Alkaloids

Imidazole-5-propionic acid is a histidine metabolite.

3-Methylcarbazole (NSC 10154) Standard is the analytical standard of 3-Methylcarbazole (HY-W047478). This product is intended for research and analytical applications. 3-Methylcarbazole (NSC 10154) is a carbazole alkaloid with an IC₅₀ of 25 μg/mL against human fibrosarcoma cells. 3-Methylcarbazole inhibits mycelial growth and conidial germination of a variety of phytopathogenic fungi. 3-Methylcarbazole exhibits anti-inflammatory and antitumor activities. 3-Methylcarbazole can be used in studies related to fibrosarcoma, phytopathogenic fungal infections and inflammatory diseases.

4-Methyl-5,6,7,8-tetrahydroquinoline, a tetrahydroquinoline alkaloid, is isolated from the roots of Glycyrrhiza uralensis Fisch.

(±) Anabasine (Standard) is the analytical standard of (±) Anabasine (HY-W052144). This product is intended for research and analytical applications. (±) Anabasine is the racemic form of Anabasine (HY-B1532). (±) Anabasine stimulates the release of [³H]-Dopamine from mouse striatal synaptosomes. (±) Anabasine inhibits the high-affinity binding of [³H]-S-(-)-Nicotine to the striatal membrane. Anabasine is an agonist of α7nAChR and possesses anti-inflammatory and insecticidal activities.

Methyl 6-bromo-1H-indole-3-carboxylate (Standard) is the analytical standard of Methyl 6-bromo-1H-indole-3-carboxylate (HY-W052289). This product is intended for research and analytical applications. Methyl 6-bromo-1H-indole-3-carboxylate is a marine-derived natural product with antitumor activity. Methyl 6-bromo-1H-indole-3-carboxylate showed growth inhibition against Staphylococcus epidermidis, exhibiting weak or moderate minimum inhibitory concentrations (MICs).

4-Hydroxy-1H-indole-3-carbaldehyde (Standard) (4-Hydroxyindole-3-carboxaldehyde (Standard)) is the analytical standard of 4-Hydroxy-1H-indole-3-carbaldehyde (HY-W091541). This product is intended for research and analytical applications. 4-Hydroxy-1H-indole-3-carbaldehyde is an indole alkaloid and a plant metabolite. 4-Hydroxy-1H-indole-3-carbaldehyde can serve as an intermediate for research related to organic synthesis.

Murrayafoline A (Standard) is the analytical standard of Murrayafoline A (HY-W100287). This product is intended for research and analytical applications. Murrayafoline A is a carbazole alkaloid that can be extracted from Murraya tetramera. Murrayafoline A directly targets Specificity protein 1 (Sp1), thereby inhibiting NF-κB and MAPK signaling pathways. Murrayafoline a induces a G0/G1-phase arrest in platelet-derived growth factor (PDGF)-stimulated vascular smooth muscle cells. Murrayafoline A attenuates the Wnt/β-catenin pathway by promoting the degradation of intracellular β-catenin proteins. Murrayafoline A enhances the contraction of rat ventricular myocytes and L-type calcium current by activating protein kinase C. Murrayafoline A inhibits LPS (HY-D1056)-induced neuroinflammation in vivo. Murrayafoline A can be used for the study of inflammation, vascular complications and colon cancer.

Nicotinic acid riboside (Standard) is the analytical standard of Nicotinic acid riboside (HY-W104368). This product is intended for research and analytical applications. Nicotinic acid riboside is a NAD+ precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD+ metabolism.

N-Methyltyramine (hydrochloride) (Standard) is the analytical standard of N-Methyltyramine (hydrochloride) (HY-W153159). This product is intended for research and analytical applications. N-Methyltyramine hydrochloride is an orally active α2-adrenoreceptor antagonist with an IC₅₀ value of 5.53 μM against rat targets. N-Methyltyramine hydrochloride blocks α2-adrenoreceptors, while inhibiting lipolysis, hyperactivity responses and small intestinal peristalsis in mice. N-Methyltyramine hydrochloride promotes gastrin release and pancreatic juice secretion, upregulates appetite, blood pressure, myocardial contraction frequency and contraction intensity, and increases renal blood flow, renal vascular resistance and mean peripheral arterial resistance. N-Methyltyramine hydrochloride relaxes mouse small intestinal smooth muscle and undergoes biotransformation in vivo to produce adrenaline. N-Methyltyramine hydrochloride can be used in studies related to gastrointestinal diseases.

Perlolyrin (Standard) (Tribulusterine (Standard)) is the analytical standard of Perlolyrin (HY-W783671). This product is intended for research and analytical applications. Perlolyrin (Tribulusterine) is an alkaloid that can be found in Tribulus terrestris. Perlolyrin is toxic.

2-(Methylamino)ethanol (Standard) is the analytical standard of 2-(Methylamino)ethanol (HY-Y1783). This product is intended for research and analytical applications. 2-(Methylamino)ethanol (N-Methylethanolamine) is an alkaloid that can be isolated from lentil seeds. 2-(Methylamino)ethanol is used as an organic building block in chemical synthesis and as a solvent for removing carbon dioxide from gas streams.

Benzamide (Standard) is the analytical standard of Benzamide. This product is intended for research and analytical applications. Benzamide (Benzenecarboxamide) is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH)-induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature.