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Tetraasterane is a hydrophobic tag that promotes the degradation of ALK protein. Tetraasterane can be used for synthesis of ALK degrader 3 (HY-182087).

For research use only. We do not sell to patients.

Tetraasterane

Tetraasterane Chemical Structure

CAS No. : 259-77-8

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Tetraasterane Related Antibodies

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Description

Tetraasterane is a hydrophobic tag that promotes the degradation of ALK protein. Tetraasterane can be used for synthesis of ALK degrader 3 (HY-182087)[1].

In Vitro

Tetraasterane (7 days) conjugated with ALK degrader 3 potently inhibits the proliferation of H3122 cells, with an IC50 of 97.77 nM[1].
Tetraasterane (0.05-2 μM; 24 h) conjugated with ALK degrader 3 induces concentration-dependent degradation of ALK protein in H3122 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tetraasterane Related Antibodies
Molecular Weight

160.26

Formula

C12H16
CAS No.
SMILES

C12C(CC3C4C2)C5C1CC4C3C5
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Tetraasterane Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tetraasterane259-77-8HyTHydrophobie tagginghydrophobic tagALK proteinInhibitorinhibitorinhibit

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