhibitorinhibitorinhibit

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SPDP-PEG24-acid
Cat. No.:
HY-141354
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