Temuterkib (Standard)

(Synonyms: LY3214996 (Standard))

Temuterkib (Standard) is the analytical standard of Temuterkib (HY-101494). This product is intended for research and analytical applications. Temuterkib (LY3214996) is a highly selective inhibitor of ERK1 and ERK2, with IC50 of 5 nM for both enzymes in biochemical assays. Temuterkib potently inhibits cellular p-RSK1 in BRAF and RAS mutant cancer cell lines. Temuterkib shows potent antitumor activities in cancer models with MAPK pathway alterations.

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  • CAS No.: 1951483-29-6
  • Formule: C22H27N7O2S
  • Masse moléculaire:453.56
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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