2. Immunology/Inflammation
  3. STING
  4. STING agonist-7

STING agonist-7 is a non-nucleotide STING agonist. STING agonist-7 binds selectively to mouse STING but not human STING. STING agonist-7 penetrates cell membrane poorly.

For research use only. We do not sell to patients.

STING agonist-7 Chemical Structure

STING agonist-7 Chemical Structure

CAS No. : 2767442-46-4

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10 mg USD 480 In-stock
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Based on 1 publication(s) in Google Scholar

STING agonist-7 Related Antibodies

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Description

STING agonist-7 is a non-nucleotide STING agonist. STING agonist-7 binds selectively to mouse STING but not human STING. STING agonist-7 penetrates cell membrane poorly[1].

In Vitro

STING agonist-7 (compound 11) is active in biochemical assays but inactive in cellular reporter assays[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

STING agonist-7 Related Antibodies
Molecular Weight

336.30

Formula

C17H12N4O4
CAS No.
Appearance

Solid

Color

Light brown to brown

SMILES

O=C(C1=CC=CC2=C1OC(CNC(C3=C4N=CC=CN4N=C3)=O)=C2)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (185.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9735 mL 14.8677 mL 29.7354 mL
5 mM 0.5947 mL 2.9735 mL 5.9471 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9735 mL 14.8677 mL 29.7354 mL 74.3384 mL
5 mM 0.5947 mL 2.9735 mL 5.9471 mL 14.8677 mL
10 mM 0.2974 mL 1.4868 mL 2.9735 mL 7.4338 mL
15 mM 0.1982 mL 0.9912 mL 1.9824 mL 4.9559 mL
20 mM 0.1487 mL 0.7434 mL 1.4868 mL 3.7169 mL
25 mM 0.1189 mL 0.5947 mL 1.1894 mL 2.9735 mL
30 mM 0.0991 mL 0.4956 mL 0.9912 mL 2.4779 mL
40 mM 0.0743 mL 0.3717 mL 0.7434 mL 1.8585 mL
50 mM 0.0595 mL 0.2974 mL 0.5947 mL 1.4868 mL
60 mM 0.0496 mL 0.2478 mL 0.4956 mL 1.2390 mL
80 mM 0.0372 mL 0.1858 mL 0.3717 mL 0.9292 mL
100 mM 0.0297 mL 0.1487 mL 0.2974 mL 0.7434 mL
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STING agonist-7 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

STING agonist-72767442-46-4STING agonist7STING agonist 7STINGStimulator of Interferon GenesTMEM173MITAERISMPYSSTING agonistpenetrates cell membrane poorlyInhibitorinhibitorinhibit

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STING agonist-7
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HY-143896
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