Temuterkib (Standard) (Synonyms: LY3214996 (Standard))

Cat. No.: HY-101494R Purity: 98%: Handling Instructions
FAQs
Technical Support

Temuterkib (Standard) is the analytical standard of Temuterkib (HY-101494). This product is intended for research and analytical applications. Temuterkib (LY3214996) is a highly selective inhibitor of ERK1 and ERK2, with IC50 of 5 nM for both enzymes in biochemical assays. Temuterkib potently inhibits cellular p-RSK1 in BRAF and RAS mutant cancer cell lines. Temuterkib shows potent antitumor activities in cancer models with MAPK pathway alterations.

For research use only. We do not sell to patients.

Temuterkib (Standard) Chemical Structure

CAS No. : 1951483-29-6

Size	Stock	Quantity
1 mg	Get quote 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks	Estimated Time of Arrival: December 31
5 mg	Get quote 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks	Estimated Time of Arrival: December 31
10 mg	Get quote 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks	Estimated Time of Arrival: December 31
25 mg	Get quote 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks	Estimated Time of Arrival: December 31
50 mg	Get quote 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks	Estimated Time of Arrival: December 31
100 mg	Get quote 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

Synthetic products have potential research and development risk.

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Product Information
Purity & Documentation
Customer Review

Information	Temuterkib (Standard) is the analytical standard of Temuterkib (HY-101494). This product is intended for research and analytical applications. Temuterkib (LY3214996) is a highly selective inhibitor of ERK1 and ERK2, with IC50 of 5 nM for both enzymes in biochemical assays. Temuterkib potently inhibits cellular p-RSK1 in BRAF and RAS mutant cancer cell lines. Temuterkib shows potent antitumor activities in cancer models with MAPK pathway alterations.
Application	The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight	453.56
Formula	C₂₂H₂₇N₇O₂S
CAS No.	1951483-29-6
SMILES	O=C(C(C=C(C1=NC(NC2=CC=NN2C)=NC=C1)S3)=C3C4(C)C)N4CCN5CCOCC5
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Temuterkib (Standard) Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Temuterkib (Standard)1951483-29-6LY3214996 (Standard)Reference StandardsERKExtracellular signal regulated kinasesInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Requested Quantity *

Applicant Name *

Salutation

Email Address *

Phone Number *

Department

Organization Name *

City

State

Country or Region *

Remarks

Product Name

Lot #

Applicant Name *

Email Address *

Phone Number

Department *

Organization Name *

Country or Region *

Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

Temuterkib (Standard) (Synonyms: LY3214996 (Standard))

Product Information

Purity & Documentation

Customer Review

Temuterkib (Standard) Related Classifications

Molarity Calculator

Dilution Calculator