Sulfo-NHS-Acetate
Based on 1 Customer Validation
Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 152305-87-8
- Formula: C6H7NO7S
- Molecular Weight:237.19
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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Alkyl-Chain |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 152305-87-8
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Appearance Solid
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Molecular Weight 237.19
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Formula C6H7NO7S
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Color White to off-white
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SMILES
O=S(C(C1)C(N(OC(C)=O)C1=O)=O)(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 125 mg/mL (527.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2160 mL | 21.0801 mL | 42.1603 mL | 105.4007 mL |
| 5 mM | 0.8432 mL | 4.2160 mL | 8.4321 mL | 21.0801 mL | |
| 10 mM | 0.4216 mL | 2.1080 mL | 4.2160 mL | 10.5401 mL | |
| 15 mM | 0.2811 mL | 1.4053 mL | 2.8107 mL | 7.0267 mL | |
| 20 mM | 0.2108 mL | 1.0540 mL | 2.1080 mL | 5.2700 mL | |
| 25 mM | 0.1686 mL | 0.8432 mL | 1.6864 mL | 4.2160 mL | |
| 30 mM | 0.1405 mL | 0.7027 mL | 1.4053 mL | 3.5134 mL | |
| 40 mM | 0.1054 mL | 0.5270 mL | 1.0540 mL | 2.6350 mL | |
| 50 mM | 0.0843 mL | 0.4216 mL | 0.8432 mL | 2.1080 mL | |
| 60 mM | 0.0703 mL | 0.3513 mL | 0.7027 mL | 1.7567 mL | |
| 80 mM | 0.0527 mL | 0.2635 mL | 0.5270 mL | 1.3175 mL | |
| 100 mM | 0.0422 mL | 0.2108 mL | 0.4216 mL | 1.0540 mL |
Sulfo-NHS-Acetate Related Classifications
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