1. NF-κB
  2. Keap1-Nrf2
  3. TAT-14

TAT-14 

Cat. No.: HY-P1328
Handling Instructions

TAT-14 is a 14-mer peptide that acts as Nrf2 activator with an anti-inflammatory effect. TAT-14 has no effect on Nrf2 mRNA expression, but increases Nrf2 protein level due to targeting the Nrf2 binding site on Keap1.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

TAT-14 Chemical Structure

TAT-14 Chemical Structure

CAS No. : 1362661-34-4

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Description

TAT-14 is a 14-mer peptide that acts as Nrf2 activator with an anti-inflammatory effect. TAT-14 has no effect on Nrf2 mRNA expression, but increases Nrf2 protein level due to targeting the Nrf2 binding site on Keap1[1].

IC50 & Target

IC50: Nrf2[1]

Molecular Weight

3173.59

Formula

C₁₃₇H₂₃₀N₄₈O₃₉

CAS No.

1362661-34-4

Sequence

Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Leu-Gln-Leu-Asp-Glu-Glu-Thr-Gly-Glu-Phe-Leu-Pro-Ile-Gln

Sequence Shortening

YGRKKRRQRRRLQLDEETGEFLPIQ

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

TAT-14TAT14TAT 14Keap1-Nrf2Nrf2ActivatorInhibitorinhibitorinhibit

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